Announcements Trials
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Phase

Phase 1/2 3Phase 3 1

Status

Recruiting 6Completed 4Active not recruiting 2Withdrawn 1Unknown 1Terminated 1

Sponsor Class

OTHER 4INDUSTRY 4NIH 1

Study Type

Interventional 4

Sponsor

Cancer Type

Plasma cell 1Other hematologic neoplasm 1Breast 1

Conditions

Triple Negative Breast Neoplasms 1Myasthenia Gravis 1Multiple Myeloma 1Hematologic Neoplasms 1Breast Neoplasms 1Breast Diseases 1

Interventions

Cyclophosphamide 956Radiotherapy 847Cisplatin 757Gemcitabine 657Carboplatin 603Docetaxel 598Paclitaxel 585Bevacizumab 580Fluorouracil 504Oxaliplatin 458Rituximab 453Surveys and Questionnaires 449Capecitabine 440Dexamethasone 428Doxorubicin 424Etoposide 411Irinotecan 389Cytarabine 376Filgrastim 369pembrolizumab 330Leucovorin 305Nivolumab 296fludarabine phosphate 294Melphalan 288Magnetic Resonance Spectroscopy 281Peripheral Blood Stem Cell Transplantation 279Blood Specimen Collection 279Methotrexate 276Lenalidomide 276Cetuximab 270

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Completed × OTHER × Leflunomide × Clear all
NCT03709446 2026-03-19

Leflunomide in Previously Treated Metastatic Triple Negative Cancers

Icahn School of Medicine at Mount Sinai

Phase 1/2 Completed
17 enrolled
Breast

Breast Diseases, Breast Neoplasms, Triple Negative Breast Neoplasms

NCT04532372 2024-07-03

Leflunomide for the Treatment of Severe COVID-19 in Patients With a Concurrent Malignancy

City of Hope Medical Center

Phase 1/2 Completed
2 enrolled 7 charts
Other hematologic neoplasm

Hematologic Neoplasms

NCT02509052 2023-10-10

Leflunomide in Treating Patients With Relapsed or Refractory Multiple Myeloma

City of Hope Medical Center

Phase 1/2 Completed
12 enrolled 21 charts
Plasma cell

Multiple Myeloma

NCT01727193 2022-04-14

The Efficacy and Safety of Leflunomide or Azathioprine Therapy in Myasthenia Gravis Patients After Expand Thymectomy

First Affiliated Hospital, Sun Yat-Sen University

Phase 3 Completed
290 enrolled

Myasthenia Gravis

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