Clinical Trials Browser

NCT04924192 2026-04-13

A Clinical Study of TQB3616 Capsules Combined With Anlotinib Hydrochloride Capsules or Standard Chemotherapy Second-line and Above in the Treatment of Advanced Lung Cancer

Phase 2 Terminated

21 enrolled

Advanced Lung Carcinoma

NCT05678257 2025-09-12

A Study of NUC-3373 in Combination With Other Agents in Patients With Colorectal Cancer

Phase 2 Terminated

180 enrolled 16 charts

Gastrointestinal

Colonic Neoplasms, Neoplasm Metastasis, Neoplasms, Colorectal Neoplasms

NCT04141995 2025-08-07

FOLFIRINOX With Digoxin in Patients With Resectable Pancreatic Cancer

Phase 2 Terminated

11 enrolled

Gastrointestinal

Pancreatic Neoplasms

NCT05330429 2025-07-01

ELEVATE CRC

Phase 2 Terminated

77 enrolled 22 charts

Gastrointestinal

Colorectal Neoplasms

NCT05461794 2025-06-13

Study To Investigate the Efficacy and Safety of Sitravatinib in Combination With Tislelizumab in Participants With Esophageal Squamous Cell Carcinoma

Phase 2 Terminated

96 enrolled 17 charts

Gastrointestinal

Esophageal Squamous Cell Carcinoma

NCT03387592 2025-03-10

SENECA

Phase 2 Terminated

53 enrolled

Endocrine

Carcinoma, Neuroendocrine

NCT03822936 2025-02-13

PIOPPO

Phase 2 Terminated

30 enrolled

Gastrointestinal

Pancreatic Neoplasms

NCT03117972 2025-02-05

CLavSyn

Phase 2 Terminated

54 enrolled

Gastrointestinal

Colorectal Neoplasms

NCT02485834 2025-01-20

FDG-PET Directed Treatment in Improving Response in Patients With Locally Advanced Stomach or Gastroesophageal Junction Cancer

Phase 2 Terminated

5 enrolled 11 charts

Gastrointestinal

Stomach Neoplasms

NCT05546411 2024-12-17

A Trial of NIS793 With FOLFIRINOX in Pancreatic Cancer

Phase 2 Terminated

8 enrolled 11 charts

Gastrointestinal

Pancreatic Neoplasms

NCT05039944 2024-07-18

SI-B001 as a Single Agent or in Combination With Chemotherapy in the Treatment of Digestive System Malignancies

Phase 2 Terminated

7 enrolled

Gastrointestinal

Colorectal Neoplasms

NCT02842580 2024-07-10

HIGH-LIGHT

Phase 2 Terminated

21 enrolled 12 charts

Gastrointestinal

Neoplasm Metastasis, Neoplasms, Colorectal Neoplasms

NCT05148195 2024-03-13

A Phase II Study of Envofolimab and BD0801 With/Without Chemotherapy in Patients With Advanced Solid Tumors

Phase 2 Terminated

86 enrolled

Other solid neoplasm

Advanced Solid Tumor

NCT01897454 2023-12-05

Gemcitabine Hydrochloride, and Radiation Therapy in Patients With Borderline Resectable Pancreatic Cancer

Phase 2 Terminated

23 enrolled 14 charts

Gastrointestinal

Pancreatic Neoplasms

NCT03251417 2023-02-01

Apatinib and Irinotecan Combination Treatment in Unresectable or Metastatic Esophageal Squamous Cell Carcinoma

Phase 2 Terminated

11 enrolled

Gastrointestinal

Esophageal Squamous Cell Carcinoma

NCT03099265 2022-10-27

Neoadjuvant Modified FOLFIRINOX and Stereotactic Body Radiation Therapy in Borderline Resectable Pancreatic Adenocarcinoma

Phase 2 Terminated

9 enrolled 14 charts

Gastrointestinal

Pancreatic Neoplasms

NCT00314353 2021-10-06

Study of Bevacizumab Combined With Capecitabine and Either Oxaliplatin or Irinotecan as First Course of Treatment for Patients With Colorectal Cancer That Has Spread Beyond the Colon

Phase 2 Terminated

7 enrolled 5 charts

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT03368859 2021-02-09

A Study of ABT-165 Plus FOLFIRI vs Bevacizumab Plus FOLFIRI in Subjects With Metastatic Colorectal Cancer Previously Treated With Fluoropyrimidine, Oxaliplatin and Bevacizumab

