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Phase

Phase 2 207Phase 3 117Phase 1 37Phase 1/2 25Phase NA 23Phase 4 17Phase 2/3 6Phase EARLY_PHASE1 4

Status

Completed 4Withdrawn 1Recruiting 1Enrolling by invitation 1

Sponsor Class

OTHER 4

Study Type

Interventional 4

Sponsor

Cancer Type

Lymphoid 2CNS 2Other hematologic neoplasm 1

Conditions

Rhabdoid Tumor 2Medulloblastoma 2Ependymoma 2Brain Neoplasms 2Recurrence 1Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 1Precursor Cell Lymphoblastic Leukemia-Lymphoma 1Lymphoma, Mantle-Cell 1Lymphoma, Large B-Cell, Diffuse 1Burkitt Lymphoma 1

Interventions

Magnetic Resonance Spectroscopy 23Metformin 14pembrolizumab 12Radiotherapy 12Biopsy 11Nivolumab 9Fluorouracil 9Cyclophosphamide 9Temozolomide 7Radiation 7Bevacizumab 7gallium 68 PSMA-11 6Sirolimus 6Rituximab 6Letrozole 6Etoposide 6Cisplatin 6Aspirin 6olaparib 5Surveys and Questionnaires 5Radiosurgery 5Oxaliplatin 5Irinotecan 5Indocyanine Green 5Granulocyte Colony-Stimulating Factor 5Fluorodeoxyglucose F18 5Dexamethasone 5aldesleukin 4Surgical Procedures, Operative 4Proflavine 4

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Phase EARLY_PHASE1 × Completed × Methotrexate × Clear all
NCT01760226 2025-10-14

DA-EPOCH-R

Baylor College of Medicine

Phase EARLY_PHASE1 Completed
4 enrolled
Lymphoid

Lymphoma, Large B-Cell, Diffuse

NCT01184885 2025-05-04

A Pilot Study to Determine the Safety and Tolerability of Sirolimus Given With Hyper-CVAD Chemotherapy

Thomas Jefferson University

Phase EARLY_PHASE1 Completed
7 enrolled 8 charts
LymphoidOther hematologic neoplasm

Burkitt Lymphoma, Recurrence, Lymphoma, Mantle-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

NCT02905110 2025-03-25

Methotrexate and Etoposide Infusions Into the Fourth Ventricle in Children with Recurrent Posterior Fossa Brain Tumors

The University of Texas Health Science Center, Houston

Phase EARLY_PHASE1 Completed
3 enrolled
CNS

Brain Neoplasms, Ependymoma, Medulloblastoma, Rhabdoid Tumor

NCT01737671 2018-01-19

Methotrexate Infusion Into the Fourth Ventricle in Children With Malignant Fourth Ventricular Brain Tumors: A Pilot Study

M.D. Anderson Cancer Center

Phase EARLY_PHASE1 Completed
7 enrolled
CNS

Brain Neoplasms, Ependymoma, Medulloblastoma, Rhabdoid Tumor

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