Clinical Trials Browser

Phase 3 × Completed × Irinotecan × Clear all

NCT05153239 2026-05-13

Clinical Trial of Lurbinectedin as Single-agent or in Combination With Irinotecan Versus Topotecan or Irinotecan in Patients With Relapsed Small-cell Lung Cancer (LAGOON)

Phase 3 Completed

Small Cell Lung Carcinoma

NCT04697628 2026-02-24

innovaTV 301

Phase 3 Completed

502 enrolled 18 charts 1 FDA

Uterine Cervical Neoplasms

NCT02314182 2025-12-19

GRECCAR8

Phase 3 Completed

Gastrointestinal

Rectal Neoplasms

NCT02967289 2025-11-17

IROCAS

Phase 3 Completed

Gastrointestinal

Colonic Neoplasms, Neoplasms

NCT02605265 2025-08-28

CinClare

Phase 3 Completed

Gastrointestinal

Locally Advanced Rectal Cancer

NCT03206151 2025-05-23

CMAB009 Combined With FOLFIRI First-line Treatment in Patients With RAS/BRAF Wild-type, Metastatic Colorectal Cancer

Phase 3 Completed

Gastrointestinal

Colorectal Neoplasms

NCT03750669 2025-05-13

Sequential Use of AG and mFOLFIRINOX as Neoadjuvant Chemotherapy for Resectable Pancreatic Cancer

Phase 3 Completed

Gastrointestinal

Pancreatic Neoplasms

NCT02934529 2025-04-16

AIO-KRK-0114

Phase 3 Completed

Gastrointestinal

Colorectal Neoplasms

NCT02162563 2025-02-06

CAIRO5

Phase 3 Completed

Gastrointestinal

Colorectal Neoplasms

NCT03941093 2024-11-05

LAPIS

Phase 3 Completed

284 enrolled 14 charts

Gastrointestinal

Pancreatic Cancer Non-resectable

NCT03430843 2024-10-26

A Study of Tislelizumab (BGB-A317) Versus Chemotherapy as Second Line Treatment in Participants With Advanced Esophageal Squamous Cell Carcinoma

Phase 3 Completed

512 enrolled 27 charts

Gastrointestinal

Esophageal Squamous Cell Carcinoma, Neoplasm Metastasis

NCT03099382 2024-01-22

Study of SHR-1210 Versus Investigator's Choice of Chemotherapy for Participants With Advanced Esophageal Cancer

Phase 3 Completed

457 enrolled 9 charts

Gastrointestinal

Esophageal Neoplasms

NCT02539537 2024-01-09

NEOPAN

Phase 3 Completed

Gastrointestinal

Carcinoma, Pancreatic Neoplasms

NCT02928224 2023-12-21

BEACON CRC

Phase 3 Completed

702 enrolled 82 charts 1 FDA

Gastrointestinal

Colorectal Neoplasms

NCT02753127 2023-11-15

CanStem303C

Phase 3 Completed

1,253 enrolled 18 charts

Gastrointestinal

Colonic Diseases, Digestive System Diseases, Digestive System Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Glandular and Epithelial, Rectal Diseases, Colorectal Neoplasms

NCT03933449 2023-03-29

KEYNOTE-181

Phase 3 Completed

123 enrolled 25 charts

Gastrointestinal

Parkinson Disease 4, Autosomal Dominant Lewy Body, Esophageal Neoplasms

NCT02564263 2023-03-13

KEYNOTE-181

Phase 3 Completed

628 enrolled 27 charts 1 FDA

Gastrointestinal

Parkinson Disease 4, Autosomal Dominant Lewy Body, Esophageal Neoplasms

NCT00354835 2023-01-31

Combination Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Rhabdomyosarcoma

Phase 3 Completed

481 enrolled 21 charts

Rhabdomyosarcoma, Sarcoma

NCT03231722 2023-01-05

TRIPLETE

Phase 3 Completed

Gastrointestinal

Colorectal Neoplasms

NCT03504423 2023-01-03

Study Evaluating Efficacy and Safety of FFX Versus Combination of CPI-613 With mFFX in Patients With Metastatic Adenocarcinoma of the Pancreas

Phase 3 Completed

528 enrolled 11 charts

Gastrointestinal

Pancreatic Cancer Metastatic

NCT00642577 2022-12-22

A Study of Avastin (Bevacizumab) in Combination With Chemotherapy in Chinese Patients With Metastatic Colorectal Cancer.

Phase 3 Completed

Gastrointestinal

Colorectal Neoplasms

NCT01926197 2022-10-28

Phase 3 Study of FOLFIRINOX (mFFX) +/- SBRT in Locally Advanced Pancreatic Cancer

Phase 3 Completed

27 enrolled 15 charts

Gastrointestinal

Pancreatic Neoplasms

NCT03665441 2022-10-18

Trybeca-1

Phase 3 Completed

512 enrolled 19 charts

Neoplasms

NCT00389870 2022-06-01

Irinotecan With or Without Panitumumab or Cyclosporine in Treating Patients With Advanced or Metastatic Colorectal Cancer That Did Not Respond to Fluorouracil

Phase 3 Completed

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00005979 2021-02-17

Combination Chemotherapy With or Without Irinotecan in Treating Patients With Stage III Colon Cancer

