Clinical Trials Browser

NCT03598595 2026-05-14

Gemcitabine, Docetaxel, and Hydroxychloroquine in Treating Participants With Recurrent or Refractory Osteosarcoma

Phase 1/2 Active not recruiting

31 enrolled

Sarcoma

Osteosarcoma

NCT05036226 2026-05-13

COAST

Phase 1/2 Recruiting

76 enrolled

GenitourinaryOther solid neoplasm

Prostate Cancer Recurrent

NCT04464759 2026-05-11

LIMIT

Phase 1/2 Recruiting

94 enrolled

Dermatologic

Melanoma

NCT05842174 2026-04-16

TAQE

Phase 1/2 Recruiting

93 enrolled

Gastrointestinal

Carcinoma, Hepatocellular

NCT04201457 2026-02-03

A Trial of Dabrafenib, Trametinib and Hydroxychloroquine for Patients With Recurrent LGG or HGG With a BRAF Aberration

Phase 1/2 Active not recruiting

57 enrolled

CNS

Glioma

NCT01506973 2025-07-25

A Study of Hydroxychloroquine in Combination With Gemcitabine/Abraxane in Pancreatic Cancer

Phase 1/2 Completed

119 enrolled

Tumor-Agnostic

Adenocarcinoma

NCT06939582 2025-04-29

RIOM

Phase 1/2 Recruiting

158 enrolled

Other

Radiation-induced Oral Mucositis

NCT03774472 2025-02-17

Hydroxychloroquine, Palbociclib, and Letrozole Before Surgery in Treating Patients With Estrogen Receptor Positive, HER2 Negative Breast Cancer

Phase 1/2 Completed

15 enrolled 11 charts

Breast

Anatomic Stage I Breast Cancer AJCC v8

NCT04214418 2024-12-18

MEKiAUTO

Phase 1/2 Terminated

27 enrolled 12 charts

Gastrointestinal

Gastrointestinal Neoplasms

NCT06328387 2024-03-25

HCQ+ADC vs ADC in the Treatment of Advanced Breast Cancer

Phase 1/2 Unknown

120 enrolled

Breast

Breast Neoplasms

NCT03513211 2023-11-22

HITMAN-PC

Phase 1/2 Completed

12 enrolled

Genitourinary

Prostatic Neoplasms

NCT00765765 2023-08-09

Ixabepilone and Hydroxychloroquine in Treating Patients With Metastatic Breast Cancer

Phase 1/2 Terminated

6 enrolled 7 charts

Breast

Breast Neoplasms, Breast Neoplasms, Male

NCT04593758 2023-05-24

To Evaluate Maximally Tolerated Dose (MTD), Safety and Efficacy of CPI-613® (Devimistat) Plus Hydroxychloroquine in Patients With Relapsed or Refractory Clear Cell Sarcoma of Soft Tissue

Phase 1/2 Completed

16 enrolled

Sarcoma

Sarcoma, Clear Cell

NCT03754179 2021-04-28

COMBI-R2

Phase 1/2 Unknown

63 enrolled

Dermatologic

Melanoma

NCT03081702 2021-04-02

A Study of the Safety, Tolerability and Effectiveness of Hydroxychloroquine and Itraconazole in Platinum-resistant Epithelial Ovarian Cancer

Phase 1/2 Completed

13 enrolled

Gynecologic

Platinum-resistant Epithelial Ovarian Cancer

NCT03400254 2020-04-28

GLACIER

Phase 1/2 Withdrawn

Breast

Breast Neoplasms

NCT01550367 2020-01-02

Study of Hydroxychloroquine and Aldesleukin in Renal Cell Carcinoma Patients (RCC)

Phase 1/2 Completed

30 enrolled 20 charts

Genitourinary

Carcinoma, Renal Cell

NCT00486603 2019-07-10

Hydroxychloroquine, Radiation, and Temozolomide Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Phase 1/2 Completed

92 enrolled 18 charts

CNSSarcoma

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT01128296 2019-05-01

Study of Pre-surgery Gemcitabine + Hydroxychloroquine (GcHc) in Stage IIb or III Adenocarcinoma of the Pancreas

Phase 1/2 Completed

35 enrolled 14 charts

Gastrointestinal

Pancreatic Neoplasms

NCT01206530 2019-04-18

FOLFOX/Bevacizumab/Hydroxychloroquine (HCQ) in Colorectal Cancer

Phase 1/2 Completed

50 enrolled

Gastrointestinal

Adenocarcinoma, Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms

NCT00728845 2017-05-23

Hydroxychloroquine, Carboplatin, Paclitaxel, and Bevacizumab in Recurrent Advanced Non-Small Cell Lung Cancer

Phase 1/2 Terminated

8 enrolled 6 charts

Thoracic

Adenocarcinoma of Lung, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT00809237 2013-12-10

Hydroxychloroquine and Gefitinib to Treat Lung Cancer

Phase 1/2 Unknown

71 enrolled

Thoracic

Carcinoma, Non-Small-Cell Lung