Phase 2 Terminated

70 enrolled 12 charts

Gastrointestinal

Intestinal Neoplasms, Neoplasms, Colorectal Neoplasms

NCT01367275 2020-09-03

Irinotecan Plus Brivanib in Metastatic Colorectal Cancer (CRC) Enriched for Elevated Levels of Plasma FGF

Phase 2 Terminated

8 enrolled 5 charts

Gastrointestinal

Acrocephalosyndactylia, Colorectal Neoplasms

NCT02405585 2020-05-28

Immunotherapy and SBRT Study in Borderline Resectable Pancreatic Cancer

Phase 2 Terminated

10 enrolled

Gastrointestinal

Pancreatic Neoplasms

NCT01609231 2020-05-04

MK-0646-025

Phase 2 Terminated

11 enrolled 8 charts

Gastrointestinal

Rectal Neoplasms

NCT02275806 2019-08-21

Cisplatin/Irinotecan With Concurrent Radiation for Inoperable NSCLC

Phase 2 Terminated

4 enrolled

Thoracic

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT01479465 2019-04-17

Efficacy and Safety of Simtuzumab (SIM) With FOLFIRI as Second Line Treatment in Colorectal Adenocarcinoma

Phase 2 Terminated

266 enrolled 15 charts

Gastrointestinal

Neoplasms, Colorectal Neoplasms

NCT01760252 2019-03-15

Neoadjuvant CAPOXIRI Chemotherapy in the Treatment of Pancreatic Adenocarcinoma Protocol

Phase 2 Terminated

17 enrolled

Gastrointestinal

Pancreatic Neoplasms

NCT00465907 2019-02-11

Study of Weekly Paclitaxel, Carboplatin and Irinotecan to Treat Lung Cancer

Phase 2 Terminated

7 enrolled

Thoracic

Lung Neoplasms

NCT01925274 2019-01-08

A Study Of PF-05212384 Plus Irinotecan Vs Cetuximab Plus Irinotecan In Patients With KRAS And NRAS Wild Type Metastatic Colorectal Cancer

Phase 2 Terminated

19 enrolled 32 charts

Gastrointestinal

Colonic Neoplasms, Colorectal Neoplasms

NCT00100828 2018-12-06

Irinotecan in Treating Patients With Metastatic or Inoperable Thyroid Cancer

Phase 2 Terminated

6 enrolled 4 charts

Head & Neck

Head and Neck Neoplasms, Thyroid Neoplasms, Carcinoma, Medullary

NCT00276744 2018-10-24

Individualized Drug Treatment for Treating Patients With Pancreatic Cancer

Phase 2 Terminated

249 enrolled 4 charts

Gastrointestinal

Pancreatic Neoplasms

NCT02508077 2018-08-16

FOLFIRI and Panitumumab in Treating Patients With RAS and BRAF Wild-Type Metastatic Colorectal Cancer

Phase 2 Terminated

1 enrolled 4 charts

Gastrointestinal

Colorectal Neoplasms

NCT01608464 2018-08-10

Pre-op Chemo-RT w/CDDP/5FU vs Chemo w/ Docetaxel/Irinotecan in PET Non Responder Resectable Esophagus Cancer

Phase 2 Terminated

170 enrolled

Gastrointestinal

Esophageal Neoplasms

NCT01935947 2018-07-27

Azacitidine and Entinostat Before Chemotherapy in Treating Patients With Advanced Non-small Cell Lung Cancer

Phase 2 Terminated

17 enrolled 10 charts

Thoracic

Carcinoma, Non-Small-Cell Lung

NCT02241551 2018-07-26

Phase II Neoadjuvant Chemotheraphy (Gemcitabine and Nab-Paclitaxel vs. mFOLFIRINOX) and Sterotatic Body Radiation Therapy for Borderline Resectable Pancreatic Cancer

Phase 2 Terminated

2 enrolled 7 charts

Tumor-Agnostic

Neoplasms

NCT00089102 2018-07-16

Gemcitabine and Irinotecan in Treating Patients With Locally Advanced Unresectable or Metastatic Kidney Cancer

Phase 2 Terminated

9 enrolled 8 charts

Genitourinary

Carcinoma, Renal Cell, Kidney Neoplasms

NCT02345460 2018-07-13

Preoperative Folfirinox for Resectable Pancreatic Adenocarcinoma - A Phase II Study

