Clinical Trials

Breast Neoplasms, Pain, Postoperative

NCT07475520 2026-03-16

Lidocaine IV Injection With Different Doses for Patients With Neuropathic Pain After Mastectomy

Phase 2 Active not recruiting

Neuralgia

NCT04716699 2026-03-10

Systemic and Local Levels of Lidocaine During Surgery for the Removal of Glioblastoma

Phase 1 Completed

12 enrolled

CNS

Glioblastoma

NCT05044468 2026-03-09

EXPAREL or Lidocane as Local Anesthetic in Patients Undergoing Pleuroscopy With Pleural Biopsy and Indwelling Pleural Catheter Placement

80 enrolled

Malignant Pleural Neoplasm

NCT07432399 2026-03-06

PILDI

Phase 2 Recruiting

Phase EARLY_PHASE1 Not yet recruiting

Colonic Neoplasms, Colorectal Neoplasms

NCT07425678 2026-02-23

Comparison of Systemic Opioid (Morphine) and Pre-Incision Bilateral Scalp Nerve Block for Pain Management in Craniotomy Patients

Phase 4 Completed

62 enrolled

Supratentorial Neoplasms

NCT07408193 2026-02-20

The Role of Coadministration of Lidocaine and Ketamine in Opioid-Refractory Chronic Cancer-Related Pain.

24 enrolled

Cancer Pain, Opioid-Related Disorders, Neoplasms

NCT06661902 2026-02-17

BURN

Phase 1/2 Completed

350 enrolled

Prostatic Neoplasms

NCT07408414 2026-02-13

The Effect of Local Anesthesia Techniques on Postoperative Pain After Laser Treatment of Pilonidal Sinus

Phase NA Recruiting

Pilonidal Sinus

NCT06923787 2026-02-05

PILDI

Phase 2 Recruiting

Colonic Neoplasms

NCT05153785 2026-01-15

Perioperative Intravenous Lidocaine in Liver Surgery

Phase 2/3 Completed

124 enrolled

Liver Neoplasms, Pain, Postoperative

NCT04874038 2025-11-17

Prevention of Persistent Pain With LidocAine iNfusions in Breast Cancer Surgery (PLAN)

Phase 3 Recruiting

1,602 enrolled

Phase 1/2 Active not recruiting

Breast Neoplasms, Pain, Postoperative, Chronic Pain

NCT07034950 2025-09-11

Effective Dose and Safety of Esketamine During Ultrasound-guided Hepatic Tumor Thermal Ablation

79 enrolled

Liver Neoplasms, Pain

NCT06057675 2025-08-19

Tranexamic Acid in Nasal Mohs Reconstruction

Phase 2 Recruiting

Phase NA Not yet recruiting

Postoperative Hemorrhage

NCT07108959 2025-08-07

ESPB

40 enrolled

Breast Neoplasms

NCT05017246 2025-07-31

Comparing Intrathecal Morphine and Intraoperative Lidocaine Infusion to Epidural Anesthesia With Postoperative PCA for Patients Undergoing Exploratory Laparotomy

Phase 2 Terminated

110 enrolled 18 charts

Leiomyoma, Ileus

NCT05294640 2025-07-08

Bacteriostatic Saline as a Local Anesthetic in Minor Eyelid Procedures

Phase 4 Completed

95 enrolled 9 charts

Eyelid Neoplasms, Hordeolum

NCT06404983 2025-07-03

Opioid-free Anaesthesia in Breast Cancer Surgery

Phase NA Recruiting

200 enrolled

Breast Neoplasms, Pain, Postoperative, Chronic Pain

NCT00540982 2025-07-02

Vinorelbine in Treating Patients With Advanced Solid Tumors That Have Not Responded to Treatment and Liver Dysfunction

Phase 1/2 Completed

47 enrolled 7 charts

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT06747390 2025-04-29

856397

Phase 1 Recruiting

Head & Neck

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Oropharyngeal Neoplasms

NCT05742438 2025-04-02

Effects of Dexmedetomidine/Lidocaine/Intrathecal Morphine on Cancer Metastasis Biomarker After Colorectal Surgery

114 enrolled

Phase EARLY_PHASE1 Recruiting

Inflammation, Neoplasm Metastasis, Colorectal Neoplasms

NCT04048278 2025-03-03

Lidocaine Infusion in Pancreatic Cancer

46 enrolled

Pancreatic Neoplasms

NCT05920980 2025-02-19

Effect of Lidocaine on Postoperative Pain in Elderlypatients Undergoing Colorectal Cancer Surgery

276 enrolled

Colorectal Neoplasms

NCT04176419 2024-11-12

Perioperative Analgesia on Postoperative Opioid Usage and Pain Control in H&N Cancer Surgery

Phase 3 Terminated

Phase NA Active not recruiting

Head & Neck

Head and Neck Neoplasms

NCT02647385 2024-10-08

Pain Control in Breast Surgery: Analgesia, Opioid Consumption and Inflammatory Response Evaluation

50 enrolled

Agnosia, Breast Neoplasms, Neoplasms

NCT06631625 2024-10-08

Effect of Addition of Dexmedetomidine or Ketamine to Intravenous Infusion of Lidocaine on Proinflammatory Cytokines in Pelvi-abdominal Cancer Surgeries.

