Clinical Trials Browser

Congenital Abnormalities, Blast Crisis, Leukemia, Erythroblastic, Acute, Leukemia, Megakaryoblastic, Acute, Leukemia, Monocytic, Acute, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Acute

NCT01523639 2018-12-19

G-LUCAS

Phase 2 Terminated

8 enrolled

Gastrointestinal

Fatty Liver, Colorectal Neoplasms

NCT01578551 2018-12-19

Study of Metformin Plus Paclitaxel/Carboplatin/Bevacizumab in Patients With Adenocarcinoma.

Phase 2 Terminated

25 enrolled 9 charts

Thoracic

Adenocarcinoma of Lung, Carcinoma, Non-Small-Cell Lung

NCT01926769 2018-05-15

A Phase II Study to Determine the Safety and Efficacy of Second-line Treatment With Metformin and Chemotherapy (FOLFOX6 or FOFIRI) in the Second Line Threatment of Advanced Colorectal Cancer

Phase 2 Terminated

2 enrolled

Gastrointestinal

Colorectal Neoplasms

NCT02019979 2018-05-04

METRO

Phase 2 Terminated

14 enrolled 7 charts

Thoracic

Lung Neoplasms

NCT02473094 2017-11-28

NEOMETRE

Phase 2 Terminated

3 enrolled

Gastrointestinal

Adenocarcinoma, Carcinoma, Rectal Neoplasms

NCT02815397 2017-11-17

DLBCL

Phase 2 Terminated

2 enrolled 3 charts

Lymphoid

Lymphoma, Large B-Cell, Diffuse

NCT02360059 2017-08-17

Metformin for Reduction of Paclitaxel-Related Neuropathy in Patients With Breast Cancer

Phase 2 Terminated

1 enrolled 3 charts

Breast

Breast Neoplasms

NCT01215032 2017-05-15

Metformin in Castration-Resistant Prostate Cancer

Phase 2 Terminated

21 enrolled 8 charts

Genitourinary

Prostatic Neoplasms

NCT02402348 2017-02-08

Pilot Study of Metformin in HNSCC to Investigate the Effects of MF, Tumor Genotype and MF-genotype Interactions, on Tumor Metabolism and Anoikis

Phase EARLY_PHASE1 Terminated

3 enrolled

Head & Neck

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT02319200 2017-01-11

METFOVIR

Phase 3 Terminated

11 enrolled

Gastrointestinal

Death, Fibrosis, Carcinoma, Hepatocellular, Hepatitis C, Chronic

NCT01997775 2016-09-30

Metformin in Stage IV Lung Adenocarcinoma

Phase 2 Terminated

13 enrolled

Thoracic

Adenocarcinoma of Lung, Carcinoma, Non-Small-Cell Lung

NCT01632020 2016-07-11

Effect of Metformin on Biomarkers of Colorectal Tumor Cell Growth

Phase 2 Terminated

7 enrolled 6 charts

Gastrointestinal

Colorectal Neoplasms

NCT01816659 2015-11-18

An Open-Labeled Pilot Study of Biomarker Response Following Short-Term Exposure to Metformin

Phase 1 Terminated

3 enrolled

Gastrointestinal

Colorectal Neoplasms

NCT01167738 2015-04-24

PACT-17

Phase 2 Terminated

60 enrolled

Gastrointestinal

Pancreatic Neoplasms

NCT01440127 2015-03-26

Impact of Pretreatment With Metformin on Colorectal Cancer Stem Cells (CCSC) and Related Pharmacodynamic Markers

Phase 1 Terminated

9 enrolled

Gastrointestinal

Colonic Neoplasms

NCT01486043 2015-01-30

Metformin and Transient Hyperglycemia

Phase NA Terminated

4 enrolled 9 charts

LymphoidOther hematologic neoplasm

Diabetes Mellitus, Hyperglycemia, Insulin Resistance, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00682890 2014-08-20

Combination Metformin and Oral Contraception for Polycystic Ovary Syndrome (PCOS)

Phase 4 Terminated

28 enrolled 7 charts

Insulin Resistance, Polycystic Ovary Syndrome

NCT01477060 2014-02-20

Modulation of Response to Hormonal Therapy With Lapatinib and/or Metformin in Patients With Metastatic Breast Cancer

Phase 2 Terminated

32 enrolled

Breast

Breast Neoplasms

NCT00881725 2012-06-19

ANIMATE

Phase 2 Terminated

24 enrolled

Genitourinary

Prostatic Neoplasms