Announcements Trials
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Phase

Phase 1 5Phase 2 3

Status

Completed 3

Sponsor Class

OTHER 2INDUSTRY 1

Study Type

Interventional 3

Sponsor

Cancer Type

Plasma cell 1Myeloid 1Breast 1

Conditions

Triple Negative Breast Neoplasms 1Primary Myelofibrosis 1Polycythemia Vera 1Multiple Myeloma 1Breast Neoplasms 1

Interventions

Cyclophosphamide 741Cisplatin 688Gemcitabine 641Bevacizumab 616Carboplatin 605Paclitaxel 601Docetaxel 565Radiotherapy 536Fluorouracil 405Oxaliplatin 387Rituximab 369Doxorubicin 361Capecitabine 342Filgrastim 333Etoposide 330Dexamethasone 312Irinotecan 309pembrolizumab 282Leucovorin 274Cetuximab 268Cytarabine 242Erlotinib Hydrochloride 231Nivolumab 228Prednisone 227Trastuzumab 225Vincristine 221Bortezomib 221Methotrexate 207Pemetrexed 199fludarabine phosphate 195

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Phase 2 × Completed × LCL161 × Clear all
NCT02098161 2023-06-06

LCL161 in Treating Patients With Primary Myelofibrosis, Post-Polycythemia Vera Myelofibrosis, or Post-Essential Thrombocytosis Myelofibrosis

M.D. Anderson Cancer Center

Phase 2 Completed
50 enrolled 11 charts
Myeloid

Polycythemia Vera, Primary Myelofibrosis

NCT01955434 2019-09-10

SMAC Mimetic LCL161 Alone or With Cyclophosphamide in Treating Patients With Relapsed or Refractory Multiple Myeloma

Mayo Clinic

Phase 2 Completed
25 enrolled 6 charts
Plasma cell

Multiple Myeloma

NCT01617668 2016-10-17

A Randomized, Phase 2, Neoadjuvant Study of Weekly Paclitaxel With or Without LCL161 in Patients With Triple Negative Breast Cancer

Novartis

Phase 2 Completed
209 enrolled 20 charts
Breast

Breast Neoplasms, Triple Negative Breast Neoplasms

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