Clinical Trials

153 enrolled

Burkitt Lymphoma, Leukemia, Biphenotypic, Acute

NCT04216524 2026-04-14

Venetoclax, SL-401, and Chemotherapy for the Treatment of Blastic Plasmacytoid Dendritic Cell Neoplasm

40 enrolled

Myeloid

Blastic Plasmacytoid Dendritic Cell Neoplasm

NCT06124157 2026-04-14

A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

222 enrolled

Phase 2 Active not recruiting

Burkitt Lymphoma

NCT02143414 2026-04-13

Blinatumomab and Combination Chemotherapy or Dasatinib, Prednisone, and Blinatumomab in Treating Older Patients With Acute Lymphoblastic Leukemia

53 enrolled 12 charts

Phase 2 Active not recruiting

Burkitt Lymphoma, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT05303792 2026-04-07

Testing the Combination of Inotuzumab Ozogamicin and Lower Dose Chemotherapy Compared to Usual Chemotherapy for Adults With B-Cell Acute Lymphoblastic Leukemia or B-Cell Lymphoblastic Lymphoma

68 enrolled

Burkitt Lymphoma, Precursor B-Cell Lymphoblastic Leukemia-Lymphoma

NCT06918431 2026-03-17

Asparaginase Erwinia Chrysanthemi With Chemotherapy for the Treatment of High-Risk Adults With Newly Diagnosed Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma

53 enrolled

Burkitt Lymphoma, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT02723994 2026-03-11

A Phase 2 Study of Ruxolitinib With Chemotherapy in Children With Acute Lymphoblastic Leukemia

171 enrolled

Burkitt Lymphoma, Leukemia

NCT06390319 2026-02-27

Adding Dasatinib Or Venetoclax To Improve Responses In Children With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia (ALL) Or Lymphoma (T-LLY) Or Mixed Phenotype Acute Leukemia (MPAL)

100 enrolled

Leukemia, Biphenotypic, Acute, Lymphoma, T-Cell, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

NCT06533748 2026-02-12

Therapy for Newly Diagnosed Patients With B-Cell Precursor Acute Lymphoblastic Leukemia and Lymphoma

128 enrolled

Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT02523976 2026-02-11

Dasatinib Combined With Chemotherapy in Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia

30 enrolled

Leukemia, Philadelphia Chromosome, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00501826 2026-01-07

Combination Chemotherapy and Nelarabine in Treating Patients With T-cell Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma

160 enrolled

Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

NCT06387121 2025-12-17

Efficacy and Safety of Low-dose Chemotherapy Plus Immuno-targeted Drugs in Newly Diagnosed Adult Ph- B-ALL

53 enrolled

Phase 2 Not yet recruiting

Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT07227584 2025-11-12

ALL Backbone in AYAs

67 enrolled

Leukemia, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT02877303 2025-11-06

Blinatumomab, Inotuzumab Ozogamicin, and Combination Chemotherapy as Frontline Therapy in Treating Patients With B Acute Lymphoblastic Leukemia

80 enrolled

Burkitt Lymphoma, Precursor B-Cell Lymphoblastic Leukemia-Lymphoma

NCT00136435 2025-10-20

A Study in Adults With Untreated Acute Lymphoblastic Leukemia

100 enrolled 17 charts

Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT05645718 2025-10-07

Study of Pedi-cRIB: Mini-Hyper-CVD With Condensed Rituximab, Inotuzumab Ozogamicin and Blinatumomab (cRIB) for Relapsed Therapy for Pediatric With B-Cell Lineage Acute Lymphocytic Leukemia

27 enrolled

Phase 2 Active not recruiting

Leukemia

NCT01920737 2025-09-16

A Novel "Pediatric-Inspired" Regimen With Reduced Myelosuppressive Drugs for Adults (Aged 18-60) With Newly Diagnosed Ph Negative Acute Lymphoblastic Leukemia

39 enrolled

Leukemia

NCT04546399 2025-09-10

A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL)

461 enrolled

Burkitt Lymphoma, Down Syndrome

NCT04440267 2025-08-06

Efficacy of Acute Lymphoblastic Leukemia-Based Therapy in Treating Patients With Acute Leukemia of Ambiguous Lineage

50 enrolled

Leukemia, Biphenotypic, Acute

NCT05660473 2025-08-01

Pediatric-inspired Regimen Combined With Venetoclax for Adolescent and Adult Patients With de Novo Philadelphia Chromosome-Negative Acute Lymphoblastic Leukemia

100 enrolled

Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT02420717 2025-06-08

Ruxolitinib Phosphate or Dasatinib With Chemotherapy in Treating Patients With Relapsed or Refractory Philadelphia Chromosome-Like Acute Lymphoblastic Leukemia

11 enrolled 13 charts

Burkitt Lymphoma

NCT03384654 2025-05-25

A Study to Evaluate the Efficacy and Safety of Daratumumab in Pediatric and Young Adult Participants Greater Than or Equal to (>=)1 and Less Than or Equal to (<=) 30 Years of Age With Relapsed/Refractory Precursor B-cell or T-cell Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma

47 enrolled 22 charts

Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT02828358 2025-02-27

Azacitidine and Combination Chemotherapy in Treating Infants With Acute Lymphoblastic Leukemia and KMT2A Gene Rearrangement

