Announcements Trials
Browse Landscape

Phase

Phase 2 2Phase 1/2 2

Status

Completed 2Terminated 1Active not recruiting 1

Sponsor Class

INDUSTRY 17OTHER 4NIH 1

Study Type

Interventional 4

Sponsor

Cancer Type

Thoracic 1Other hematologic neoplasm 1Myeloid 1Dermatologic 1Classical hematology 1

Conditions

Splenomegaly 1Primary Myelofibrosis 1Neoplasm Metastasis 1Melanoma 1Leukemia 1Epidermolysis Bullosa Dystrophica 1Carcinoma, Squamous Cell 1Carcinoma, Non-Small-Cell Lung 1Anemia 1Adenocarcinoma 1

Interventions

Cyclophosphamide 2067Radiotherapy 1990Cisplatin 1856Carboplatin 1560Gemcitabine 1454Paclitaxel 1320Bevacizumab 1320pembrolizumab 1237Docetaxel 1227Oxaliplatin 1184Capecitabine 1176Fluorouracil 1083Dexamethasone 979Magnetic Resonance Spectroscopy 971Nivolumab 936Rituximab 929Drug Therapy 915Surveys and Questionnaires 898Doxorubicin 845Etoposide 843Radiosurgery 816Blood Specimen Collection 816Irinotecan 784Cytarabine 743fludarabine 726Leucovorin 684Surgical Procedures, Operative 639Lenalidomide 618Biopsy 594fludarabine phosphate 569

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
OTHER × ON 01910 × Clear all
NCT05764395 2026-04-27

Rigosertib Plus Pembrolizumab in Treating Patients With Unresectable/Metastatic Melanoma Refractory to PD-1 Inhibitors

Vanderbilt-Ingram Cancer Center

Phase 2 Active not recruiting
7 enrolled
Dermatologic

Melanoma

NCT03786237 2026-02-24

Rigosertib for RDEB-SCC

Salzburger Landeskliniken

Phase 1/2 Completed
2 enrolled

Carcinoma, Squamous Cell, Epidermolysis Bullosa Dystrophica

NCT04263090 2024-05-09

Rigosertib Plus Nivolumab for KRAS+ NSCLC Patients Who Progressed on First-Line Treatment

Icahn School of Medicine at Mount Sinai

Phase 1/2 Completed
25 enrolled
Thoracic

Adenocarcinoma, Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis

NCT02730884 2020-08-07

Single-Arm Study of the Efficacy and Safety of Oral Rigosertib in Patients With Myelofibrosis (MF) and Anemia

M.D. Anderson Cancer Center

Phase 2 Terminated
3 enrolled 6 charts
Classical hematologyMyeloidOther hematologic neoplasm

Anemia, Leukemia, Splenomegaly, Primary Myelofibrosis

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