Clinical Trials

1,503 enrolled

Prostatic Neoplasms

NCT06065748 2026-06-04

A Study to Evaluate Efficacy and Safety of Giredestrant Compared With Fulvestrant (Plus a CDK4/6 Inhibitor), in Participants With ER-Positive, HER2-Negative Advanced Breast Cancer Resistant to Adjuvant Endocrine Therapy (pionERA Breast Cancer)

Phase 3 Recruiting

1,050 enrolled

Estrogen Receptor-Positive, HER2-Negative Advanced Breast Cancer

NCT04961996 2026-05-22

A Study Evaluating the Efficacy and Safety of Adjuvant Giredestrant Compared With Physician's Choice of Adjuvant Endocrine Monotherapy in Participants With Estrogen Receptor-Positive, HER2-Negative Early Breast Cancer (lidERA Breast Cancer)

4,170 enrolled

Breast Neoplasms

NCT04546009 2026-05-19

A Study Evaluating the Efficacy and Safety of Giredestrant Combined With Palbociclib Compared With Letrozole Combined With Palbociclib in Participants With Estrogen Receptor-Positive, HER2-Negative Locally Advanced or Metastatic Breast Cancer (persevERA Breast Cancer)

992 enrolled

Breast Neoplasms

NCT01368588 2026-05-08

Androgen-Deprivation Therapy and Radiation Therapy in Treating Patients With Prostate Cancer

2,590 enrolled 18 charts

Prostatic Neoplasms

NCT04136353 2026-05-06

DASL-HiCaP

1,100 enrolled

Prostatic Neoplasms

NCT05306340 2026-04-30

A Study Evaluating the Efficacy and Safety of Giredestrant Plus Everolimus Compared With the Physician's Choice of Endocrine Therapy Plus Everolimus in Participants With Estrogen Receptor-Positive, HER2-Negative, Locally Advanced or Metastatic Breast Cancer (evERA Breast Cancer)

373 enrolled

Breast Neoplasms

NCT04964934 2026-04-21

SERENA-6

315 enrolled

Breast Diseases, Breast Neoplasms, Neoplasm Metastasis, Neoplasms, Neoplasms by Site

NCT05296798 2026-04-16

A Study to Evaluate the Efficacy and Safety of Giredestrant in Combination With Phesgo (Pertuzumab, Trastuzumab, and Hyaluronidase-zzxf) Versus Phesgo in Participants With Locally Advanced or Metastatic Breast Cancer (heredERA Breast Cancer)

922 enrolled

Breast Neoplasms

NCT06382948 2026-04-03

ADELA

Phase 3 Recruiting

240 enrolled

Advanced Breast Cancer

NCT00936390 2026-03-06

Radiation Therapy With or Without Androgen-Deprivation Therapy in Treating Patients With Prostate Cancer

1,538 enrolled 37 charts

Prostatic Neoplasms

NCT01546987 2026-03-06

Hormone Therapy, Radiation Therapy, and Steroid 17alpha-monooxygenase TAK-700 in Treating Patients With High-Risk Prostate Cancer

239 enrolled 38 charts

Prostatic Neoplasms

NCT00066690 2026-02-06

SOFT

3,066 enrolled 15 charts

Breast Neoplasms

NCT00066703 2026-02-06

TEXT

2,672 enrolled 14 charts

Breast Neoplasms

NCT03009981 2025-12-18

A Study of Androgen Annihilation in High-Risk Biochemically Relapsed Prostate Cancer

504 enrolled

Prostatic Neoplasms

NCT04711252 2025-10-14

SERENA-4

1,370 enrolled

Breast Diseases, Breast Neoplasms, Neoplasm Metastasis, Neoplasms, Neoplasms by Site, Skin Diseases

NCT00567580 2025-05-09

Prostate Radiation Therapy or Short-Term Androgen Deprivation Therapy and Pelvic Lymph Node Radiation Therapy With or Without Prostate Radiation Therapy in Treating Patients With a Rising Prostate Specific Antigen (PSA) After Surgery for Prostate Cancer

1,792 enrolled 27 charts

Prostatic Neoplasms

NCT03777982 2024-09-19

Conventional Androgen Deprivation Therapy (ADT) With or Without Abiraterone Acetate + Prednisone and Apalutamide Following a Detectable PSA After Radiation and ADT

Phase 3 Terminated

12 enrolled 5 charts

Prostatic Neoplasms

NCT05891093 2024-02-08

Efficacy and Safety of Fluzoparib Combined With Adjuvant Endocrine Therapy for HR+/HER2- SNF3-subtype Early Breast Cancer (BCTOP-L-A01)

Phase 3 Recruiting

766 enrolled

Breast Neoplasms

NCT00430183 2023-02-09

Surgery With or Without Docetaxel and Leuprolide or Goserelin in Treating Patients With High-Risk Localized Prostate Cancer

788 enrolled 10 charts

Prostatic Neoplasms

NCT00288080 2022-06-21

Hormone Therapy and Radiation Therapy or Hormone Therapy and Radiation Therapy Followed by Docetaxel and Prednisone in Treating Patients With Localized Prostate Cancer

612 enrolled 11 charts

Prostatic Neoplasms

NCT00005044 2022-06-15

Hormone Therapy and Radiation Therapy in Treating Patients With Prostate Cancer

1,579 enrolled 13 charts

Prostatic Neoplasms

NCT00004054 2020-10-22

Hormone Therapy Plus Radiation Therapy With or Without Combination Chemotherapy in Treating Patients With Prostate Cancer

397 enrolled 11 charts

Prostatic Neoplasms

NCT00079001 2020-05-12

Zoledronate in Preventing Skeletal (Bone)-Related Events in Men Who Are Receiving Androgen Deprivation Therapy For Prostate Cancer and Bone Metastases

645 enrolled 13 charts

Neoplasm Metastasis, Prostatic Neoplasms

NCT01638247 2018-09-19

MALE

56 enrolled

Breast Neoplasms, Male

NCT00329797 2017-11-29

Zoledronate in Preventing Osteoporosis and Bone Fractures in Patients With Locally Advanced Nonmetastatic Prostate Cancer Undergoing Radiation Therapy and Hormone Therapy

109 enrolled 8 charts

Osteoporosis, Prostatic Neoplasms

NCT02483767 2017-10-17

POF

98 enrolled

Breast Neoplasms

NCT00066807 2016-10-28

PERCHE

Phase 3 Terminated

29 enrolled 6 charts

Breast Neoplasms

NCT00659373 2016-07-25

Co-SOFT

86 enrolled 4 charts

Breast Neoplasms, Fatigue, Sleep Wake Disorders

NCT00003290 2013-12-04

Radiation Therapy in Treating Patients With Prostate Cancer

800 enrolled

Prostatic Neoplasms

NCT00363285 2013-08-26

Cyproterone Acetate in Treating Patients With Newly Diagnosed Stage III or Stage IV Prostate Cancer

900 enrolled

Prostatic Neoplasms

NCT00175383 2013-04-11

Long Acting LHRH Versus Short Acting LHRH in the Treatment of Prostate Cancer

100 enrolled

Prostatic Neoplasms

NCT01581944 2012-04-20

Gonadotropin-releasing Hormone Agonist Prior to Myomectomy

68 enrolled

Hemorrhage, Leiomyoma

NCT00626431 2011-07-19

A Study of Leuprolide to Treat Prostate Cancer

310 enrolled 17 charts

Prostatic Neoplasms

NCT00764166 2008-10-01

RisingPSA