78 enrolled 15 charts

Burkitt Lymphoma, Leukemia, Biphenotypic, Acute

NCT03488225 2024-07-16

Combination Chemotherapy and Inotuzumab Ozogamicin in Treating Patients With B Acute Lymphoblastic Leukemia

4 enrolled 11 charts

Burkitt Lymphoma

NCT06210750 2024-05-17

Adding Targeted Drugs to Usual Chemotherapy for Adults With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia (T-ALL) and T-Cell Lymphoblastic Lymphoma (T-LBL)

Phase 2 Withdrawn

Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

NCT02396043 2023-06-18

Modified BFM-95 Regimen as First-Line Chemotherapy in Adults With T- Lymphoblastic Lymphoma

Phase 2 Unknown

50 enrolled

Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT01256398 2023-04-04

Dasatinib Followed by Stem Cell Transplant in Treating Older Patients With Newly Diagnosed Acute Lymphoblastic Leukemia

66 enrolled 12 charts

Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00551460 2023-01-10

S0535, Gemtuzumab and Combination Chemotherapy in Treating Patients With Previously Untreated Acute Promyelocytic Leukemia

78 enrolled 8 charts

Leukemia, Leukemia, Promyelocytic, Acute

NCT03518112 2022-11-04

Low-Intensity Chemotherapy and Blinatumomab in Treating Patients With Philadelphia Chromosome Negative Relapsed or Refractory Acute Lymphoblastic Leukemia

6 enrolled 10 charts

Burkitt Lymphoma

NCT01700946 2022-09-28

Therapy for Pediatric Relapsed or Refractory Precursor B-Cell Acute Lymphoblastic Leukemia and Lymphoma

80 enrolled 13 charts

Leukemia, Lymphoma

NCT03286634 2022-09-28

ASIA Down Syndrome Acute Lymphoblastic Leukemia 2016

60 enrolled

Down Syndrome, Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT01451515 2022-06-28

NHL16: Study For Newly Diagnosed Patients With Acute Lymphoblastic Lymphoma

23 enrolled 14 charts

Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT02067143 2021-09-08

LAL1913

204 enrolled

Tumor-Agnostic

Neoplasm Metastasis, Neoplasm, Residual

NCT00558519 2021-08-18

Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Acute Lymphoblastic Leukemia

Phase 2 Unknown

318 enrolled 9 charts

Leukemia

NCT00866749 2019-09-10

Augmented Berlin-Frankfurt-Munster (BFM) Therapy for Adolescent/Young Adults With Acute Lymphoblastic Leukemia or Acute Lymphoblastic Lymphoma

120 enrolled 11 charts

Leukemia, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT01432145 2019-07-09

6MP

74 enrolled 13 charts

BreastGynecologic

Breast Neoplasms, Ovarian Neoplasms

NCT02518750 2019-04-03

Re-Induction Therapy for Relapsed Pediatric T-Cell Acute Lymphoblastic Leukemia or Lymphoma

3 enrolled 6 charts

Lymphoma, Non-Hodgkin, Leukemia, B-Cell, Leukemia, T-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00458848 2019-02-15

LAL0904

470 enrolled 10 charts

Leukemia, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT02419469 2018-06-11

Augmented Berlin-Frankfurt-Munster Therapy Plus Ofatumumab for Young Adults With Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma

1 enrolled 4 charts

Leukemia, Lymphoma, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT02419755 2018-03-07

Bortezomib and Vorinostat in Younger Patients With Refractory or Relapsed MLL Rearranged Hematologic Malignancies

12 enrolled 10 charts

Leukemia, Biphenotypic, Acute, Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00186875 2017-07-28

Therapy for Pediatric Relapsed or Refractory Acute Lymphoblastic Leukemia

47 enrolled 10 charts

Leukemia, Lymphoma, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT02660762 2017-06-19

Modified MRCUKALLⅫ/ECOGE2993 Regimen for ALL

Phase 2 Unknown

100 enrolled

Leukemia

NCT00973752 2017-03-30

Treatment of Older Adults With Acute Lymphoblastic Leukemia

30 enrolled 9 charts

Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00548431 2017-01-09

NOPHO ALL-2008 Pilot Study on Consolidation Therapy for Children and Adolescents With Acute Lymphoblastic Leukemia

38 enrolled 8 charts

Leukemia, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00003700 2016-07-06

Combination Chemotherapy in Treating Patients With Untreated Acute Lymphoblastic Leukemia

163 enrolled

Leukemia, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00262925 2015-05-05

Combination Chemotherapy and Alemtuzumab in Treating Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia

12 enrolled 6 charts

Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00004688 2015-03-25

Phase II Study of Carmustine, Streptozocin, and Mercaptopurine for Refractory or Recurrent Brain Neoplasms

35 enrolled

CNS

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Genetic Diseases, Inborn, Rare Diseases

NCT00109837 2015-03-25

S0333 Combination Chemotherapy in Treating Patients With Newly Diagnosed Acute Lymphoblastic Leukemia

79 enrolled 6 charts

Leukemia, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00002665 2015-03-06

SWOG-9400 Combination Chemotherapy With or Without Bone Marrow Transplantation in Treating Patients With Previously Untreated Acute Lymphocytic Leukemia

Classical hematologyLymphoidOther hematologic neoplasm

50 enrolled

Leukemia, Neutropenia, Thrombocytopenia, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00003783 2014-07-28

Combination Chemotherapy in Treating Children With Very High Risk Acute Lymphocytic Leukemia

36 enrolled