Clinical Trials

56 enrolled

Neoplasm Metastasis

NCT05357820 2024-11-21

A Study of AB-106 in Chinese Healthy Adult Men Evaluated the Effects of Itraconazole and Rifampicin on AB-106 PK

56 enrolled

Solid Tumor

NCT03994211 2024-10-26

Study to Investigate the Effect of Rifampin and Itraconazole on the Action of Pamiparib in Participants With Cancer

25 enrolled 33 charts

Solid Tumor

NCT06348888 2024-06-20

A Study to Learn About How Itraconazole and Carbamazepine Affect the Level of BAY2927088 in the Blood When These Drugs Are Taken Together by Healthy Participants

30 enrolled

Thoracic

Carcinoma, Non-Small-Cell Lung

NCT05573724 2024-06-18

Drug-drug Interaction Study With AZD5305 and Itraconazole in Patients With Advanced Solid Malignancies

16 enrolled

Neoplasms

NCT05602597 2024-03-06

HMPL-689 Drug Interaction Study With CYP3A Inhibitor/CYP2C9 Inhibitor/CYP3A Inducer/PPI

59 enrolled

Lymphoma, Recurrence

NCT00798135 2023-12-21

A Pilot Trial of Itraconazole Pharmacokinetics in Patients With Metastatic Breast Cancer

Phase NA Completed

13 enrolled 11 charts

Breast

Breast Neoplasms, Neoplasm Metastasis

NCT03383692 2023-12-11

Study of DS-8201a for Participants With Advanced Solid Malignant Tumors

40 enrolled 20 charts

Neoplasm Metastasis, Neoplasms

NCT01772563 2023-09-01

Investigation of Potential Drug-drug Interaction of Volasertib With Itraconazole in Patients With Various Tumours

28 enrolled 10 charts

Neoplasms

NCT05720767 2023-03-01

HMPL-523 CYP3A/P-gp Inhibitor and CYP Inducer Study

28 enrolled

Lymphoma, Recurrence

NCT00585195 2023-02-08

PROFILE 1001

596 enrolled 81 charts

Lymphoma, Large-Cell, Anaplastic

NCT05048615 2023-01-25

Low-dose Venetoclax and Azacitidine as Front-line Therapy in Newly Diagnosed AML

Other hematologic neoplasm

15 enrolled

Leukemia, Myeloid, Acute

NCT05551897 2023-01-06

A Study to Assess the Pharmacokinetics of Camizestrant (AZD9833) When Administered Alone and in Combination With Itraconazole

14 enrolled

Breast

Breast Neoplasms

NCT02770378 2021-10-05

A Proof-of-concept Clinical Trial Assessing the Safety of the Coordinated Undermining of Survival Paths by 9 Repurposed Drugs Combined With Metronomic Temozolomide (CUSP9v3 Treatment Protocol) for Recurrent Glioblastoma

Phase 1/2 Completed

10 enrolled

CNS

Glioblastoma

NCT04584515 2021-08-24

IMP4297 DDI (Drug-Drug Interaction)Trial in Healthy Male Volunteers

32 enrolled

Solid Tumor

NCT03077607 2021-06-30

A Study to Evaluate the Effect of Itraconazole and Rifampin on the Pharmacokinetics of Talazoparib in Patients With Advanced Solid Tumors

36 enrolled 28 charts

Phase EARLY_PHASE1 Completed

Advanced Solid Tumors

NCT02357836 2021-05-03

Neoadjuvant Itraconazole in Non-small Cell Lung Cancer

13 enrolled 12 charts

Thoracic

Carcinoma, Non-Small-Cell Lung

NCT04712396 2021-04-09

A Study to Assess How Itraconazole Affects the Uptake and Elimination of Capivasertib in the Body

Phase EARLY_PHASE1 Completed

11 enrolled

BreastGenitourinary

Healthy Volunteers (Intended Indication: Metastatic Patients With Triple Negative or HR+ Breast Cancer, or Hormone Sensitive Prostate Cancer)

NCT03081702 2021-04-02

A Study of the Safety, Tolerability and Effectiveness of Hydroxychloroquine and Itraconazole in Platinum-resistant Epithelial Ovarian Cancer

Phase 1/2 Completed

13 enrolled

Gynecologic

Platinum-resistant Epithelial Ovarian Cancer

NCT02120677 2020-12-16

Topical Itraconazole in the Treatment of Basal Cell Carcinoma

5 enrolled

Carcinoma, Basal Cell, Skin Neoplasms

NCT02253420 2020-12-14

COPANLISIB (BAY80-6946) Drug-drug Interaction and Cardiovascular Safety Study in Advanced Solid Tumor and Non-Hodgkin's Lymphoma Patients

51 enrolled

Lymphoma, Non-Hodgkin

NCT02706535 2020-11-16

A Cross-over Study to Evaluate the Effect of Itraconazole and Rifampicin on the Pharmacokinetics (PK) of GSK525762 in Healthy Female Subjects of Non Child Bearing Potential

