Clinical Trials
33 trialsNCT07603505 2026-06-04
NAE-PCOS
Jinnah Sindh Medical University
Phase 1 Active not recruiting
NCT07459595 2026-03-10
Metformin Versus Myo-inositol in the Management of Polycystic Ovarian Disease: A Comparative Study
Combined Military Hospital Gujranwala
Phase 1 Not yet recruiting
NCT02336087 2026-02-04
Gemcitabine Hydrochloride, Paclitaxel Albumin-Stabilized Nanoparticle Formulation, Metformin Hydrochloride, and a Standardized Dietary Supplement in Treating Patients With Pancreatic Cancer That Cannot be Removed by Surgery
City of Hope Medical Center
Phase 1 Active not recruiting
NCT06044025 2026-01-15
A Feasibility Study Evaluating a Role for Maintenance Therapy in Patients With Biochemically Progressive Castration Sensitive Prostate Cancer on Intermittent Androgen Deprivation Therapy
University of Arkansas
Phase 1 Recruiting
NCT07098299 2025-11-06
Metformin Combined With Chemotherapy and/or Immunotherapy in Solid Malignancies
Barbara Ann Karmanos Cancer Institute
Phase 1 Recruiting
NCT03889795 2025-10-20
Phase IB Metformin, Digoxin, Simvastatin in Solid Tumors
University of Toledo
Phase 1 Active not recruiting
NCT05536037 2025-05-15
Metformin for the Prevention of Oral Cancer in Patients With Oral Premalignant Lesions
Thomas Jefferson University
Phase 1 Terminated
NCT01430351 2025-05-07
Temozolomide, Memantine Hydrochloride, Mefloquine, and Metformin Hydrochloride in Treating Patients With Glioblastoma Multiforme After Radiation Therapy
M.D. Anderson Cancer Center
Phase 1 Terminated
NCT03311308 2025-05-06
A Trial of Pembrolizumab and Metformin Versus Pembrolizumab Alone in Advanced Melanoma
University of Pittsburgh
Phase 1 Recruiting
NCT02339168 2025-05-01
Enzalutamide and Metformin Hydrochloride in Treating Patients With Hormone-Resistant Prostate Cancer
University of California, Davis
Phase 1 Completed
NCT01529593 2025-03-24
Temsirolimus in Combination With Metformin in Patients With Advanced Cancers
M.D. Anderson Cancer Center
Phase 1 Terminated
NCT04116203 2025-02-28
PCOS
University of Alberta
Phase 1 Completed
NCT03829020 2024-08-22
Metformin, Nelfinavir, and Bortezomib in Treating Patients With Relapsed and/or Refractory Multiple Myeloma
Mayo Clinic
Phase 1 Completed
NCT02312661 2024-05-06
OVMET
University Medical Center Groningen
Phase 1 Completed
NCT03017833 2023-10-04
Sapanisertib and Metformin in Treating Patients With Advanced or Metastatic Relapsed or Refractory Cancers
M.D. Anderson Cancer Center
Phase 1 Completed
NCT01528046 2023-01-13
Metformin in Children With Relapsed or Refractory Solid Tumors
H. Lee Moffitt Cancer Center and Research Institute
Phase 1 Completed
NCT02278965 2022-08-17
Metformin and Omega-3 Fatty Acids in Woman With a History of Early Stage Breast Cancer
Columbia University
Phase 1 Completed
NCT02048384 2021-04-12
A Study of Metformin With or Without Rapamycin as Maintenance Therapy After Induction Chemotherapy in Subjects With Pancreatic Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Phase 1 Completed
NCT02948283 2021-02-12
Metformin Hydrochloride and Ritonavir in Treating Patients With Relapsed or Refractory Multiple Myeloma or Chronic Lymphocytic Leukemia
City of Hope Medical Center
Phase 1 Completed
NCT02244567 2021-02-02
U-C OC IN PCOS
Beni-Suef University
Phase 1 Unknown
NCT02325401 2020-06-11
Dose-finding Study of Metformin With Chemoradiation in Locally Advanced Head and Neck Squamous Cell Carcinoma
University of Cincinnati
Phase 1 Completed
NCT02050009 2019-02-20
Metformin Hydrochloride, Carboplatin, and Paclitaxel in Treating Patients With Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
Fox Chase Cancer Center
Phase 1 Withdrawn
NCT01849276 2019-01-31
Metformin+Cytarabine for the Treatment of Relapsed/Refractory AML
Northwestern University
Phase 1 Terminated
NCT03465345 2018-08-03
Study of Metformin Plus Oligomeric Procyanidin Complex for Pharmacologic Manipulation of AGE (Advanced Glycation Endproducts) Levels in Prostate Cancer Patients
Medical University of South Carolina
Phase 1 Withdrawn
NCT02086526 2018-03-19
Targeting Pathways in Polycystic Ovary Syndrome (PCOS) Using Metformin (MET)
Mayo Clinic
Phase 1 Completed
NCT01650506 2017-08-30
Study of Erlotinib and Metformin in Triple Negative Breast Cancer
Columbia University
Phase 1 Completed
NCT01324180 2017-08-07
Vincristine, Dexamethasone, Doxorubicin, and PEG-asparaginase (VPLD) and Metformin for Relapsed Childhood Acute Lymphoblastic Leukemia (ALL)
H. Lee Moffitt Cancer Center and Research Institute
Phase 1 Completed
NCT01442870 2017-05-09
Evaluation of Clinical Safety of Combining Metformin With Anticancer Chemotherapy
Tufts Medical Center
Phase 1 Completed
NCT00933309 2016-02-19
The Impact of Obesity and Obesity Treatments on Breast Cancer
M.D. Anderson Cancer Center
Phase 1 Completed
NCT01816659 2015-11-18
An Open-Labeled Pilot Study of Biomarker Response Following Short-Term Exposure to Metformin
M.D. Anderson Cancer Center
Phase 1 Terminated
NCT01087983 2015-11-11
Lapatinib With Sirolimus or Metformin
M.D. Anderson Cancer Center
Phase 1 Completed
NCT01954732 2015-07-15
Metformin Hydrochloride in Treating Patients With Pancreatic Cancer That Can be Removed by Surgery
Case Comprehensive Cancer Center
Phase 1 Withdrawn
NCT01440127 2015-03-26
Impact of Pretreatment With Metformin on Colorectal Cancer Stem Cells (CCSC) and Related Pharmacodynamic Markers
Tufts Medical Center
Phase 1 Terminated