Clinical Trials

LymphoidOther hematologic neoplasmSarcoma

Uveal Melanoma, Eye Neoplasms, Neoplasms

NCT00924326 2022-01-12

CAR T Cell Receptor Immunotherapy for Patients With B-cell Lymphoma

Phase 1/2 Completed

43 enrolled 19 charts

Leukemia, Lymphoma, Leukemia, Lymphocytic, Chronic, B-Cell, Dendritic Cell Sarcoma, Interdigitating

NCT01369875 2019-12-10

Modified Tumor Infiltrating Lymphocytes for Metastatic Melanoma

2 enrolled 8 charts

Melanoma, Neoplasm Metastasis, Skin Neoplasms

NCT00001564 2019-11-29

A Pilot Study of Tumor-Specific Peptide Vaccination and IL-2 With or Without Autologous T Cell Transplantation in Recurrent Pediatric Sarcomas

30 enrolled

Sarcoma

Rhabdomyosarcoma, Sarcoma, Ewing

NCT02153905 2019-06-17

T Cell Receptor Immunotherapy Targeting MAGE-A3 for Patients With Metastatic Cancer Who Are HLA-A*01 Positive

BreastDermatologicGenitourinaryGynecologic

3 enrolled 14 charts

Urinary Bladder Neoplasms, Breast Neoplasms, Uterine Cervical Neoplasms, Kidney Neoplasms, Melanoma, Neoplasm Metastasis

NCT01814046 2018-10-11

Immunotherapy Using Tumor Infiltrating Lymphocytes for Patients With Metastatic Ocular Melanoma

24 enrolled 13 charts

Uveal Melanoma, Neoplasm Metastasis

NCT00019682 2017-11-20

Aldesleukin With or Without Vaccine Therapy in Treating Patients With Locally Advanced or Metastatic Melanoma

185 enrolled 11 charts

GastrointestinalGenitourinaryGynecologicHead & Neck

Melanoma

NCT02280811 2017-09-06

T Cell Receptor Immunotherapy Targeting HPV-16 E6 for HPV-Associated Cancers

Phase 1/2 Completed

12 enrolled 19 charts

Anus Neoplasms, Uterine Cervical Neoplasms, Neoplasm Metastasis, Oropharyngeal Neoplasms, Penile Neoplasms, Vaginal Neoplasms

NCT00089778 2017-08-01

Vaccine Treatment of Kidney Cancer

11 enrolled 12 charts

Kidney Neoplasms

NCT01271907 2017-08-01

Drosophila-generated CTL

3 enrolled 8 charts

Melanoma, Neoplasms, Skin Neoplasms

NCT00062036 2017-07-02

Cyclophosphamide and Fludarabine Followed By Interleukin-2 Gene-Modified Tumor Infiltrating Lymphocytes in Treating Patients With Metastatic Melanoma

Phase 1/2 Completed

33 enrolled

Melanoma

NCT00096382 2015-10-28

Cyclophosphamide, Fludarabine, and Total-Body Irradiation Followed By Cellular Adoptive Immunotherapy, Autologous Stem Cell Transplantation, and Interleukin-2 in Treating Patients With Metastatic Melanoma

34 enrolled 11 charts

Melanoma

NCT00612222 2015-10-28

Anti-MART-1 F5 Cells Plus ALVAC MART-1 Vaccine to Treat Advanced Melanoma

4 enrolled 9 charts

Melanoma, Skin Neoplasms

NCT00923195 2015-10-28

Radiation, Chemotherapy, Vaccine and Anti-MART-1 and Anti-gp100 Cells for Patients With Metastatic Melanoma

4 enrolled 11 charts

Melanoma, Skin Neoplasms

NCT00924287 2015-10-28

Gene Therapy Using Anti-Her-2 Cells to Treat Metastatic Cancer

1 enrolled 8 charts

Tumor-Agnostic

Neoplasm Metastasis, Neoplasms

NCT01160445 2015-10-28

Phase II Study of Aldesleukin (IL-2) Following the Administration of Zanolimumab (Anti-CD4mAb) in Metastatic Melanoma and Metastatic Renal Cancer

DermatologicGenitourinary

9 enrolled 9 charts

Kidney Neoplasms, Melanoma

NCT01273181 2015-10-28

MAGE-A3/12 Metastatic Cancer Treatment With Anti-MAGE-A3/12 TCR-Gene Engineered Lymphocytes

DermatologicGenitourinary

9 enrolled 13 charts

Carcinoma, Renal Cell, Kidney Neoplasms, Melanoma, Neoplasm Metastasis

NCT00010192 2013-06-06

Rituximab Plus Interleukin-2 in Treating Patients With Hematologic Cancer

LymphoidOther hematologic neoplasm

30 enrolled

Burkitt Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00303836 2013-06-06

Vaccine Therapy With or Without Interleukin-2 After Chemotherapy and an Autologous White Blood Cell Infusion in Treating Patients With Metastatic Melanoma

58 enrolled

Melanoma

NCT00006363 2013-06-04

Combination Chemotherapy With or Without PSC 833, Peripheral Stem Cell Transplantation, and/or Interleukin-2 in Treating Patients With Acute Myeloid Leukemia

Other hematologic neoplasm

720 enrolled

Congenital Abnormalities, Leukemia, Erythroblastic, Acute, Leukemia, Megakaryoblastic, Acute, Leukemia, Monocytic, Acute, Leukemia, Myeloid, Acute, Leukemia, Basophilic, Acute, Leukemia, Eosinophilic, Acute, Leukemia, Myelomonocytic, Acute