Phase 1 Completed

45 enrolled

Gynecologic

Pelvic Neoplasms

NCT06405776 2024-05-08

Effect of Lidocaine on Postoperative Pain and Long-term Survival in Elderly Patients Undergoing Colorectal Surgery

Phase NA Recruiting

276 enrolled

Colorectal Neoplasms

NCT06301308 2024-04-24

A Novel Application of 2% Lidocaine Injection for Male Rigid cycstoscopy-a Patient-blinded Randomised Trial

Phase 3 Withdrawn

Urinary Bladder Neoplasms

NCT05412576 2024-03-13

a Pilot Study of Lidocaine Infusion for Postoperative Analgesia in Elderly Patients With Colorectal Cancer Surgery

220 enrolled

Colorectal Neoplasms

NCT04250805 2024-01-31

GASTROXY

Phase 2 Terminated

17 enrolled

Feeding and Eating Disorders, Neoplasms, Pain

NCT06201039 2024-01-11

CLAWED

80 enrolled

Head & Neck

Head and Neck Neoplasms

NCT03824808 2023-10-25

Effect of Perioperative Intravenous Lidocaine Infusion in Robotic-Assisted Urologic Surgery

Phase 4 Terminated

21 enrolled 12 charts

Kidney Neoplasms, Prostatic Neoplasms

NCT06064331 2023-10-03

Effect of Intravenous Lignocaine Infusion on Intraoperative End Tidal Desflurane Concentration Requirements

48 enrolled

Gynecologic

Appendicitis, Cholelithiasis, Ovarian Cysts

NCT05957653 2023-07-24

Lidocaine Combined With Sufentanil for Preventing Catheter-related Bladder Discomfort

Phase 4 Unknown

140 enrolled

Prostatic Neoplasms

NCT05250791 2023-06-09

FLICOR

50 enrolled

Recurrence, Colorectal Neoplasms

NCT05850702 2023-05-09

Attenuation of the Hemodynamic Response to Double-lumen Endotracheal Intubation With Nebulized Lidocaine

Phase 4 Unknown

92 enrolled

Lung Neoplasms

NCT04703803 2023-04-25

Efficacy of Myofascial Pain Syndrome Treatment in Patients With Cancer in Palliative Care

Phase 3 Completed

LymphoidOther hematologic neoplasm

Cancer Pain, Myofascial Pain Syndromes, Neoplasms

NCT04003012 2023-03-09

Pain Control in Pediatric Oncology: Utility of EMLA Cream vs Lidocaine Injection in Lumbar Punctures

Phase 4 Completed

10 enrolled 5 charts

Leukemia-Lymphoma

NCT04840511 2023-01-13

The Effect of Perioperative Lidocaine Infusion on Neutrophil Extracellular Trapping

Phase NA Active not recruiting

60 enrolled

Urologic Neoplasms

NCT04868747 2023-01-12

The Effect of Perioperative Lidocaine Infusion on Neutrophil Extracellular Trapping

Phase NA Withdrawn

Stomach Neoplasms

NCT05672394 2023-01-05

US-Guided Serratus Anterior Plane Block Versus Thoracic Epidural in Patients Undergoing Thoracotomy

74 enrolled

Lung Neoplasms, Chronic Pain, Acute Pain

NCT03801031 2022-12-06

Sexual Dysfunction in Gynecologic Oncology Patients

Phase 4 Terminated

4 enrolled 7 charts

Other

Sexual Dysfunction, Physiological

NCT05560035 2022-09-29

The Effect of Intravenous Lidocaine on THBS2 and Angiogenic Factors Expression in Women Undergoing Cervical Cancer Surgery

60 enrolled

Gynecologic

Uterine Cervical Neoplasms, Neoplasm Metastasis, Disease Progression

NCT04295330 2022-08-26

Efficacy of Intravenous Lidocaine on Postoperative Pain and Recovery in Patients Undergoing Hepatectomy

260 enrolled

Carcinoma, Hepatocellular

NCT04732455 2022-07-11

TIPN

60 enrolled

Breast Neoplasms, Peripheral Nervous System Diseases

NCT03821545 2022-05-20

The Anti-inflammatory Effect of Anesthetics in Abdominal Surgery

82 enrolled

Colorectal Neoplasms

NCT05369650 2022-05-11

To Explore the Safety and Efficacy of Intravenous Infusion of Different Doses of Lidocaine in Patients

120 enrolled

Liver Neoplasms

NCT01204242 2022-03-24

IRB-HSR# 13957: IV Lidocaine for Patients Undergoing Primary Breast Cancer Surgery:

Phase 2 Completed

78 enrolled

Breast Neoplasms

NCT02924480 2022-03-09

Lidocaine

50 enrolled