Clinical Trials
356 trialsNCT02755844 2026-05-27
ENDOLA
Hospices Civils de Lyon
Phase 1/2 Completed
NCT07603505 2026-05-27
NAE-PCOS
Jinnah Sindh Medical University
Phase 1 Recruiting
NCT02186847 2026-05-22
Chemotherapy and Radiation Therapy With or Without Metformin Hydrochloride in Treating Patients With Stage III Non-small Cell Lung Cancer
NRG Oncology
Phase 2 Completed
NCT07604779 2026-05-22
Enhancing PCOS Management for Better Outcomes of Intracytoplasmic Sperm Injection
Beni-Suef University
Phase NA Active not recruiting
NCT07604870 2026-05-22
Krill Oil and Metformin in Women With PCOS and Metabolically Unhealthy Obesity
Firat University
Phase 2 Completed
NCT07585396 2026-05-18
Inositol in Letrozol Resistant PCOS Women
Kafrelsheikh University
Phase 2/3 Completed
NCT05036226 2026-05-13
COAST
Medical University of South Carolina
Phase 1/2 Recruiting
NCT04414540 2026-05-08
Combining Pembrolizumab and Metformin in Metastatic Head and Neck Cancer Patients
University of Cincinnati
Phase 2 Active not recruiting
NCT07226453 2026-05-07
PNOC041
University of California, San Francisco
Phase 2 Recruiting
NCT06882291 2026-05-04
Intermittent Fasting Diet Versus Resistive Exercise Program on Insulin Resistance in Obese Women With P.C.O.S
Cairo University
Phase NA Completed
NCT05230758 2026-05-01
Met Med Can
The Hospital for Sick Children
Phase 3 Recruiting
NCT04742751 2026-04-30
An Open-Label Pilot Intervention Trial to Prevent Diabetes in Prediabetic Adult Survivors of Childhood Cancer
St. Jude Children's Research Hospital
Phase 2 Active not recruiting
NCT01905046 2026-04-28
Metformin Hydrochloride in Preventing Breast Cancer in Patients With Atypical Hyperplasia or In Situ Breast Cancer
Alliance for Clinical Trials in Oncology
Phase 3 Active not recruiting
NCT04114136 2026-04-24
Anti-PD-1 mAb Plus Metabolic Modulator in Solid Tumor Malignancies
University of Pittsburgh
Phase 2 Recruiting
NCT02874430 2026-04-22
Metformin Hydrochloride and Doxycycline in Treating Patients With Localized Breast or Uterine Cancer
Thomas Jefferson University
Phase 2 Terminated
NCT05237960 2026-04-20
Metformin for the Prevention of Oral Cancer in Patients With Oral Leukoplakia or Erythroplakia
University of Arizona
Phase 2 Active not recruiting
NCT05966792 2026-04-13
SGLT2 Inhibitors in Treating Patients With PCOS
Shanghai 10th People's Hospital
Phase NA Completed
NCT05445791 2026-04-09
METLUNG
Instituto Nacional de Cancerologia de Mexico
Phase 3 Recruiting
NCT02437656 2026-03-31
METCAP
Centre Oscar Lambret
Phase 2 Completed
NCT02122185 2026-03-27
Metformin and Chemotherapy in Treating Patients With Stage III-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
University of Chicago
Phase 2 Completed
NCT07459595 2026-03-10
Metformin Versus Myo-inositol in the Management of Polycystic Ovarian Disease: A Comparative Study
Combined Military Hospital Gujranwala
Phase 1 Not yet recruiting
NCT05965908 2026-03-06
Effect of Liraglutide in Obese Women With Polycystic Ovary Syndrome
Beni-Suef University
Phase 3 Completed
NCT02946996 2026-03-05
Study of Pharmacologic Manipulation of AGE (Advanced Glycation Endproducts) Levels in Prostate Cancer Patients Receiving Androgen Deprivation Therapy
Medical University of South Carolina
Phase 2 Terminated
NCT07291297 2026-03-05
Metformin Hydrochloride in Combination With Standard of Care Systemic Therapy in Previously Untreated Advanced Unresectable or Metastatic Soft Tissue Sarcoma
Wake Forest University Health Sciences
Phase 2 Recruiting
NCT03905941 2026-02-23
SHK002
University of Virginia
Phase EARLY_PHASE1 Withdrawn
NCT04850846 2026-02-09
Investigation of Metformin for the Prevention of Progression of Precursor Multiple Myeloma
Dana-Farber Cancer Institute
Phase 2 Active not recruiting
NCT05767515 2026-02-09
PCOS
Khyber Medical University Peshawar
Phase NA Completed
