Clinical Trials Browser

Phase 2 × Recruiting × Metformin × Clear all

NCT07226453 2026-05-07

PNOC041

Phase 2 Recruiting

Posterior Fossa Ependymal Tumor

NCT04114136 2026-04-24

Anti-PD-1 mAb Plus Metabolic Modulator in Solid Tumor Malignancies

Phase 2 Recruiting

DermatologicGastrointestinalHead & Neck

Adenocarcinoma Of Esophagus, Squamous Cell Carcinoma of Head and Neck, Carcinoma, Hepatocellular, Melanoma

NCT07291297 2026-03-05

Metformin Hydrochloride in Combination With Standard of Care Systemic Therapy in Previously Untreated Advanced Unresectable or Metastatic Soft Tissue Sarcoma

Phase 2 Recruiting

Sarcoma

NCT07387900 2026-02-06

Evaluation of the Chemo-preventive Effect of Combined Topical and Systemic Metformin on Oral Leukoplakia

Phase 2 Recruiting

Leukoplakia, Oral

NCT04945148 2025-11-21

OPTIMUM

Phase 2 Recruiting

Glioblastoma

NCT07182526 2025-09-19

Effects of Adding Quercetin or Alpha Lipoic Acid to Usual Care on Symptoms and Blood Markers in Iraqi Women With Polycystic Ovary Syndrome

Phase 2 Recruiting

Polycystic Ovary Syndrome

NCT06377696 2025-09-02

Remote Cognitive Assessment and Wearable Device While Assessing the Impact of Metformin in Patients With History of Cranial Radiation Therapy

Phase 2 Recruiting

Brain Neoplasms

NCT05929495 2025-07-25

Phase 2, Open-label, Single-arm Study on the Use of Metformin as Adjunctive Therapy in High-grade Glioma

Phase 2 Recruiting

Glioblastoma, Glioma, Neoplasms

NCT06687876 2025-07-10

MEMENTO

Phase 2 Recruiting

Gastrointestinal

Adenocarcinoma Of Esophagus, Adenocarcinoma, Esophageal Neoplasms

NCT03675893 2025-06-15

RESOLVE: Abemaciclib + Letrozole +/- Metformin, Zotatifin, or Gedatolisib in Endometrial or Low-Grade Serous Ovarian Cancer

Phase 2 Recruiting

Ovarian Neoplasms, Endometrial Neoplasms

NCT06826092 2025-02-13

Metformin for the Treatment of mCRC Patients Undergoing FOLFIRI Plus Target Therapy

Phase 2 Recruiting

Progression-Free Survival

NCT04741945 2024-11-22

Repurposing Metformin As a Leukemia-preventive Drug in CCUS and LR-MDS

Phase 2 Recruiting

Classical hematologyOther hematologic neoplasm

Cytopenia, Anemia, Refractory, with Excess of Blasts, Preleukemia

NCT02647827 2024-10-09

PIAII

Phase 2 Recruiting

Insulin Resistance, Polycystic Ovary Syndrome, Hyperandrogenism

NCT06537843 2024-08-05

VenCM

Phase 2 Recruiting

Other hematologic neoplasm

Leukemia, Myeloid, Acute

NCT03379909 2023-09-21

TROJAN

Phase 2 Recruiting

Non-Muscle Invasive Bladder Neoplasms, Urinary Bladder Neoplasms

NCT04758000 2023-08-04

Metform-Bone

Phase 2 Recruiting

Sarcoma, Ewing, Osteosarcoma