Clinical Trials Browser

Phase 3 × Interventional × Observation × Clear all

NCT04267848 2026-05-27

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

Phase 3 Recruiting

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT06498635 2026-05-27

Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial

Phase 3 Recruiting

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT02954874 2026-05-15

Testing MK-3475 (Pembrolizumab) as Adjuvant Therapy for Triple Receptor-Negative Breast Cancer

Phase 3 Active not recruiting

Breast Carcinoma In Situ, Breast Neoplasms, Triple Negative Breast Neoplasms

NCT02595944 2026-05-13

ANVIL

Phase 3 Active not recruiting

Carcinoma, Non-Small-Cell Lung

NCT03233711 2026-05-13

Nivolumab After Combined Modality Therapy in Treating Patients With High Risk Stage II-IIIB Anal Cancer

Phase 3 Active not recruiting

Gastrointestinal

Anal Canal Carcinoma, Anus Neoplasms

NCT03244384 2026-05-13

AMBASSADOR

Phase 3 Active not recruiting

Ureteral Neoplasms

NCT03811015 2026-05-13

Testing Immunotherapy Versus Observation in Patients With HPV Throat Cancer

Phase 3 Active not recruiting

Oropharyngeal Neoplasms

NCT07388524 2026-05-13

Testing the Impact of an Anti-Cancer Drug, Atezolizumab, After Surgery to Prevent Early Stage Non-small Cell Lung Cancer From Returning, AASI-NSCLC Trial

Phase 3 Not yet recruiting

Carcinoma, Non-Small-Cell Lung

NCT05812807 2026-05-08

Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab

Phase 3 Recruiting

Anatomic Stage I Breast Cancer AJCC v8

NCT03180268 2026-05-07

Observation or Radiation Therapy in Treating Patients With Newly Diagnosed Grade II Meningioma That Has Been Completely Removed by Surgery

Phase 3 Recruiting

Meningioma

NCT02176967 2026-05-05

Response and Biology-Based Risk Factor-Guided Therapy in Treating Younger Patients With Non-high Risk Neuroblastoma

Phase 3 Active not recruiting

Neuroblastoma, Ganglioneuroblastoma

NCT06401330 2026-05-05

A Study Using Risk Factors to Determine Treatment for Children With Favorable Histology Wilms Tumors (FHWT)

Phase 3 Recruiting

Stage I Mixed Cell Type Kidney Wilms Tumor

NCT06647953 2026-05-05

Testing a Standardized Approach to Surgery and Chemotherapy for Type I Pleuropulmonary Blastoma or the Addition of an Anti-cancer Drug, Topotecan, to the Usual Treatment for Types II and III Pleuropulmonary Blastoma

Phase 3 Recruiting

Pleuropulmonary blastoma

NCT02193282 2026-05-04

Erlotinib Hydrochloride in Treating Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been Completely Removed by Surgery (An ALCHEMIST Treatment Trial)

Phase 3 Active not recruiting

Carcinoma, Non-Small-Cell Lung

NCT03055013 2026-05-04

Nivolumab in Treating Patients With Localized Kidney Cancer Undergoing Nephrectomy

Phase 3 Active not recruiting

819 enrolled 12 charts

Carcinoma, Renal Cell

NCT06745024 2026-05-04

Comparing Radiation Therapy to Usual Treatment for Patients With High-Risk Bone Metastases That Are Not Causing Pain, PREEMPT Trial

Phase 3 Active not recruiting

Neoplasm Metastasis

NCT06958328 2026-05-04

LAP100

Phase 3 Recruiting

Gastrointestinal

Pancreatic Neoplasms

NCT01169337 2026-05-01

Lenalidomide or Observation in Treating Patients With Asymptomatic High-Risk Smoldering Multiple Myeloma

Phase 3 Active not recruiting

226 enrolled 16 charts

Smoldering Multiple Myeloma

NCT03737981 2026-05-01

Testing the Addition of a New Anti-cancer Drug, Venetoclax, to the Usual Treatment (Ibrutinib and Obinutuzumab) in Untreated, Older Patients With Chronic Lymphocytic Leukemia

Phase 3 Active not recruiting

465 enrolled 11 charts

LymphoidOther hematologic neoplasm

Leukemia, Lymphocytic, Chronic, B-Cell

NCT01096368 2026-04-30

Maintenance Chemotherapy or Observation Following Induction Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Ependymoma

Phase 3 Completed

479 enrolled 24 charts

Ependymoma

NCT00003641 2026-02-25

High-Dose Interferon Alfa in Treating Patients With Stage II or Stage III Melanoma

Phase 3 Active not recruiting

1,150 enrolled 6 charts

Melanoma

NCT05717166 2025-12-31

SABR-SYNC

Phase 3 Recruiting

Neoplasm Metastasis

NCT04442048 2025-12-30

COV-IMMUNO

Phase 3 Completed

COVID-19, Neoplasms

NCT03533582 2025-12-22

Cisplatin and Combination Chemotherapy in Treating Children and Young Adults With Hepatoblastoma or Liver Cancer After Surgery

Phase 3 Active not recruiting

Gastrointestinal

Fibrolamellar hepatocellular carcinoma, Hepatoblastoma

NCT03418961 2025-10-08

S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity

Phase 3 Recruiting

Brain Neoplasms, Breast Neoplasms, Cardiotoxicity

NCT04229979 2025-10-01

REGAL

Phase 3 Active not recruiting

Other hematologic neoplasm

Pathologic Complete Response, Leukemia, Myeloid, Acute

NCT03721341 2025-09-18

SABR-COMET 10

Phase 3 Active not recruiting

Neoplasm Metastasis

NCT02085408 2024-12-13

Clofarabine or Daunorubicin Hydrochloride and Cytarabine Followed By Decitabine or Observation in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia

