Clinical Trials Browser

Anemia, Blast Crisis, Breast Neoplasms, Hodgkin Disease, Lymphoma, Non-Hodgkin, Multiple Myeloma, Myelodysplastic Syndromes, Myeloproliferative Disorders, Neoplasm Metastasis, Pancreatic Neoplasms, Prostatic Neoplasms, Thrombocytosis, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Accelerated Phase, Leukemia, Myeloid, Chronic-Phase, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Hematologic Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Myelodysplastic-Myeloproliferative Diseases, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative, Primary Myelofibrosis

NCT04817956 2024-02-29

IMPRESS-N

Phase 2 Recruiting

3,000 enrolled

Tumor-Agnostic

Neoplasm Metastasis

NCT02925234 2024-01-24

DRUP

Phase 2 Recruiting

1,550 enrolled

Tumor-Agnostic

Neoplasms

NCT05238831 2024-01-23

SMMART Adaptive Clinical Treatment (ACT) Trial

Phase EARLY_PHASE1 Withdrawn

BreastGastrointestinalGenitourinaryGynecologicSarcoma

Breast Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Sarcoma

NCT02073838 2023-09-29

Ribavirin and Hedgehog Inhibitor With or Without Decitabine in AML

Phase 2 Completed

23 enrolled

Other hematologic neoplasm

Leukemia, Myeloid, Acute

NCT03158389 2023-09-28

N²M²

Phase 1/2 Completed

228 enrolled

CNS

Glioblastoma

NCT02667574 2022-10-17

VISMONEO

Phase 2 Completed

55 enrolled

Dermatologic

Carcinoma, Basal Cell

NCT03610022 2022-08-18

OPTIVISMO-1

Phase 4 Completed

27 enrolled

Dermatologic

Carcinoma, Basal Cell

NCT03035188 2022-02-11

NICCI

Phase 2 Completed

40 enrolled

Dermatologic

Carcinoma, Basal Cell

NCT02436408 2021-10-28

VISORB

Phase 4 Completed

35 enrolled 9 charts

Dermatologic

Carcinoma, Basal Cell

NCT03052478 2021-06-08

Study of Vismodegib in Advanced Gastric Adenocarcinoma Patients With SMO Overexpression

Phase 2 Completed

10 enrolled

Gastrointestinal

Stomach Neoplasms

NCT01835626 2021-05-03

Phase II Study of Radiation Therapy and Vismodegib for Advanced Head/Neck Basal Cell Carcinoma

Phase 2 Completed

24 enrolled 16 charts

DermatologicHead & Neck

Head and Neck Neoplasms, Skin Neoplasms

NCT02366312 2021-02-18

KCOT

Phase 2 Completed

2 enrolled 8 charts

Odontogenic Cysts

NCT00957229 2021-01-11

GDC-0449

Phase 2 Completed

41 enrolled 10 charts

Dermatologic

Basal Cell Nevus Syndrome

NCT01556009 2020-11-02

Vismodegib

Phase 2 Completed

24 enrolled

Dermatologic

Basal Cell Nevus Syndrome, Carcinoma, Basal Cell

NCT02956889 2020-01-29

virgilio

Phase 2 Terminated

14 enrolled

Dermatologic

Carcinoma, Basal Cell

NCT03767439 2019-12-18

Nivolumab With Vismodegib in Patients With Basal Cell Nevus Syndrome

Phase 2 Withdrawn

Dermatologic

Basal Cell Nevus Syndrome

NCT02067104 2019-08-14

Vismodegib in Basal Cell Carcinomas (BCC) Chemoprevention

Phase 2 Terminated

9 enrolled 4 charts

Dermatologic

Carcinoma, Basal Cell

NCT01700049 2019-05-23

Study Evaluating the Efficacy of Oral Vismodegib in Various Histologic Subtypes

Phase 2 Completed

28 enrolled 9 charts

Dermatologic

Carcinoma, Basal Cell

NCT01601184 2019-05-21

Study of Vismodegib in Combination With Temozolomide Versus Temozolomide Alone in Patients With Medulloblastomas With an Activation of the Sonic Hedgehog Pathway

Phase 1/2 Terminated

24 enrolled

CNS

Microphthalmia, Isolated, with Coloboma 5, Medulloblastoma

NCT01088815 2019-04-26

Hedgehog Inhibitors for Metastatic Adenocarcinoma of the Pancreas

Phase 2 Completed

98 enrolled 14 charts

Gastrointestinal

Adenocarcinoma, Carcinoma, Digestive System Diseases, Digestive System Neoplasms, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Pancreatic Diseases, Pancreatic Neoplasms

NCT01537107 2019-04-08