Clinical Trials

CNSGastrointestinalGenitourinaryGynecologicSarcoma

Familial ependymoma, Ovarian Germ Cell Cancer, Astrocytoma, Kidney Neoplasms, Liver Neoplasms, Medulloblastoma, Wilms Tumor, Neuroblastoma, Oligodendroglioma, Ovarian Neoplasms, Sarcoma, Osteosarcoma, Teratoma, Testicular Neoplasms, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral, Optic Nerve Glioma

NCT00005081 2014-08-21

Carmustine Plus O6-benzylguanine in Treating Patients With Recurrent or Progressive Glioma

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Central Nervous System Neoplasms, Gliosarcoma

NCT00612989 2014-07-16

Ph I 5-day Temozolomide + O6-BG in Treatment of Pts w Recurrent / Progressive GBM

42 enrolled

Brain Neoplasms, Glioblastoma, Glioma, Gliosarcoma

NCT00362921 2014-07-10

Gliadel Wafer and O6-Benzylguanine in Treating Patients With Recurrent Glioblastoma Multiforme

52 enrolled

Brain Neoplasms, Glioblastoma, Gliosarcoma

NCT00613093 2014-07-09

Ph. II Temozolomide + O6-BG in Treatment of Pts w Temozolomide-Resistant Malignant Glioma

67 enrolled

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Central Nervous System Neoplasms

NCT00003766 2014-03-06

O6-benzylguanine Followed by Surgery in Treating Patients With Solid Tumors That Can Be Removed During Surgery

25 enrolled

Other solid neoplasm

Unspecified Adult Solid Tumor, Protocol Specific

NCT00253487 2014-01-06

Combination Chemotherapy and Radiation Therapy in Treating Younger Patients Who Are Undergoing an Autologous Stem Cell Transplant for Newly Diagnosed Gliomas

Phase NA Completed

Astrocytoma, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00052780 2013-09-30

Temozolomide and O6-Benzylguanine in Treating Children With Recurrent Brain Tumors

72 enrolled

Familial ependymoma, Astrocytoma, Medulloblastoma, Oligodendroglioma, Choroid Plexus Neoplasms, Optic Nerve Glioma

NCT00005066 2013-09-05

O6-benzylguanine and Carmustine in Treating Patients With Recurrent, Metastatic, or Locally Advanced Soft Tissue Sarcoma

12 enrolled

Sarcoma

NCT00006474 2013-06-20

Temozolomide and O6-benzylguanine in Treating Patients With Newly Diagnosed, Recurrent, or Progressive Anaplastic Glioma

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

NCT00612638 2013-06-19

Ph. I Temozolomide + O6-BG + Irinotecan in Treatment of Pts w Recurrent / Progressive Cerebral Anaplastic Gliomas

96 enrolled

Glioblastoma, Glioma, Gliosarcoma

NCT00046878 2013-03-28

Carmustine and O(6)-Benzylguanine in Treating Patients With Newly Diagnosed Supratentorial Glioblastoma Multiforme

Phase 2 Withdrawn

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00003348 2013-02-20

Carmustine Plus O(6)-Benzylguanine in Treating Patients With Recurrent or Progressive Gliomas of the Brain

56 enrolled

Astrocytoma, Brain Neoplasms, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00005961 2013-02-11

O6-benzylguanine and Carmustine in Treating Patients With Unresectable Locally Recurrent or Metastatic Melanoma

40 enrolled

Dermatologic

Melanoma

NCT00003765 2013-02-05

O6-benzylguanine and Carmustine in Treating Children With Refractory CNS Tumors

36 enrolled

Familial ependymoma, Astrocytoma, Medulloblastoma, Oligodendroglioma, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Optic Nerve Glioma

NCT00017147 2013-01-30

S0001 RT and Carmustine With or Without O6BG in Patients With New Glioblastoma Multiforme or Gliosarcoma

Phase 3 Completed

183 enrolled

Glioblastoma, Gliosarcoma

NCT00086970 2013-01-24

Ifosfamide With or Without O(6)-Benzylguanine in Treating Patients With Unresectable, Metastatic Solid Tumors

32 enrolled

Other solid neoplasm

Unspecified Adult Solid Tumor, Protocol Specific

NCT00003613 2013-01-11

O6-benzylguanine and Carmustine in Treating Patients With Stage IA-IIA Cutaneous T-cell Lymphoma

20 enrolled

DermatologicLymphoid

Lymphoma, T-Cell, Cutaneous

NCT00389090 2012-02-09

A Phase II Study of Temozolomide and O6-Benzylguanine (O6-BG) in Patients With Temozolomide-Resistant Anaplastic Glioma

Phase 2 Terminated

32 enrolled

Astrocytoma, Glioma, Oligodendroglioma

NCT00002604 2010-07-08

O(6)-Benzylguanine and Carmustine in Treating Patients With Solid Tumors

28 enrolled

Other solid neoplasm

Unspecified Adult Solid Tumor, Protocol Specific

NCT00003567 2010-06-11

Gene Therapy and Chemotherapy in Treating Patients With Advanced Solid Tumors or Non-Hodgkin's Lymphoma

CNSLymphoidOther hematologic neoplasmSarcoma

8 enrolled

Astrocytoma, Brain Neoplasms, Burkitt Lymphoma, Ependymoma, Glioblastoma, Glioma, Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Oligodendroglioma, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Glioma, Subependymal, Gliosarcoma, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00004072 2010-06-11

O6-benzylguanine And Carmustine in Treating Patients With Multiple Myeloma

17 enrolled

Plasma cell

Multiple Myeloma, Neoplasms, Plasma Cell

NCT00005981 2010-06-10

Combination Chemotherapy in Treating Patients With Metastatic Colorectal Cancer

13 enrolled

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00045721 2009-10-16

Carmustine Implants and O(6)-Benzylguanine in Treating Children With Recurrent Malignant Glioma

3 enrolled

Astrocytoma, Central Nervous System Neoplasms

NCT00004892 2009-02-09

O6-Benzylguanine and Carmustine Implants in Treating Patients With Recurrent Malignant Glioma