Clinical Trials Browser

NCT03625531 2026-04-14

A Trial of Personalized Acupuncture, Fixed Acupuncture, Letrozole and Placebo on Live Birth in Women With PCOS

Phase 3 Completed

1,103 enrolled

Polycystic Ovary Syndrome

NCT00003140 2026-03-27

Letrozole After Tamoxifen in Treating Women With Breast Cancer

Phase 3 Completed

5,187 enrolled

Breast

Breast Neoplasms

NCT00893061 2026-03-17

MNEMOSYNE

Phase 3 Completed

44 enrolled

Breast

Breast Neoplasms

NCT02767661 2026-02-27

MECCA

Phase 3 Completed

263 enrolled

Breast

Breast Neoplasms

NCT07143682 2025-12-16

Letrozole Step up Protocol for Ovulation Induction in Infertile Women With Polycystic Ovary Syndrome

Phase 3 Completed

70 enrolled

Infertility, Polycystic Ovary Syndrome

NCT03079011 2025-11-18

PADA-1

Phase 3 Completed

1,017 enrolled

Breast

Breast Neoplasms

NCT02297438 2025-10-27

A Study Of Palbociclib (PD-0332991) + Letrozole VS. Placebo+ Letrozole For 1st Line Treatment Of Asian Postmenopausal Women With ER+/HER2- Advanced Breast Cancer [PALOMA-4]

Phase 3 Completed

340 enrolled 29 charts

Breast

Breast Neoplasms, Neoplasm Metastasis

NCT03778931 2025-09-15

EMERALD

Phase 3 Completed

478 enrolled 16 charts 2 FDA

Breast

Breast Neoplasms

NCT00601900 2025-05-23

Tamoxifen Citrate or Letrozole With or Without Bevacizumab in Treating Women With Stage IIIB or Stage IV Breast Cancer

Phase 3 Completed

394 enrolled 11 charts

Breast

Breast Neoplasms

NCT00265759 2025-04-23

Exemestane, Letrozole, or Anastrozole in Treating Postmenopausal Women Who Are Undergoing Surgery for Stage II or Stage III Breast Cancer

Phase 3 Completed

622 enrolled 18 charts

Breast

Breast Neoplasms

NCT01958021 2025-03-07

MONALEESA-2

Phase 3 Completed

668 enrolled 15 charts

Breast

Breast Neoplasms

NCT00949598 2025-02-13

Letrozole or Tamoxifen Citrate in Treating Older Postmenopausal Women Undergoing Surgery for Breast Cancer

Phase 3 Completed

177 enrolled

Breast

Breast Neoplasms

NCT01740427 2024-11-14

PALOMA-2

Phase 3 Completed

666 enrolled 22 charts

Breast

Breast Neoplasms, Neoplasm Metastasis

NCT03439046 2024-08-01

BioItaLEE

Phase 3 Completed

287 enrolled

Breast

Breast Neoplasms, Hereditary Sensory and Autonomic Neuropathies

NCT06486870 2024-07-05

Comparison Between Two Ovulation Induction Therapies and LOD on Clinical Outcomes in CC-Resistant PCOS Women

Phase 3 Completed

183 enrolled

Polycystic Ovary Syndrome

NCT00673335 2024-07-01

LIBER

Phase 3 Completed

170 enrolled

BreastGynecologic

Breast Neoplasms, Hereditary Breast and Ovarian Cancer Syndrome

NCT06403488 2024-05-08

Letrozole Dose Increments in PCOS Patients Resistant to Letrozole

Phase 3 Completed

102 enrolled

Polycystic Ovary Syndrome

NCT02278120 2024-03-12

MONALEESA-7

Phase 3 Completed

672 enrolled 16 charts 2 FDA

Breast

Advanced Metastatic Breast Cancer

NCT02941926 2023-10-24

COMPLEEMENT-1

Phase 3 Completed

3,246 enrolled 11 charts

Breast

Breast Neoplasms

NCT00754845 2023-08-25

Letrozole in Breast Cancer Who Have Received 5 Years of Aromatase Inhibitor Therapy

Phase 3 Completed

1,918 enrolled 14 charts

Breast

Breast Neoplasms

NCT00545077 2023-03-31

Bevacizumab + Endocrine Treatment vs Endocrine Treatment as First Line in Postmenopausal Women

Phase 3 Completed

380 enrolled 21 charts

Breast

Breast Neoplasms

NCT00433589 2022-11-17

MINDACT

Phase 3 Completed

6,600 enrolled

Breast

Breast Neoplasms, Carcinoma, Ductal, Breast, Carcinoma, Lobular

NCT02600923 2022-01-20

Palbociclib Plus Letrozole For Postmenopausal Women With HR(+) HER2(-) Advanced Breast Cancer For Whom Letrozole Is Deemed Appropriate

Phase 3 Completed

131 enrolled 12 charts

Breast

Breast Neoplasms

NCT03096847 2021-10-11

Study for Women and Men With Hormone-receptor Positive Locally Advanced or Metastatic Breast Cancer