NCT00513604 2013-06-03

Phase II Study of Short-Term Cultured Anti-Tumor Autologous Lymphocytes After Lymphocyte-Depleting Chemotherapy in Metastatic Melanoma

158 enrolled 14 charts

Melanoma, Melanoma, Experimental, Neoplasms, Skin Neoplasms

NCT00006033 2013-05-30

Interleukin-2 Gene or Methotrexate in Treating Patients With Recurrent or Refractory Stage III or Stage IV Head and Neck Cancer

Head & Neck

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT00054405 2013-04-09

Interleukin-12 and Interleukin-2 in Treating Patients With Refractory or Recurrent Neuroblastoma

Phase 1 Terminated

40 enrolled

CNS

Neuroblastoma

NCT00002649 2013-02-28

Interleukin-2 or Observation Following Radiation Therapy, Combination Chemotherapy, and Peripheral Stem Cell Transplantation in Treating Patients With Recurrent Non-Hodgkin's Lymphoma

206 enrolled

Lymphoid

Burkitt Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse

NCT00005604 2013-02-01

Interleukin-12 Plus Interleukin-2 in Treating Patients With Advanced Solid Tumors

25 enrolled

Other solid neoplasm

Unspecified Adult Solid Tumor, Protocol Specific

NCT00032188 2013-01-24

Interleukin-2 and Bryostatin 1 in Treating Patients With Advanced Kidney Cancer

65 enrolled

Carcinoma, Renal Cell

NCT00002798 2013-01-16

Combination Chemotherapy With or Without Bone Marrow Transplantation in Treating Children With Acute Myelogenous Leukemia or Myelodysplastic Syndrome

Classical hematologyOther hematologic neoplasm

880 enrolled

Anemia, Refractory, Anemia, Refractory, with Excess of Blasts, Leukemia, Myelomonocytic, Chronic

NCT00005576 2013-01-16

Monoclonal Antibody Therapy With Sargramostim and Interleukin-2 in Treating Children With Neuroblastoma

6 enrolled

CNS

Neuroblastoma

NCT00005949 2013-01-16

Vaccine Plus Interleukin-2 in Treating Patients With Advanced Melanoma

50 enrolled

Melanoma

NCT00052377 2013-01-16

Interleukin-12 and Interleukin-2 in Treating Patients With Mycosis Fungoides

46 enrolled

DermatologicLymphoid

Mycosis Fungoides, Sezary Syndrome, Lymphoma, T-Cell, Cutaneous

NCT00509496 2013-01-15

Phase II Study of Metastatic Melanoma With Lymphodepleting Conditioning and Anti-gp100:154-162 TCR Gene Engineered Lymphocytes

21 enrolled 11 charts

Melanoma, Skin Neoplasms

NCT00509288 2012-12-28

Phase II Study of Metastatic Melanoma With Lymphodepleting Conditioning and Infusion of Anti-MART-1 F5 TCR-Gene-Engineered Lymphocytes

24 enrolled 11 charts

Melanoma, Skin Neoplasms

NCT00001832 2012-12-21

Lymphocyte Re-infusion During Immune Suppression to Treat Metastatic Melanoma

170 enrolled 23 charts

BreastDermatologic

Breast Neoplasms, Melanoma, Neoplasm Metastasis

NCT00328861 2012-11-05

Natural Killer Cells Plus IL-2 Following Chemotherapy to Treat Advanced Melanoma or Kidney Cancer

DermatologicGenitourinary

8 enrolled 8 charts

Kidney Neoplasms, Melanoma

NCT00091611 2012-10-26

Cultured White Cells Plus Interleukin-2 to Treat Advanced Kidney Cancer

Phase 1 Terminated

3 enrolled

Carcinoma, Renal Cell, Kidney Neoplasms

NCT00059475 2012-10-23

Peptide Vaccination for Patients at High Risk for Recurrent Melanoma

138 enrolled 16 charts

Melanoma

NCT00314106 2012-10-18

Chemotherapy, Irradiation, Cell Infusions, and Interleukin-2 to Treat Metastatic Melanoma

26 enrolled 11 charts

Melanoma

NCT00080353 2012-06-14

Vaccine Treatment in Combination With IL-2 and Treated Lymphocytes for Advanced Melanoma

58 enrolled

Melanoma

NCT00393029 2011-08-15

Phase II Study of Metastatic Cancer That Overexpresses P53 Using Lymphodepleting Conditioning Followed by Infusion of Anti-P53 TCR-Gene Engineered Lymphocytes

12 enrolled 10 charts

Carcinoma, Renal Cell, Neoplasm Metastasis, Neoplasms

NCT00001430 2008-03-04

A Randomized Study of EPOCH II Versus EPOCH II and Immunotherapy in Lymphomas

49 enrolled

Lymphoid

Hodgkin Disease, Lymphoma, Non-Hodgkin

NCT00001440 2008-03-04

Autologous T-Cell Transplantation and the Immunotherapy of Residual Disease in Breast Cancer: Pilot Study of Vaccine-Driven T-Cell Expansion in Patients Treated With Dose-Intensive Chemotherapy

51 enrolled

Breast

Breast Neoplasms, Neoplasm Metastasis

NCT00001475 2008-03-04

Home Treatment of HIV-Infected Patients With Interleukin-2 With or Without a Tumor Necrosis Factor Antagonist

85 enrolled

Acquired Immunodeficiency Syndrome, HIV Infections

NCT00001705 2008-03-04

Immunization of Patients With Metastatic Melanoma Using the GP100 Peptide Preceded by an Endoplasmic Reticulum Insertion Signal Sequence

141 enrolled

Melanoma, Neoplasm Metastasis, Neoplasms

NCT00001535 2008-02-08

Twins Study of Gene Therapy for HIV Infection