Clinical Trials Browser

Phase 1/2 × Panobinostat × Clear all

NCT01582009 2022-08-15

Panobinostat and Everolimus in Treating Patients With Metastatic or Unresectable Renal Cell Cancer That Does Not Respond to Treatment With Sunitinib Malate or Sorafenib Tosylate

Phase 1/2 Terminated

26 enrolled 11 charts

Carcinoma, Renal Cell

NCT01496118 2022-02-02

Study of the Combination of Panobinostat and Carfilzomib in Patients With Relapsed/Refractory Multiple Myeloma

Phase 1/2 Completed

80 enrolled 20 charts

Multiple Myeloma

NCT01169636 2021-01-06

Panobinostat Plus Ifosfamide, Carboplatin, and Etoposide (ICE) Compared With ICE For Relapsed Hodgkin Lymphoma

Phase 1/2 Completed

62 enrolled 13 charts

Hodgkin Disease

NCT00621244 2021-01-05

A Study of Oral LBH589 in Adult Patients With Advanced Hematological Malignancies

Phase 1/2 Completed

175 enrolled 25 charts

LymphoidOther hematologic neoplasmPlasma cell

Leukemia, Lymphoma, Multiple Myeloma

NCT00946647 2020-08-04

A Phase Ib/IIb, Open-label, Multi-center, Study of Oral Panobinostat Administered With 5-Azacitidine (in Adult Patients With Myelodysplastic Syndromes (MDS), Chronic Myelomonocytic Leukemia (CMML), or Acute Myeloid Leukemia (AML).

Phase 1/2 Completed

113 enrolled 21 charts

MyeloidOther hematologic neoplasm

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic

NCT00918333 2020-03-10

Panobinostat and Everolimus in Treating Patients With Recurrent Multiple Myeloma, Non-Hodgkin Lymphoma, or Hodgkin Lymphoma

Phase 1/2 Completed

124 enrolled 10 charts

DermatologicLymphoidOther hematologic neoplasmPlasma cell

Burkitt Lymphoma, Hodgkin Disease, Immunoblastic Lymphadenopathy, Lymphoma, Follicular, Waldenstrom Macroglobulinemia, Multiple Myeloma, Mycosis Fungoides, Sezary Syndrome, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, Large B-Cell, Diffuse, Lymphoma, T-Cell, Cutaneous, Lymphoma, Large-Cell, Anaplastic, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Lymphoma, Extranodal NK-T-Cell

NCT02057640 2019-12-11

MLN9708 (Ixazomib) in Combination With Panobinostat and Dexamethasone in Multiple Myeloma

Phase 1/2 Completed

16 enrolled 12 charts

Multiple Myeloma

NCT00840346 2018-12-11

PANOBIDARA

Phase 1/2 Completed

Other hematologic neoplasm

Leukemia, Myeloid, Acute

NCT01451268 2018-03-20

PANOBEST

Phase 1/2 Unknown

MyeloidOther hematologic neoplasm

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute

NCT00878436 2018-02-07

Safety and Efficacy Studies of Panobinostat and Bicalutamide in Patients With Recurrent Prostate Cancer After Castration

Phase 1/2 Completed

52 enrolled 8 charts

Prostatic Neoplasms, Bulbo-Spinal Atrophy, X-Linked

NCT00925132 2017-07-02

Treatment of Resistant Metastatic Melanoma Using Decitabine, Temozolomide and Panobinostat

Phase 1/2 Terminated

39 enrolled 8 charts

Melanoma, Neoplasm Metastasis

NCT01105312 2017-06-27

Panobinostat and Letrozole in Treating Patients With Metastatic Breast Cancer

Phase 1/2 Completed

28 enrolled 13 charts

Breast Neoplasms, Breast Neoplasms, Male, Triple Negative Breast Neoplasms

NCT02802163 2017-04-25

Induction Therapy for Multiple Myeloma With Carfilzomib, Lenalidomide,Dexamethasone,Panobinostat

Phase 1/2 Withdrawn

Multiple Myeloma

NCT00859222 2017-03-14

LBH589 and Bevacizumab in Patients With Recurrent High Grade Glioma

Phase 1/2 Completed

51 enrolled 18 charts

Glioma

NCT00691938 2016-10-13

LBH589 Plus Decitabine for Myelodysplastic Syndromes (MDS) or Acute Myeloid Leukemia (AML)

Phase 1/2 Completed

52 enrolled 18 charts

MyeloidOther hematologic neoplasm

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute

NCT00567879 2016-05-09

A Trial of Panobinostat and Trastuzumab for Adult Female Patients With HER2 Positive Metastatic Breast Cancer (MBC) Whose Disease Has Progressed on or After Trastuzumab

Phase 1/2 Terminated

56 enrolled 5 charts

Breast Neoplasms

NCT02145715 2015-06-26

MUKsix

Phase 1/2 Unknown

Multiple Myeloma

NCT01298934 2015-03-06

LBH589 (Panobinostat) for the Treatment of Myelofibrosis

Phase 1/2 Unknown

Polycythemia Vera, Primary Myelofibrosis

NCT00967044 2015-02-26

Panobinostat (LBH589) Plus Everolimus (RAD001) in Patients With Relapsed and Refractory Lymphoma

Phase 1/2 Completed

31 enrolled 6 charts

Hodgkin Disease, Lymphoma, Lymphoma, Non-Hodgkin, Recurrence

NCT01194908 2015-01-26

Re-expression of ER in Triple Negative Breast Cancers

Phase 1/2 Terminated

5 enrolled 5 charts

Breast Neoplasms

NCT00743288 2014-05-08

Melphalan and Panobinostat (LBH589) for the Treatment of Patients With Recurrent Multiple Myeloma

Phase 1/2 Completed

40 enrolled 10 charts

Multiple Myeloma