Announcements Trials
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Phase

Phase 2 6Phase 1 5Phase 1/2 3Phase 4 2Phase 3 2Phase EARLY_PHASE1 1Phase 2/3 1

Status

Recruiting 3Withdrawn 1Completed 1Active not recruiting 1

Sponsor Class

OTHER 5INDUSTRY 1

Study Type

Interventional 6

Sponsor

Cancer Type

Plasma cell 3Thoracic 1NET 1Gastrointestinal 1Endocrine 1Dermatologic 1CNS 1

Conditions

Smoldering Multiple Myeloma 2Pancreatic Neoplasms 1Neuroendocrine Tumors 1Neoplasms 1Multiple Myeloma 1Multiple Endocrine Neoplasia 1Melanoma 1Lung Neoplasms 1Glioma 1Colorectal Neoplasms 1Central Nervous System Neoplasms 1Brain Neoplasms 1Astrocytoma 1

Interventions

Cisplatin 1514Carboplatin 1416Cyclophosphamide 1359Gemcitabine 1235Bevacizumab 1223Paclitaxel 1210Radiotherapy 1173Docetaxel 1079pembrolizumab 1026Oxaliplatin 934Capecitabine 898Fluorouracil 832Rituximab 729Doxorubicin 683Nivolumab 679Dexamethasone 665Etoposide 660Irinotecan 622Leucovorin 574Pemetrexed 508Drug Therapy 491Cetuximab 481Trastuzumab 467Cytarabine 466Magnetic Resonance Spectroscopy 457Filgrastim 446Prednisone 432Lenalidomide 409Specimen Handling 407Temozolomide 400

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

6 trials
RecentStart dateEnrollment
Phase 2 × Leflunomide × Clear all
NCT04508790 2026-05-04

Leflunomide, Pomalidomide, and Dexamethasone for the Treatment of Relapsed or Refractory Multiple Myeloma

City of Hope Medical Center

Phase 2 Recruiting
29 enrolled
Plasma cell

Multiple Myeloma

NCT05014646 2026-04-30

Leflunomide for the Treatment of High-Risk Smoldering Multiple Myeloma in African-American and European-American Patients

City of Hope Medical Center

Phase 2 Active not recruiting
27 enrolled
Plasma cell

Smoldering Multiple Myeloma

NCT06540937 2024-08-07

Phase II Clinical Study of Leflunomide in the Treatment of MEN-1 Neuroendocrine Tumor

Cancer Institute and Hospital, Chinese Academy of Medical Sciences

Phase 2 Recruiting
50 enrolled
EndocrineNET

Multiple Endocrine Neoplasia, Neuroendocrine Tumors

NCT06229340 2024-01-29

NТО-RAS

N.N. Petrov National Medical Research Center of Oncology

Phase 2 Recruiting
20 enrolled
DermatologicGastrointestinalThoracic

Lung Neoplasms, Melanoma, Neoplasms, Pancreatic Neoplasms, Colorectal Neoplasms

NCT03952832 2019-11-14

Leflunomide in Treating Patients With High-Risk Smoldering Multiple Myeloma

City of Hope Medical Center

Phase 2 Withdrawn
Plasma cell

Smoldering Multiple Myeloma

NCT00003775 2012-09-13

Leflunomide in Treating Patients With Anaplastic Astrocytoma in First Relapse

Pfizer

Phase 2 Completed
60 enrolled
CNS

Astrocytoma, Brain Neoplasms, Glioma, Central Nervous System Neoplasms

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