Phase 3 Completed

Gastrointestinal

Colonic Neoplasms, Colorectal Neoplasms

NCT02625623 2020-11-24

Avelumab in Third-Line Gastric Cancer (JAVELIN Gastric 300)

Phase 3 Completed

371 enrolled 18 charts

Gastrointestinal

Recurrence, Stomach Neoplasms

NCT00079274 2020-05-13

Comparison of Combination Chemotherapy Regimens With or Without Cetuximab in Treating Patients Who Have Undergone Surgery For Stage III Colon Cancer

Phase 3 Completed

3,397 enrolled 24 charts

Gastrointestinal

Colonic Neoplasms

NCT00265850 2020-05-07

Cetuximab and/or Bevacizumab Combined With Combination Chemotherapy in Treating Patients With Metastatic Colorectal Cancer

Phase 3 Completed

2,334 enrolled 9 charts

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00003594 2020-04-29

Combination Chemotherapy in Treating Patients With Advanced Colorectal Cancer

Phase 3 Completed

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00354744 2020-01-29

High-Dose Combination Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Metastatic Rhabdomyosarcoma or Ectomesenchymoma

Phase 3 Completed

109 enrolled 12 charts

Malignant mesenchymal tumor, Rhabdomyosarcoma, Sarcoma

NCT00941655 2019-11-13

Prospective Randomized Trial Comparing Gastrectomy, Metastasectomy Plus Systemic Therapy Versus Systemic Therapy Alone: GYMSSA Trial

Phase 3 Completed

15 enrolled 18 charts

Gastrointestinal

Carcinoma, Hepatocellular, Stomach Neoplasms

NCT01183780 2019-09-25

A Study in Second Line Metastatic Colorectal Cancer

Phase 3 Completed

1,072 enrolled 17 charts

Gastrointestinal

Colorectal Neoplasms

NCT01996306 2019-01-08

AXEPT

Phase 3 Completed

Gastrointestinal

Digestive System Neoplasms, Gastrointestinal Neoplasms, Intestinal Neoplasms, Neoplasm Metastasis, Colorectal Neoplasms

NCT00068692 2018-12-04

Comparison of Adjuvant Chemotherapy Regimens in Treating Stage II/III Rectal Cancer

Phase 3 Completed

225 enrolled 12 charts

Gastrointestinal

Rectal Neoplasms

NCT00045162 2018-07-31

S0124: Cisplatin Combined With Irinotecan or Etoposide For Extensive-Stage Small Cell Lung Cancer

Phase 3 Completed

671 enrolled 10 charts

Lung Neoplasms

NCT01593228 2017-09-19

Treatment Extension Study for Patients Who Have Previously Participated and Have Benefited From Iniparib in a Clinical Trial

Phase 3 Completed

Other solid neoplasm

Solid Tumors

NCT03067792 2017-03-01

FOLFIRI Versus Docetaxel and Cisplatin as a Second-line Chemotherapy After Failure of First-line Chemotherapy in Advanced Gastric Cancer

Phase 3 Completed

Gastrointestinal

Inoperable Gastric Cancer

NCT00154102 2017-01-30

CRYSTAL

Phase 3 Completed

1,221 enrolled 24 charts

Gastrointestinal

Colorectal Neoplasms

NCT01670721 2016-11-28

AFEQT

Phase 3 Completed

175 enrolled 6 charts

Gastrointestinal

Colorectal Cancer Metastatic

NCT00144989 2016-09-22

A Study Comparing Irinotecan and Cisplatin (IP) With Etoposide and Cisplatin (EP) Following EP/TRT for LD-SCLC

Phase 3 Completed

Small Cell Lung Carcinoma

NCT00006103 2016-07-06

Combination Chemotherapy in Treating Patients With Colorectal Cancer

Phase 3 Completed

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00303771 2016-05-30

Combination Chemotherapy as First-Line Therapy in Treating Older Patients With Metastatic Colorectal Cancer That Cannot Be Removed By Surgery

Phase 3 Completed

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00126256 2015-08-13

Trial Comparing Two Strategies of Chemotherapy for Metastatic Colorectal Cancer

Phase 3 Completed

Gastrointestinal

Neoplasm Metastasis, Colorectal Neoplasms

NCT01030042 2015-07-15

COMETS

Phase 3 Completed

Gastrointestinal

Neoplasm Metastasis, Colorectal Neoplasms

NCT00457691 2015-03-30

Study Of FOLFIRI Chemotherapy With Or Without Sunitinib In Patients With Metastatic Colorectal Cancer

Phase 3 Completed

768 enrolled 15 charts

Gastrointestinal

Colorectal Neoplasms

NCT00719797 2015-03-11

TRIBE

Phase 3 Completed

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT01219920 2015-03-11

FOLFOXIRI Compared With FOLFIRI for Metastatic Colorectal Cancer

Phase 3 Completed

Gastrointestinal

Colorectal Neoplasms

NCT00008060 2013-12-19

Combination Chemotherapy in Treating Patients With Unresectable Metastatic Colorectal Cancer

Phase 3 Completed

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00012389 2013-12-19

Irinotecan With or Without Oxaliplatin in Treating Patients With Metastatic Colorectal Cancer

Phase 3 Completed

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00349492 2013-12-04

A Study Comparing Etoposide/Cisplatin With Irinotecan/Cisplatin to Treat Extensive Disease Small Lung Cancer

Phase 3 Completed

Small Cell Lung Carcinoma