NCT07387900 2026-02-06
Evaluation of the Chemo-preventive Effect of Combined Topical and Systemic Metformin on Oral Leukoplakia
Cairo University
Phase 2 Recruiting
NCT02336087 2026-02-04
Gemcitabine Hydrochloride, Paclitaxel Albumin-Stabilized Nanoparticle Formulation, Metformin Hydrochloride, and a Standardized Dietary Supplement in Treating Patients With Pancreatic Cancer That Cannot be Removed by Surgery
City of Hope Medical Center
Phase 1 Active not recruiting
NCT07387679 2026-02-04
Myo-inositol Versus Metformin in Patients With Polycystic Ovarian Syndrome to Treat Obesity
RESnTEC, Institute of Research
Phase NA Completed
NCT07380841 2026-02-02
PCOS-COMBO (9)
Islamabad Medical and Dental College
Phase NA Completed
NCT06763328 2026-01-22
Metformin for the Treatment of Insulin Resistance in Women With Stage I-III Breast Cancer Completing Chemotherapy
City of Hope Medical Center
Phase 3 Recruiting
NCT04576104 2026-01-21
Megestrol Acetate Compared With Megestrol Acetate and Metformin to Prevent Endometrial Cancer
Northwestern University
Phase 2 Active not recruiting
NCT06044025 2026-01-15
A Feasibility Study Evaluating a Role for Maintenance Therapy in Patients With Biochemically Progressive Castration Sensitive Prostate Cancer on Intermittent Androgen Deprivation Therapy
University of Arkansas
Phase 1 Recruiting
NCT05023967 2026-01-05
Metformin and Nightly Fasting in Women With Early Breast Cancer
M.D. Anderson Cancer Center
Phase 2 Active not recruiting
NCT04691960 2025-12-19
A Pilot Study of Ketogenic Diet and Metformin in Glioblastoma: Feasibility and Metabolic Imaging
Weill Medical College of Cornell University
Phase 2 Active not recruiting
NCT05183204 2025-12-18
Paxalisib With a High Fat, Low Carb Diet and Metformin for Glioblastoma
Weill Medical College of Cornell University
Phase 2 Suspended
NCT03109847 2025-12-11
Metformin to Mitigate Sequelae of Radioactive Iodine Treatment for Thyroid Cancers
Thomas Jefferson University
Phase 2 Terminated
NCT04536805 2025-12-08
REPAIR
Institut Cancerologie de l'Ouest
Phase 1/2 Recruiting
NCT05515978 2025-12-04
PragMet
University of Colorado, Denver
Phase EARLY_PHASE1 Recruiting
NCT05802212 2025-11-25
Effect of Metformin on Patients With Polycystic Ovary Syndrome
Peking University Third Hospital
Phase NA Completed
NCT04945148 2025-11-21
OPTIMUM
Hopital Foch
Phase 2 Recruiting
NCT01797523 2025-11-06
A Phase II, Single-Arm Study of RAD001 (Everolimus), Letrozole, and Metformin in Patients With Advanced or Recurrent Endometrial Carcinoma
M.D. Anderson Cancer Center
Phase 2 Active not recruiting
NCT07098299 2025-11-06
Metformin Combined With Chemotherapy and/or Immunotherapy in Solid Malignancies
Barbara Ann Karmanos Cancer Institute
Phase 1 Recruiting
NCT03889795 2025-10-20
Phase IB Metformin, Digoxin, Simvastatin in Solid Tumors
University of Toledo
Phase 1 Active not recruiting
NCT04931017 2025-10-07
Metformin for Chemoprevention of Lung Cancer in Overweight or Obese Individuals at High Risk for Lung Cancer
Northwestern University
Phase 2 Active not recruiting
NCT06479434 2025-10-07
Serum Biomarker Levels Improvement in Poly Cystic Ovarian Syndrome: Impact of Metformin Compared to Healthy Controls
Aga Khan University
Phase NA Completed
NCT05680805 2025-09-19
Metabolic Responses of Metformin and Genetic Polymorphisms of SLC22A1 Gene in PCOS
Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Phase 4 Active not recruiting
NCT07182526 2025-09-19
Effects of Adding Quercetin or Alpha Lipoic Acid to Usual Care on Symptoms and Blood Markers in Iraqi Women With Polycystic Ovary Syndrome
Al-Mustansiriyah University
Phase 2 Recruiting
NCT01750567 2025-09-09
A Pilot Study of Metformin Therapy in Patients With Relapsed Chronic Lymphocytic Leukemia (CLL) and Untreated CLL
University of Michigan Rogel Cancer Center
Phase 2 Completed