Clinical Trials

Head & Neck

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Oropharyngeal Neoplasms

NCT06404983 2026-05-06

Opioid-free Anaesthesia in Breast Cancer Surgery

Phase NA Recruiting

200 enrolled

Breast Neoplasms, Pain, Postoperative, Chronic Pain

NCT03699995 2026-04-08

MoleMapper, Visiomed, and Confocal Microscopy in Screening Participants for Melanoma

Phase NA Terminated

17 enrolled

Dermatologic

Melanoma, Nevus, Pigmented

NCT05072314 2026-03-25

LOLIPOP

Phase 3 Recruiting

4,300 enrolled

Breast Neoplasms, Pain, Postoperative

NCT07475520 2026-03-16

Lidocaine IV Injection With Different Doses for Patients With Neuropathic Pain After Mastectomy

Phase 2 Active not recruiting

Neuralgia

NCT04716699 2026-03-10

Systemic and Local Levels of Lidocaine During Surgery for the Removal of Glioblastoma

Phase 1 Completed

12 enrolled

CNS

Glioblastoma

NCT05044468 2026-03-09

EXPAREL or Lidocane as Local Anesthetic in Patients Undergoing Pleuroscopy With Pleural Biopsy and Indwelling Pleural Catheter Placement

80 enrolled

Malignant Pleural Neoplasm

NCT07432399 2026-03-06

PILDI

Phase 2 Recruiting

Phase EARLY_PHASE1 Not yet recruiting

Colonic Neoplasms, Colorectal Neoplasms

NCT07425678 2026-02-23

Comparison of Systemic Opioid (Morphine) and Pre-Incision Bilateral Scalp Nerve Block for Pain Management in Craniotomy Patients

Phase 4 Completed

62 enrolled

Supratentorial Neoplasms

NCT07408193 2026-02-20

The Role of Coadministration of Lidocaine and Ketamine in Opioid-Refractory Chronic Cancer-Related Pain.

24 enrolled

Cancer Pain, Opioid-Related Disorders, Neoplasms

NCT06661902 2026-02-17

BURN

Phase 1/2 Completed

350 enrolled

Prostatic Neoplasms

NCT07408414 2026-02-13

The Effect of Local Anesthesia Techniques on Postoperative Pain After Laser Treatment of Pilonidal Sinus

Phase NA Recruiting

Pilonidal Sinus

NCT06923787 2026-02-05

PILDI

Phase 2 Recruiting

Phase NA Not yet recruiting

Colonic Neoplasms

NCT07347977 2026-01-16

LidCRM

1,400 enrolled

Carcinoma, Non-Small-Cell Lung, Recurrence

NCT05153785 2026-01-15

Perioperative Intravenous Lidocaine in Liver Surgery

Phase 2/3 Completed

124 enrolled

Liver Neoplasms, Pain, Postoperative

NCT04874038 2025-11-17

Prevention of Persistent Pain With LidocAine iNfusions in Breast Cancer Surgery (PLAN)

Phase 3 Recruiting

1,602 enrolled

Phase 1/2 Active not recruiting

Breast Neoplasms, Pain, Postoperative, Chronic Pain

NCT07034950 2025-09-11

Effective Dose and Safety of Esketamine During Ultrasound-guided Hepatic Tumor Thermal Ablation

79 enrolled

Liver Neoplasms, Pain

NCT06057675 2025-08-19

Tranexamic Acid in Nasal Mohs Reconstruction

Phase 2 Recruiting

Phase NA Not yet recruiting

Postoperative Hemorrhage

NCT07108959 2025-08-07

ESPB

40 enrolled

Breast Neoplasms

NCT05017246 2025-07-31

Comparing Intrathecal Morphine and Intraoperative Lidocaine Infusion to Epidural Anesthesia With Postoperative PCA for Patients Undergoing Exploratory Laparotomy

Phase 2 Terminated

110 enrolled 18 charts

Leiomyoma, Ileus

NCT05294640 2025-07-08

Bacteriostatic Saline as a Local Anesthetic in Minor Eyelid Procedures

Phase 4 Completed

95 enrolled 9 charts

Eyelid Neoplasms, Hordeolum

NCT00540982 2025-07-02

Vinorelbine in Treating Patients With Advanced Solid Tumors That Have Not Responded to Treatment and Liver Dysfunction

Phase 1/2 Completed

47 enrolled 7 charts

Phase 3 Active not recruiting

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT01916317 2025-04-09

Randomized Controlled Trial to Assess Blockade of Voltage Gated Sodium Channels During Surgery in Operable Breast Cancer

1,600 enrolled

Operable Breast Cancer

NCT05742438 2025-04-02

Effects of Dexmedetomidine/Lidocaine/Intrathecal Morphine on Cancer Metastasis Biomarker After Colorectal Surgery

114 enrolled

Phase EARLY_PHASE1 Recruiting

Inflammation, Neoplasm Metastasis, Colorectal Neoplasms

NCT04048278 2025-03-03

Lidocaine Infusion in Pancreatic Cancer

46 enrolled

Pancreatic Neoplasms

NCT05920980 2025-02-19

Effect of Lidocaine on Postoperative Pain in Elderlypatients Undergoing Colorectal Cancer Surgery

