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NCT03397706 2025-03-20

Dose Escalation & Expansion Study of Oral VRx-3996 & Valganciclovir in Subjects With EBV+ Lymphoid Malignancies

Phase 1/2 Completed

64 enrolled 31 charts

Lymphoid

Lymphoproliferative Disorders

NCT05578820 2024-07-01

Safety, Tolerability and Pharmacokinetics Investigation of Stimotimagene Copolymerplasmid

Phase 1 Completed

21 enrolled

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckSarcoma

Squamous Cell Carcinoma of Head and Neck, Anus Neoplasms, Breast Neoplasms, Uterine Cervical Neoplasms, Melanoma, Penile Neoplasms, Sarcoma, Vulvar Neoplasms

NCT00002824 2019-03-13

Gene Therapy in Treating Patients With Primary Brain Tumors

Phase 1 Completed

CNSSarcoma

Astrocytoma, Brain Neoplasms, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00530218 2017-12-02

Ganciclovir by Infusion and by Mouth in Treating Patients With Cytomegalovirus After Donor Bone Marrow Transplant

Phase 2 Completed

61 enrolled 6 charts

LymphoidMyeloidOther hematologic neoplasmPlasma cell

Leukemia, Lymphoma, Multiple Myeloma, Myeloproliferative Disorders, Myelodysplastic-Myeloproliferative Diseases

NCT00001328 2017-07-02

Gene Therapy for the Treatment of Brain Tumors

Phase 1 Completed

15 enrolled

CNS

Brain Neoplasms, Neoplasm Metastasis, Neoplasms, Multiple Acyl Coenzyme A Dehydrogenase Deficiency

NCT00006264 2016-02-03

Zidovudine Plus Interleukin-2 and Ganciclovir in Treating Patients With AIDS-Related Primary Central Nervous System Lymphoma

Phase 2 Completed

Lymphoid

Lymphoma

NCT00716911 2015-06-08

Measuring Changes in Blood in Patients at High Risk of Cytomegalovirus Infection After Undergoing Donor Bone Marrow Transplant or Peripheral Blood Stem Cell Transplant

Phase NA Completed

100 enrolled

DermatologicLymphoidMyeloidOther hematologic neoplasmPlasma cell

Pdgfra-Associated Chronic Eosinophilic Leukemia, Blast Crisis, Burkitt Lymphoma, Cytomegalovirus Infections, Hodgkin Disease, Leukemia, Leukemia, Hairy Cell, Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Multiple Myeloma, Mycosis Fungoides, Myelodysplastic Syndromes, Myeloproliferative Disorders, Sezary Syndrome, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myeloid, Accelerated Phase, Leukemia, Myeloid, Chronic-Phase, Leukemia, Neutrophilic, Chronic, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, T-Cell, Cutaneous, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Neoplasms, Plasma Cell, Myelodysplastic-Myeloproliferative Diseases, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative, Primary Myelofibrosis

NCT00005057 2015-04-29

Gene Therapy and Ganciclovir in Treating Patients With Stage IV Melanoma

Phase 1 Completed

Dermatologic

Melanoma

NCT02202564 2014-07-29

Preliminary Results for the Double-dose Adenovirus-mediated Adjuvant Therapy Improving Outcome of Liver Transplantation in Patients With Advanced Hepatocellular Carcinoma

Phase 2 Completed

81 enrolled

Gastrointestinal

Carcinoma, Hepatocellular, Liver Neoplasms

NCT00006340 2013-07-26

Ganciclovir Plus Arginine Butyrate in Treating Patients With Cancer or Lymphoproliferative Disorders Associated With the Epstein Barr Virus

Phase 1 Completed

DermatologicLymphoidOther hematologic neoplasmOther neoplasmSarcoma

Burkitt Lymphoma, Hodgkin Disease, Immunoblastic Lymphadenopathy, Leukemia, Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Mycosis Fungoides, Precancerous Conditions, Recurrence, Sezary Syndrome, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, T-Cell, Cutaneous, Lymphoma, Large-Cell, Anaplastic, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Leukemia, Large Granular Lymphocytic, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Dendritic Cell Sarcoma, Interdigitating

NCT00217503 2013-06-20