Non-Invasive Focused Ultrasound (FUS) With Oral Panobinostat in Children With Progressive Diffuse Midline Glioma (DMG)
Phase 1 Terminated
5 enrolled 11 charts
Panobinostat and Stereotactic Radiation Therapy in Treating Patients With Brain Tumors
Phase 1 Terminated
17 enrolled
Panobinostat, Gemcitabine Hydrochloride, Busulfan, and Melphalan Before Stem Cell Transplant in Treating Patients With Refractory or Relapsed Multiple Myeloma
Phase 2 Completed
83 enrolled 11 charts
NORTH
Phase 2 Terminated
25 enrolled
Panobinostat in Combination With Daratumumab, Bortezomib and Dexamethasone for the Treatment of Relapsed/Refractory Multiple Myeloma
Phase 1 Terminated
1 enrolled
Serial Measurements of Molecular and Architectural Responses to Therapy (SMMART) PRIME Trial
Phase 1 Terminated
2 enrolled
DIPG
Phase 1 Terminated
4 enrolled
Panobinostat and Carfilzomib in Treating Participants With Relapsed or Refractory Multiple Myeloma
Phase 1 Completed
63 enrolled
A Phase II Study of Oral Panobinostat (LBH589) and Rituximab to Treat Diffuse Large B Cell Lymphoma (DLBCL)
Phase 2 Completed
42 enrolled
EVIDENT
Phase 2 Recruiting
40 enrolled
Panobinostat Maintenance After HSCT fo High-risk AML and MDS
Phase 3 Terminated
52 enrolled
Phase I of Histone Deacetylase (HDAC) Inhibitor Panobinostat With Ipilimumab With Unresectable III/IV Melanoma
Phase 1 Completed
17 enrolled 12 charts
Panobinostat (LBH589): Multiple Myeloma - Autologous Hematopoietic Cell Transplantation (HCT)
Phase 2 Completed
30 enrolled 12 charts
Panobinostat and Everolimus in Treating Patients With Metastatic or Unresectable Renal Cell Cancer That Does Not Respond to Treatment With Sunitinib Malate or Sorafenib Tosylate
Phase 1/2 Terminated
26 enrolled 11 charts
Panobinostat in Treating Patients With Relapsed or Refractory Non-Hodgkin Lymphoma
Phase 2 Completed
41 enrolled 8 charts
Panobinostat, Carfilzomib, and Dexamethasone in Patients With Relapsed or Refractory Multiple Myeloma
Phase 2 Terminated
9 enrolled 12 charts
VEG VCA1
Phase 2 Completed
30 enrolled
Study of the Combination of Panobinostat and Carfilzomib in Patients With Relapsed/Refractory Multiple Myeloma
Phase 1/2 Completed
80 enrolled 20 charts
LBH589 Treatment for Refractory Clear Cell Renal Carcinoma
Phase 2 Completed
20 enrolled 7 charts
PanRVD
Phase 1 Completed
21 enrolled
LBH589 in Relapsed or Relapsed and Refractory Waldenstrom's Macroglobulinemia
Phase 2 Completed
39 enrolled 13 charts
Panobinostat Plus Ifosfamide, Carboplatin, and Etoposide (ICE) Compared With ICE For Relapsed Hodgkin Lymphoma
Phase 1/2 Completed
62 enrolled 13 charts
Sorafenib and LBH589 in Hepatocellular Carcinoma (HCC)
Phase 1 Terminated
2 enrolled
Panobinostat and Everolimus in Treating Patients With Recurrent Multiple Myeloma, Non-Hodgkin Lymphoma, or Hodgkin Lymphoma
Phase 1/2 Completed
124 enrolled 10 charts
MLN9708 (Ixazomib) in Combination With Panobinostat and Dexamethasone in Multiple Myeloma
Phase 1/2 Completed
16 enrolled 12 charts
Study of Panobinostat in Patients With Neuroendocrine Tumors
Phase 2 Terminated
15 enrolled 11 charts
Trial of LBH589 in Metastatic Thyroid Cancer
Phase 2 Completed
13 enrolled 11 charts
FIL_PanAL10
Phase 2 Completed
35 enrolled 10 charts
PDR001 + Panobinostat for Melanoma and NSCLC
Phase 1 Withdrawn
A Study of Panobinostat in Combination With Everolimus for Children and Young Adults With Gliomas
Phase 2 Withdrawn
Phase I Dose Finding and Proof-of-concept Study of Panobinostat With Standard Dose Cytarabine and Daunorubicin for Untreated Acute Myeloid Leukemia or Advanced Myelodysplastic Syndrome
Phase 1 Completed
29 enrolled
Re-Induction Therapy for Relapsed Pediatric T-Cell Acute Lymphoblastic Leukemia or Lymphoma
Phase 2 Terminated
3 enrolled 6 charts
Combination Therapy of Lenalidomide/Bortezomib/Dexamethasone and Panobinostat in Transplant Eligible New Diagnosed Multiple Myeloma (MM) Patients
Phase 1 Completed
77 enrolled
Study of the Combination of Panobinostat & Carfilzomib in Patients With Relapsed &/or Refractory Multiple Myeloma
Phase 1 Completed
32 enrolled
PANOBIDARA
Phase 1/2 Completed
46 enrolled
Panobinostat With Fludarabine and Cytarabine for Treatment of Children With Acute Myeloid Leukemia or Myelodysplastic Syndrome
Phase 1 Terminated
19 enrolled
Study of LBH589 for Patients With Low or Intermediate-1 Risk Myelodysplastic Syndrome (MDS)
Phase 2 Terminated
17 enrolled 5 charts
Safety and Tolerability Study of RAD001 and LBH589 in All Solid Tumors With Enrichment for EBV Driven Tumors
Phase 1 Unknown
49 enrolled
Phase II, Single-Center, Oral Panobinostat in Combination With Lenalidomide and Dexamethasone in Multiple Myeloma (MM)
Phase 2 Completed
32 enrolled 21 charts
PANOBEST
Phase 1/2 Unknown
62 enrolled
Safety and Efficacy Studies of Panobinostat and Bicalutamide in Patients With Recurrent Prostate Cancer After Castration
Phase 1/2 Completed
52 enrolled 8 charts
Study of Cisplatin and Pemetrexed in Combination With Panobinostat in Solid Tumors
Phase 1 Completed
23 enrolled
Panobinostat & Bortezomib in Pancreatic Cancer Progressing on Gemcitabine Therapy
Phase 2 Terminated
7 enrolled 8 charts
A Phase II Trial of Panobinostat and Lenalidomide in Patients With Relapsed or Refractory Hodgkin's Lymphoma
Phase 2 Completed
24 enrolled 7 charts
Treatment of Resistant Metastatic Melanoma Using Decitabine, Temozolomide and Panobinostat
Phase 1/2 Terminated
39 enrolled 8 charts
Panobinostat and Letrozole in Treating Patients With Metastatic Breast Cancer
Phase 1/2 Completed
28 enrolled 13 charts
Carboplatin and Etoposide Plus LBH589 for Small Cell Lung Cancer
Phase 1 Terminated
7 enrolled
Panobinostat With Rituximab for Relapsed/Refractory Diffuse Large B Cell Lymphoma
Phase 2 Terminated
18 enrolled 20 charts
Induction Therapy for Multiple Myeloma With Carfilzomib, Lenalidomide,Dexamethasone,Panobinostat
Phase 1/2 Withdrawn
Panobinostat Combined With High-Dose Gemcitabine/Busulfan/Melphalan With Autologous Stem Cell Transplant for Patients With Refractory/Relapsed Lymphoma
Phase 2 Withdrawn