276 enrolled

Colorectal Neoplasms

NCT04176419 2024-11-12

Perioperative Analgesia on Postoperative Opioid Usage and Pain Control in H&N Cancer Surgery

Phase 3 Terminated

Phase NA Active not recruiting

Head & Neck

Head and Neck Neoplasms

NCT02647385 2024-10-08

Pain Control in Breast Surgery: Analgesia, Opioid Consumption and Inflammatory Response Evaluation

50 enrolled

Agnosia, Breast Neoplasms, Neoplasms

NCT06631625 2024-10-08

Effect of Addition of Dexmedetomidine or Ketamine to Intravenous Infusion of Lidocaine on Proinflammatory Cytokines in Pelvi-abdominal Cancer Surgeries.

Phase 1 Completed

45 enrolled

Gynecologic

Pelvic Neoplasms

NCT06405776 2024-05-08

Effect of Lidocaine on Postoperative Pain and Long-term Survival in Elderly Patients Undergoing Colorectal Surgery

Phase NA Recruiting

276 enrolled

Colorectal Neoplasms

NCT06301308 2024-04-24

A Novel Application of 2% Lidocaine Injection for Male Rigid cycstoscopy-a Patient-blinded Randomised Trial

Phase 3 Withdrawn

Urinary Bladder Neoplasms

NCT05412576 2024-03-13

a Pilot Study of Lidocaine Infusion for Postoperative Analgesia in Elderly Patients With Colorectal Cancer Surgery

220 enrolled

Colorectal Neoplasms

NCT04250805 2024-01-31

GASTROXY

Phase 2 Terminated

17 enrolled

Feeding and Eating Disorders, Neoplasms, Pain

NCT06201039 2024-01-11

CLAWED

Phase NA Unknown

80 enrolled

Head & Neck

Head and Neck Neoplasms

NCT03824808 2023-10-25

Effect of Perioperative Intravenous Lidocaine Infusion in Robotic-Assisted Urologic Surgery

Phase 4 Terminated

21 enrolled 12 charts

Kidney Neoplasms, Prostatic Neoplasms

NCT06064331 2023-10-03

Effect of Intravenous Lignocaine Infusion on Intraoperative End Tidal Desflurane Concentration Requirements

48 enrolled

Gynecologic

Appendicitis, Cholelithiasis, Ovarian Cysts

NCT05800834 2023-09-28

MorphineGEL

Phase 2 Unknown

106 enrolled

BreastHead & Neck

Cancer Pain, Breast Neoplasms, Head and Neck Neoplasms, Wounds and Injuries

NCT05957653 2023-07-24

Lidocaine Combined With Sufentanil for Preventing Catheter-related Bladder Discomfort

Phase 4 Unknown

140 enrolled

Prostatic Neoplasms

NCT05250791 2023-06-09

FLICOR

Phase NA Unknown

50 enrolled

Recurrence, Colorectal Neoplasms

NCT05850702 2023-05-09

Attenuation of the Hemodynamic Response to Double-lumen Endotracheal Intubation With Nebulized Lidocaine

Phase 4 Unknown

92 enrolled

Lung Neoplasms

NCT04703803 2023-04-25

Efficacy of Myofascial Pain Syndrome Treatment in Patients With Cancer in Palliative Care

Phase 3 Completed

LymphoidOther hematologic neoplasm

Cancer Pain, Myofascial Pain Syndromes, Neoplasms

NCT04003012 2023-03-09

Pain Control in Pediatric Oncology: Utility of EMLA Cream vs Lidocaine Injection in Lumbar Punctures

Phase 4 Completed

10 enrolled 5 charts

Leukemia-Lymphoma

NCT04840511 2023-01-13

The Effect of Perioperative Lidocaine Infusion on Neutrophil Extracellular Trapping

Phase NA Active not recruiting

60 enrolled

Urologic Neoplasms

NCT04868747 2023-01-12

The Effect of Perioperative Lidocaine Infusion on Neutrophil Extracellular Trapping

Phase NA Withdrawn

Stomach Neoplasms

NCT05672394 2023-01-05

US-Guided Serratus Anterior Plane Block Versus Thoracic Epidural in Patients Undergoing Thoracotomy

74 enrolled

Lung Neoplasms, Chronic Pain, Acute Pain

NCT03801031 2022-12-06

Sexual Dysfunction in Gynecologic Oncology Patients

Phase 4 Terminated

4 enrolled 7 charts

Other

Sexual Dysfunction, Physiological

NCT05560035 2022-09-29

The Effect of Intravenous Lidocaine on THBS2 and Angiogenic Factors Expression in Women Undergoing Cervical Cancer Surgery

Phase NA Unknown

60 enrolled

Gynecologic

Uterine Cervical Neoplasms, Neoplasm Metastasis, Disease Progression

NCT04295330 2022-08-26

Efficacy of Intravenous Lidocaine on Postoperative Pain and Recovery in Patients Undergoing Hepatectomy

260 enrolled

Carcinoma, Hepatocellular

NCT04732455 2022-07-11

TIPN

60 enrolled