Phase 2 Terminated

1 enrolled 5 charts

Gastrointestinal

Pancreatic Neoplasms

NCT00089128 2018-07-12

Gemcitabine and Irinotecan in Treating Patients With Locally Advanced or Metastatic Bladder Cancer

Phase 2 Terminated

16 enrolled 4 charts

Genitourinary

Urinary Bladder Neoplasms

NCT00845039 2018-07-02

FC-4

Phase 2 Terminated

4 enrolled 9 charts

Gastrointestinal

Colonic Neoplasms, Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00642603 2018-03-29

A Study of Xeloda (Capecitabine) in Combination With Avastin + Short Course Chemotherapy in Patients With Metastatic Colorectal Cancer

Phase 2 Terminated

41 enrolled 6 charts

Gastrointestinal

Colorectal Neoplasms

NCT01359007 2018-03-09

FOLFIRINOX in Patients With Inoperable Pancreatic Cancer

Phase 2 Terminated

5 enrolled 7 charts

Gastrointestinal

Adenocarcinoma of Pancreas

NCT00256269 2018-01-26

Oxaliplatin and Irinotecan in Recurrent or Metastatic Esophageal and Gastroesophageal (GE) Junction Carcinoma

Phase 2 Terminated

4 enrolled

Gastrointestinal

Esophageal Neoplasms

NCT00848783 2018-01-08

Irinotecan/Cisplatin, Potentially Curative Surgery With or Without Floxuridine, Followed by Capecitabine for Stomach and Gastro-esophageal Junction (GEJ) Cancers

Phase 2 Terminated

8 enrolled 9 charts

Gastrointestinal

Esophageal Neoplasms, Stomach Neoplasms

NCT01313884 2017-11-24

Cyclophosphamide, Doxorubicin, Vincristine w/ Irinotecan and Temozolomide in Ewings Sarcoma

Phase 2 Terminated

3 enrolled 7 charts

Sarcoma

Bone Neoplasms, Sarcoma, Ewing

NCT01688336 2017-10-06

FOLFIRINOX for Unresectable Locally Advanced and Borderline Resectable Pancreatic Cancer

Phase 2 Terminated

9 enrolled 14 charts

Gastrointestinal

Pancreatic Neoplasms

NCT01765582 2017-09-18

STEAM

Phase 2 Terminated

280 enrolled 15 charts

Gastrointestinal

Colorectal Neoplasms

NCT02316496 2017-08-01

REGAIN

Phase 2 Terminated

2 enrolled

Tumor-Agnostic

Neoplasm Metastasis, Neoplasms

NCT00808899 2017-05-30

Neuroblastoma Protocol 2008: Therapy for Children With Advanced Stage High Risk Neuroblastoma

Phase 2 Terminated

4 enrolled 5 charts

CNS

Neuroblastoma

NCT00449163 2017-05-11

Combination Chemotherapy and Bevacizumab in Treating Patients With Stage IV Colorectal Cancer

Phase 2 Terminated

25 enrolled 10 charts

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00588900 2017-04-05

Irinotecan and Cediranib in Treating Patients With Metastatic Colorectal Cancer That Did Not Respond to Previous Oxaliplatin, Fluoropyrimidine, and Bevacizumab

Phase 2 Terminated

5 enrolled 5 charts

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00127036 2017-03-23

Trial for Microarray Analysis of Colon Cancer Outcome-A (MACCO-A)

Phase 2 Terminated

65 enrolled 8 charts

Gastrointestinal

Adenocarcinoma, Colonic Neoplasms, Rectal Neoplasms

NCT00360828 2017-03-23

Phase II Study of Irinotecan HCI for Recurrent Anaplastic Astrocytomas, Mixed Malignant Gliomas, and Oligodendrogliomas

Phase 2 Terminated

10 enrolled 6 charts

CNS

Astrocytoma, Brain Neoplasms, Glioma, Neurologic Manifestations, Oligodendroglioma

NCT00040391 2016-12-01

A Trial of an Investigational Drug for the Prevention of Diarrhea Associated With Irinotecan/5FU/Leucovorin Chemotherapy in Previously Untreated Metastatic Colorectal Cancer

Phase 2 Terminated

Gastrointestinal

Diarrhea, Colorectal Neoplasms