Announcements Trials
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Phase

Phase 2 2Phase 1/2 2Phase 1 1

Status

Completed 7Terminated 5Withdrawn 1

Sponsor Class

OTHER 2INDUSTRY 2NIH 1

Study Type

Interventional 5

Sponsor

Cancer Type

Thoracic 1Other solid neoplasm 1Gynecologic 1Genitourinary 1Gastrointestinal 1

Conditions

Solid Tumors 1Small Cell Lung Carcinoma 1Rectal Neoplasms 1Prostatic Neoplasms 1Ovarian Neoplasms 1Colorectal Neoplasms 1

Interventions

Cyclophosphamide 389Carboplatin 343Gemcitabine 331pembrolizumab 328Cisplatin 327Paclitaxel 294Radiotherapy 291Docetaxel 285Bevacizumab 249Rituximab 233Capecitabine 221Nivolumab 218Dexamethasone 205Fluorouracil 189fludarabine 177Oxaliplatin 177Pemetrexed 153Doxorubicin 152Irinotecan 147Etoposide 144Leucovorin 143Cytarabine 133Bortezomib 129fludarabine phosphate 128Cetuximab 126Lenalidomide 125Filgrastim 119Erlotinib Hydrochloride 119Temozolomide 111Radiosurgery 110

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Terminated × Interventional × IT-101 × Clear all
NCT03531827 2022-07-12

Combining CRLX101, a Nanoparticle Camptothecin, With Enzalutamide in People With Progressive Metastatic Castration Resistant Prostate Cancer Following Prior Enzalutamide Treatment

National Institutes of Health Clinical Center (CC)

Phase 2 Terminated
4 enrolled 12 charts
Genitourinary

Prostatic Neoplasms

NCT02010567 2020-11-03

Neoadjuvant Chemoradiotherapy With CRLX-101 and Capecitabine for Rectal Cancer

UNC Lineberger Comprehensive Cancer Center

Phase 1/2 Terminated
32 enrolled 18 charts
Gastrointestinal

Rectal Neoplasms, Colorectal Neoplasms

NCT01803269 2020-06-26

Topotecan Hydrochloride or Cyclodextrin-Based Polymer-Camptothecin CRLX101 in Treating Patients With Recurrent Small Cell Lung Cancer

University of Chicago

Phase 2 Terminated
29 enrolled 14 charts
Thoracic

Small Cell Lung Carcinoma

NCT02389985 2020-05-28

A Study of CRLX101(NLG207) in Combination With Weekly Paclitaxel in Patients With Recurrent or Persistent Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer

Lumos Pharma

Phase 1/2 Terminated
30 enrolled
Gynecologic

Ovarian Neoplasms

NCT02648711 2020-05-28

Alternative Dosing for CRLX101(NLG207) Alone, With Avastin and With mFOLFOX6 in Advanced Solid Tumors

Lumos Pharma

Phase 1 Terminated
41 enrolled
Other solid neoplasm

Solid Tumors

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