Announcements Trials
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Phase

Phase 1 3Phase 2 1Phase 1/2 1

Status

Active not recruiting 2Withdrawn 1Unknown 1Completed 1

Sponsor Class

INDUSTRY 4OTHER 1

Study Type

Interventional 5Expanded_access 1

Sponsor

Cancer Type

CNS 5

Conditions

Glioma 4Glioblastoma 3Oligodendroglioma 2Astrocytoma 2

Interventions

Cyclophosphamide 3155Cisplatin 3151Carboplatin 2929Paclitaxel 2671Radiotherapy 2643Gemcitabine 2544pembrolizumab 2324Docetaxel 2154Bevacizumab 2126Fluorouracil 1819Capecitabine 1780Oxaliplatin 1709Dexamethasone 1589Nivolumab 1516Doxorubicin 1477Rituximab 1453Etoposide 1341Magnetic Resonance Spectroscopy 1261Irinotecan 1232Leucovorin 1212Cytarabine 1123Pemetrexed 1060Drug Therapy 1060fludarabine 1044Vincristine 956Specimen Handling 928Prednisone 924Cetuximab 919Lenalidomide 916Trastuzumab 897

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Interventional × OKN 007 × Clear all
NCT03587038 2025-12-10

OKN-007 in Combination With Adjuvant Temozolomide Chemoradiotherapy for Newly Diagnosed Glioblastoma

University of Oklahoma

Phase 1 Active not recruiting
27 enrolled
CNS

Glioblastoma

NCT04388475 2025-08-12

Open-label Study Investigating of OKN-007 Combined With Temozolomide in Patients With Recurrent Glioblastoma

Oblato, Inc.

Phase 2 Completed
57 enrolled
CNS

Glioma

NCT05561374 2024-11-29

Study of Safety and Pharmacokinetic Properties of Oral OKN-007 in Patients with Recurrent High-Grade Glioma

Oblato, Inc.

Phase 1 Active not recruiting
16 enrolled
CNS

Astrocytoma, Glioblastoma, Glioma, Oligodendroglioma

NCT01672463 2023-03-29

OKN-007

Oblato, Inc.

Phase 1 Unknown
31 enrolled
CNS

Glioma

NCT03649464 2022-10-07

Investigation of Oral OKN-007 in Recurrent High-grade Glioma Participants

Oblato, Inc.

Phase 1/2 Withdrawn
CNS

Astrocytoma, Glioblastoma, Glioma, Oligodendroglioma

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