Announcements Trials
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Phase

Phase 1/2 5Phase 1 5Phase 3 1

Status

Completed 3Withdrawn 2

Sponsor Class

INDUSTRY 3NIH 1NETWORK 1

Study Type

Interventional 5

Sponsor

Cancer Type

CNS 5Sarcoma 1

Conditions

Glioma 4Glioblastoma 3Astrocytoma 3Recurrence 2Central Nervous System Neoplasms 2Neoplasms 1Gliosarcoma 1Brain Neoplasms 1

Interventions

pembrolizumab 410Cyclophosphamide 394Carboplatin 306Gemcitabine 286Nivolumab 276Paclitaxel 274Cisplatin 252Radiotherapy 225Dexamethasone 210Bevacizumab 209fludarabine 192Docetaxel 187Rituximab 183Capecitabine 171Oxaliplatin 158Lenalidomide 157Fluorouracil 152Temozolomide 138Cytarabine 135Etoposide 128Irinotecan 124Cetuximab 123fludarabine phosphate 120Injections 118venetoclax 116Ipilimumab 115Doxorubicin 114Azacitidine 108130-nm albumin-bound paclitaxel 108Pemetrexed 107

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Phase 1/2 × Interventional × IL13-PE38 × Clear all
NCT00024570 2014-11-14

Interstitial Infusion of IL13-PE38QQR Cytotoxin in Recurrent Malignant Glioma

INSYS Therapeutics Inc

Phase 1/2 Completed
60 enrolled
CNS

Astrocytoma, Glioblastoma, Glioma, Recurrence

NCT00378235 2014-11-13

Phase I/II Trial of Intracerebral IL13-PE38QQR Infusions in Pediatric Patients With Recurrent Malignant Glioma

INSYS Therapeutics Inc

Phase 1/2 Withdrawn
CNS

Glioma, Recurrence

NCT00006268 2013-06-24

Immunotoxin Therapy in Treating Patients With Malignant Glioma

National Cancer Institute (NCI)

Phase 1/2 Completed
CNSSarcoma

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Central Nervous System Neoplasms, Gliosarcoma

NCT00041587 2011-06-06

Pre-operative IL13-PE38QQR in Patients With Recurrent or Progressive Malignant Glioma

INSYS Therapeutics Inc

Phase 1/2 Completed
80 enrolled
CNS

Astrocytoma, Glioblastoma, Glioma, Neoplasms

NCT00053040 2010-09-24

Immunotoxin Therapy in Treating Children With Recurrent Malignant Gliomas

Pediatric Brain Tumor Consortium

Phase 1/2 Withdrawn
CNS

Central Nervous System Neoplasms

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