29 enrolled

BreastCNSDermatologicGenitourinaryGynecologicLymphoidMyeloidOther hematologic neoplasmPlasma cellSarcoma

Neoplasms

NCT00079222 2020-08-03

Voriconazole Compared With Itraconazole in Preventing Fungal Infections in Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation

Phase NA Completed

Pdgfra-Associated Chronic Eosinophilic Leukemia, Congenital Abnormalities, Carcinoma, Ovarian Epithelial, Blast Crisis, Breast Neoplasms, Burkitt Lymphoma, Hodgkin Disease, Infections, Leukemia, Hairy Cell, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Multiple Myeloma, Mycosis Fungoides, Myeloproliferative Disorders, Neoplasms, Wilms Tumor, Neuroblastoma, Recurrence, Sezary Syndrome, Testicular Neoplasms, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myeloid, Accelerated Phase, Leukemia, Myeloid, Chronic-Phase, Leukemia, Neutrophilic, Chronic, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, T-Cell, Cutaneous, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Leukemia, Myelomonocytic, Juvenile, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative, Dendritic Cell Sarcoma, Interdigitating, Primary Myelofibrosis

NCT02824042 2020-07-31

Thorough ECG (Electrocardiogram) and Drug Interaction Study With Anetumab Ravtansine and Itraconazole

63 enrolled

Medical Oncology

NCT02608034 2020-02-12

A Study to Investigate the Effect of Itraconazole and Rifampin on Pharmacokinetics (PK) of Vemurafenib at Steady State

32 enrolled

Melanoma

NCT01787331 2020-02-05

Itraconazole in Treating Patients With Biochemically Relapsed Prostate Cancer

21 enrolled 16 charts

Genitourinary

Prostatic Neoplasms

NCT04121910 2020-01-23

A Study to Evaluate the Amount of Drug That Becomes Available in the Blood Circulation When Savolitinib is Administered Alone and in Combination With Itraconazole

16 enrolled

Solid Tumour

NCT02259010 2019-09-20

A Study to Evaluate the Effect of Itraconazole on the Pharmacokinetics of Alisertib in Participants With Advanced Solid Tumors or Relapsed/Refractory Lymphoma

24 enrolled 26 charts

Phase EARLY_PHASE1 Completed

Lymphoma

NCT02735356 2019-04-11

Topical Itraconazole in Treating Patients With Basal Cell Cancer

9 enrolled

Carcinoma, Basal Cell

NCT02122770 2019-01-07

Effects of Fluconazole and Itraconazole CYP3A-Mediated Inhibition on the Pharmacokinetics, Safety, and Tolerability of MLN4924 in Participants With Advanced Solid Tumors

51 enrolled 30 charts

Advanced Solid Tumors

NCT01108094 2018-11-13

Pilot Biomarker Trial to Evaluate the Efficacy of Itraconazole in Patients w/ Basal Cell Carcinomas

29 enrolled 13 charts

Carcinoma, Basal Cell, Skin Neoplasms

NCT03346837 2018-02-28

A Study to Evaluate the Effect of 2 Drugs on the Pharmacokinetics of BMS-986205 in Healthy Subjects

53 enrolled

Malignancies Multiple

NCT00887458 2017-10-16

A Two-dose Level Clinical Trial of Itraconazole in Patients With Metastatic Prostate Cancer Who Have Had Disease Progression While on Hormonal Therapy

MyeloidOther hematologic neoplasm

46 enrolled 8 charts

Genitourinary

Prostatic Neoplasms

NCT00045942 2017-08-11

PKC412 in Participants With Acute Myeloid Leukemia or With Myelodysplastic Syndrome (CPKC412A2104 Core); and PKC412 in Participants With Acute Myeloid Leukemia or With Myelodysplastic Syndrome With Either Wild Type or Mutated FMS-like Tyrosine Kinase 3 (FLT3) (CPKC412A2104E1 and CPKC412A2104E2)

Phase 1/2 Completed

144 enrolled 48 charts

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute

NCT02836171 2017-02-27

Effect of Itraconazole on the Pharmacokinetics of Apatinib

20 enrolled

Neoplasms

NCT02401295 2017-02-23

ATRA, Celecoxib, and Itraconazole as Maintenance

1 enrolled

Plasma cell

Multiple Myeloma

NCT01900028 2016-10-17

To Assess the Effect of Itraconazole (a CYP3A4 Inhibitor) on the Pharmacokinetics of Olaparib, and the Effect of Olaparib on QT Interval Following Oral Dosing of a Tablet Formulation to Patients With Advanced Solid Tumours

85 enrolled

Neoplasms

NCT02457351 2016-05-23

Roniciclib (BAY 1000394) Drug-Drug Interaction (DDI) Study

14 enrolled

Medical Oncology

NCT02093728 2015-06-30

To Assess the Effect of Itraconazole and Fluconazole on the Pharmacokinetics of Selumetinib in Healthy Male Volunteers

26 enrolled

Solid Tumours

NCT01409018 2013-11-19

Pharmacokinetics of Itraconazole in Pediatric Cancer Patients