Phase 3 Completed

727 enrolled 13 charts

Other hematologic neoplasm

Congenital Abnormalities, Leukemia, Erythroblastic, Acute, Leukemia, Megakaryoblastic, Acute, Leukemia, Monocytic, Acute, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Acute

NCT00877214 2024-08-22

MAINTAIN

Phase 3 Active not recruiting

LymphoidOther hematologic neoplasm

Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, Mantle-Cell

NCT03723941 2024-08-01

ACACIA

Phase 3 Completed

Adrenocortical Carcinoma

NCT02135419 2024-07-26

ANCHOR

Phase 3 Completed

4,446 enrolled 13 charts

GastrointestinalGynecologic

Squamous Intraepithelial Lesions, Acquired Immunodeficiency Syndrome, Anus Neoplasms, HIV Infections, Papillomavirus Infections

NCT02355379 2024-07-08

ADAGE

Phase 3 Recruiting

Gastrointestinal

Colonic Neoplasms

NCT06313567 2024-07-08

Metronomic Capecitabine in Stage III Gastric Cancer

Phase 3 Recruiting

Gastrointestinal

Stomach Neoplasms

NCT02109146 2024-05-29

Postoperative TACE(Transhepatic Arterial Chemotherapy And Embolization) for Patients With Hepatocellular Carcinoma

Phase 3 Completed

Gastrointestinal

Carcinoma, Hepatocellular

NCT00093470 2024-03-20

Tipifarnib in Treating Patients With Acute Myeloid Leukemia in Remission

Phase 3 Completed

144 enrolled 8 charts

Classical hematologyOther hematologic neoplasm

Anemia, Refractory, with Excess of Blasts, Leukemia, Erythroblastic, Acute, Leukemia, Megakaryoblastic, Acute, Leukemia, Monocytic, Acute, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Acute

NCT03469674 2023-10-11

PORTEC-4a

Phase 3 Active not recruiting

Endometrial Neoplasms

NCT00548756 2023-06-07

Randomized Trial Comparing Radiosurgery With vs Without Whole Brain Radiotherapy

Phase 3 Completed

Brain Neoplasms

NCT00033293 2023-04-18

Cyclophosphamide and Prednisone With or Without Immunoglobulin in Treating Abnormal Muscle Movement in Children With Neuroblastoma

Phase 3 Completed

53 enrolled 14 charts

Neuroblastoma

NCT05524389 2022-11-23

Study of Early Stage Endometrial Cancer Based on Molecular Classification and Traditional Risk Stratification to Guide Adjuvant Radiotherapy Decisions

Phase 3 Not yet recruiting

Endometrial Neoplasms

NCT02063685 2022-06-21

Study to Evaluate the Efficacy of Response-adapted Strategy in Follicular Lymphoma

Phase 3 Completed

Lymphoma, Follicular

NCT00346164 2022-04-28

Observation, Radiation Therapy, Combination Chemotherapy, and/or Surgery in Treating Young Patients With Soft Tissue Sarcoma

Phase 3 Completed

588 enrolled 22 charts

Malignant mesenchymal tumor, Hemangiopericytoma, Malignant, Chondrosarcoma, Extraskeletal Myxoid, Fibrosarcoma, Hemangiosarcoma, Leiomyosarcoma, Liposarcoma, Sarcoma, Sarcoma, Synovial, Dermatofibrosarcoma, Sarcoma, Alveolar Soft Part, Neurofibrosarcoma, Histiocytoma, Malignant Fibrous

NCT00075829 2021-11-01

BMT CTN 0102

Phase 3 Completed

710 enrolled 19 charts

Multiple Myeloma, Neoplasms, Plasma Cell

NCT00108745 2021-09-30

Paclitaxel, Polyglutamate Paclitaxel, or Observation in Treating Patients With Stage III or Stage IV Ovarian Epithelial, Peritoneal Cancer, or Fallopian Tube Cancer

Phase 3 Unknown

1,157 enrolled 15 charts

Brenner Tumor, Fallopian Tube Neoplasms

NCT03199989 2020-03-06

EPAC1

Phase 3 Unknown

Gastrointestinal

Colonic Neoplasms

NCT01039376 2019-07-30

PROLONG

Phase 3 Terminated

480 enrolled 30 charts

LymphoidOther hematologic neoplasm

Leukemia, B-Cell

NCT00300586 2019-05-28

IFCT-GFPC 05.02 A Randomized Phase III Trial Assessing in Patients With Advanced Non-small Cell Lung Cancer

Phase 3 Completed

Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis

NCT00870701 2018-08-22

Observation Versus Post-surgery Radiotherapy After Complete Exeresis in Soft Tissues Members Sarcoma

Phase 3 Terminated

Sarcoma

NCT00048997 2018-06-08

Radiation Therapy in Preventing Central Nervous System (CNS) Metastases in Patients With Non-Small Cell Lung Cancer

Phase 3 Completed

356 enrolled 15 charts

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT00921414 2018-04-27

Mantel Cell Lymphoma Efficacy of Rituximab Maintenance

Phase 3 Completed

Lymphoma, Mantle-Cell

NCT03016000 2017-07-28

Thalidomide Maintenance Treatment in DLBCL

Phase 3 Unknown

Lymphoma, Large B-Cell, Diffuse