Announcements Trials
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Phase

Phase 1 2Phase 2 1Phase 1/2 1

Status

Withdrawn 1Unknown 1No longer available 1Completed 1Active not recruiting 1

Sponsor Class

INDUSTRY 5OTHER 1

Study Type

Interventional 4Expanded_access 1

Sponsor

Cancer Type

CNS 5

Conditions

Glioma 4Oligodendroglioma 2Glioblastoma 2Astrocytoma 2Diffuse Intrinsic Pontine Glioma 1

Interventions

pembrolizumab 1033Carboplatin 971Paclitaxel 942Gemcitabine 799Cisplatin 757Docetaxel 698Bevacizumab 637Nivolumab 520Pemetrexed 507Capecitabine 475Cyclophosphamide 473Fluorouracil 425Dexamethasone 410Rituximab 391Oxaliplatin 352Injections 347Trastuzumab 314atezolizumab 312Cetuximab 291Leucovorin 290Irinotecan 271130-nm albumin-bound paclitaxel 257Prednisone 251Ipilimumab 244Doxorubicin 241Lenalidomide 231Fulvestrant 226fludarabine 219durvalumab 211Erlotinib Hydrochloride 196

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
INDUSTRY × OKN 007 × Clear all
NCT04388475 2025-08-12

Open-label Study Investigating of OKN-007 Combined With Temozolomide in Patients With Recurrent Glioblastoma

Oblato, Inc.

Phase 2 Completed
57 enrolled
CNS

Glioma

NCT05561374 2024-11-29

Study of Safety and Pharmacokinetic Properties of Oral OKN-007 in Patients with Recurrent High-Grade Glioma

Oblato, Inc.

Phase 1 Active not recruiting
16 enrolled
CNS

Astrocytoma, Glioblastoma, Glioma, Oligodendroglioma

NCT05518838 2024-11-08

Expanded Access to OKN-007 for Patients With Diffuse Midline Glioma, H3 K27-altered

Oblato, Inc.

No longer available
CNS

Diffuse Intrinsic Pontine Glioma

NCT01672463 2023-03-29

OKN-007

Oblato, Inc.

Phase 1 Unknown
31 enrolled
CNS

Glioma

NCT03649464 2022-10-07

Investigation of Oral OKN-007 in Recurrent High-grade Glioma Participants

Oblato, Inc.

Phase 1/2 Withdrawn
CNS

Astrocytoma, Glioblastoma, Glioma, Oligodendroglioma

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