Phase 3 Completed

502 enrolled 20 charts

Breast

Breast Neoplasms, Osteitis Deformans

NCT02491320 2021-06-23

PCOSAPct

Phase 3 Completed

384 enrolled

Polycystic Ovary Syndrome

NCT00073528 2021-02-24

Study Comparing Lapatinib (GW572016) And Letrozole Versus Letrozole In Subjects With Advanced Or Metastatic Breast Cancer

Phase 3 Completed

1,286 enrolled 41 charts

Breast

Breast Neoplasms

NCT02511639 2020-12-03

MAIN-A

Phase 3 Completed

110 enrolled

Breast

Breast Cancer Metastatic

NCT00553410 2020-03-11

SOLE

Phase 3 Completed

4,884 enrolled 14 charts

Breast

Breast Neoplasms

NCT02995772 2019-06-19

Neoadjuvant Hormonal Therapy Compared to Neoadjuvant Chemotherapy in Stage IIIB/C and IV Breast Cancer Patients

Phase 3 Completed

122 enrolled

Breast

Breast Neoplasms

NCT00719186 2018-06-14

PPCOSII

Phase 3 Completed

750 enrolled 12 charts

Infertility, Polycystic Ovary Syndrome

NCT00004205 2017-12-12

BIG 1-98

Phase 3 Completed

8,028 enrolled

Breast

Breast Carcinoma In Situ, Breast Neoplasms, Carcinoma, Ductal, Breast

NCT02980965 2017-11-13

Neoadjuvant Chemo-endocrine Therapy Versus Chemotherapy Alone in ER-positive, HER2-negative Breast Cancer

Phase 3 Completed

249 enrolled

Breast

Breast Neoplasms

NCT00171704 2017-03-03

A Study to Evaluate the Effect of Letrozole and Tamoxifen on Bone and Lipids in Postmenopausal Women With Breast Cancer

Phase 3 Completed

263 enrolled 12 charts

Breast

Breast Neoplasms

NCT00329940 2017-02-24

Safety and Rheumatologic Tolerability of Letrozole in Postmenopausal Patients With Hormone Receptor Positive Breast Cancer

Phase 3 Completed

200 enrolled

Breast

Breast Neoplasms

NCT00332852 2017-02-23

Letrozole as Early Adjuvant Treatment of Postmenopausal Patients With Primary Breast Cancer

Phase 3 Completed

655 enrolled

Breast

Breast Neoplasms

NCT00330317 2017-02-07

Safety and Efficacy of Hormone Therapy With Letrozole in Postmenopausal Women With Breast Cancer

Phase 3 Completed

300 enrolled

Breast

Breast Neoplasms

NCT00107263 2016-12-06

Zoledronate in Preventing Bone Loss in Postmenopausal Women Who Are Receiving Letrozole for Stage I, Stage II, or Stage IIIA Breast Cancer

Phase 3 Completed

558 enrolled

Breast

Breast Neoplasms, Osteoporosis

NCT00248170 2016-04-19

FACE

Phase 3 Completed

4,172 enrolled 7 charts

Breast

Breast Neoplasms

NCT00044291 2015-07-31

Phase III Study of Atamestane Plus Toremifene Versus Letrozole in Advanced Breast Cancer

Phase 3 Completed

865 enrolled

Breast

Breast Neoplasms, Neoplasms, Hormone-Dependent, Carcinoma, Ductal, Breast, Carcinoma, Lobular

NCT00050011 2014-03-21

Zoledronic Acid - Letrozole Adjuvant Synergy Trial (ZFAST) - Cancer Treatment Related Bone Loss in Postmenopausal Women With Estrogen Receptor Positive and/or Progesterone Receptor Positive Breast Cancer Receiving Adjuvant Hormonal Therapy

Phase 3 Completed

602 enrolled 13 charts

Breast

Bone Diseases, Metabolic, Breast Neoplasms, Osteoporosis

NCT00963729 2013-08-12

Chemotherapy or Letrozole Before Surgery in Treating Postmenopausal Women With Breast Cancer That Can Be Removed By Surgery

Phase 3 Completed

756 enrolled

Breast

Breast Neoplasms

NCT01577017 2012-06-14

The Effects of Letrozole And Clomiphene Citrate For Induction of Ovulation In Polycystic Ovarian Syndrome(PCOS)

Phase 3 Completed

150 enrolled

Polycystic Ovary Syndrome

NCT00171340 2012-04-16

Zoledronic Acid in the Prevention of Cancer Treatment Related Bone Loss in Postmenopausal Women Receiving Letrozole for Breast Cancer.

Phase 3 Completed

1,065 enrolled 10 charts

Breast

Bone Diseases, Metabolic, Breast Neoplasms

NCT00171314 2012-04-11

The Use of Zoledronic Acid to Prevent Cancer-treatment Bone Loss in Post-menopausal Women Receiving Adjuvant Letrozole for Breast Cancer

Phase 3 Completed

527 enrolled 11 charts

Breast

Breast Neoplasms

NCT00332709 2011-11-16

Safety/Efficacy of Letrozole Monotherapy or in Combination With Zoledronic Acid as Extended Adjuvant Treatment of Postmenopausal Patients With Primary Breast Cancer

Phase 3 Completed

83 enrolled 14 charts

Breast

Breast Neoplasms, Osteoporosis