Clinical Trials

314 enrolled

Carcinoma, Non-Small-Cell Lung

NCT05469178 2025-10-29

A Clinical Study of Bemcentinib With Standard of Care Chemoimmunotherapy in Untreated Advanced/Metastatic Non-small Cell Lung Cancer Patients With a Mutation in the STK11 Gene

26 enrolled 13 charts

Carcinoma, Non-Small-Cell Lung

NCT05407675 2025-10-03

A Study to Evaluate the Safety and Tolerability of BMS-986408 Alone and in Combination With Nivolumab or Nivolumab and Ipilimumab in Participants With Advanced Solid Tumors

68 enrolled 27 charts

Tumor-Agnostic

Neoplasms

NCT04956640 2025-09-25

Study of LY3537982 in Cancer Patients With a Specific Genetic Mutation (KRAS G12C)

GastrointestinalGynecologicThoracic

540 enrolled

Biliary Tract Neoplasms, Carcinoma, Non-Small-Cell Lung, Ovarian Neoplasms, Pancreatic Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms

NCT06385678 2025-09-19

A Study of HRS-4642 in Patients With Advanced Solid Tumors Harboring KRAS G12D Mutation

Phase 1/2 Active not recruiting

47 enrolled

Other solid neoplasm

Advanced KRAS G12D Mutant Solid Tumors

NCT07157956 2025-09-05

CVL006-T1002

Phase 1/2 Not yet recruiting

318 enrolled

Other solid neoplasm

Advanced Solid Tumor

NCT07070440 2025-08-29

DZD6008 Combination Therapy in Patients With Locally Advanced or Metastatic NSCLC With EGFR Mutation (TIAN-SHAN7)

100 enrolled

Carcinoma, Non-Small-Cell Lung

NCT04717375 2025-08-07

Study of SAR444881 Administered Alone and in Combination With Other Therapeutics in Participants With Advanced Solid Tumors

125 enrolled

Tumor-Agnostic

Neoplasms

NCT05315700 2025-08-05

Study of ORIC-114 in Patients With Advanced Solid Tumors Harboring an EGFR or HER2 Alteration

Phase 1/2 Active not recruiting

350 enrolled

Breast

Breast Neoplasms

NCT05180799 2025-06-15

A Phase 1/2 Study of BA3071 in Patients With Solid Tumors

320 enrolled

Dermatologic

Melanoma, Neoplasm Metastasis, Neoplasms

NCT06943820 2025-06-03

AK129 Combination Therapy for Advanced Solid Tumors

Phase 1/2 Active not recruiting

230 enrolled

Head & Neck

Squamous Cell Carcinoma of Head and Neck

NCT03970746 2025-05-29

Safety, Immunogenicity and Preliminary Clinical Activity Study of PDC*lung01 Cancer Vaccine in NSCLC

73 enrolled

Carcinoma, Non-Small-Cell Lung

NCT05431270 2025-01-31

Dose Escalation/Expansion Study of Mavrostobart (PT199), an Anti-CD73 MAb, Administered Alone and in Combination with a PD-1 Inhibitor or Chemotherapy (the MORNINGSTAR Study)

40 enrolled

Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis

NCT06758557 2025-01-23

A Study to Evaluate the Safety and Efficacy of HB0025 Injection in Patients With Advanced Solid Tumor

282 enrolled

Gynecologic

Endometrial Neoplasms

NCT03267316 2024-08-22

CANFOUR

BreastGastrointestinalThoracic

167 enrolled

Carcinoma, Non-Small-Cell Lung, Neoplasms, Colorectal Neoplasms, Triple Negative Breast Neoplasms

NCT04647344 2024-04-25

A Study of AK104 in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer

46 enrolled

Lung Cancer Non-Small Cell Stage IIIB/IIIC/IV

NCT02439450 2023-09-21

A Study of Combination Therapies With Viagenpumatucel-L (HS-110) in Patients With Non-Small Cell Lung Cancer

121 enrolled 11 charts

Carcinoma, Non-Small-Cell Lung, Neoplasms

NCT03317496 2023-08-29

Safety And Efficacy Study Of Avelumab Plus Chemotherapy With Or Without Other Anti-Cancer Immunotherapy Agents In Patients With Advanced Malignancies

67 enrolled 24 charts

Carcinoma, Non-Small-Cell Lung

NCT03840915 2023-08-21

M7824 in Combination With Chemotherapy in Stage IV Non-small Cell Lung Cancer (NSCLC)

70 enrolled 17 charts

Carcinoma, Non-Small-Cell Lung

NCT01126736 2023-06-22

Eribulin Mesylate Administered in Combination With Pemetrexed Versus Pemetrexed Alone as Second Line Therapy in Patients With Stage IIIB or IV Nonsquamous Non Small Cell Lung Cancer

98 enrolled 15 charts

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT05794477 2023-06-02

A Study of SHR-1802 in Combination With Adebrelimab in Patients With Advanced Solid Tumors

Phase 1/2 Unknown

132 enrolled

Other solid neoplasm

Advanced Solid Tumor

NCT02983045 2023-03-13

PIVOT-02

BreastDermatologicGastrointestinalGenitourinaryThoracic

557 enrolled 22 charts

Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Melanoma, Neoplasm Metastasis, Stomach Neoplasms, Colorectal Neoplasms, Triple Negative Breast Neoplasms

NCT03138889 2023-03-10

PROPEL

162 enrolled 21 charts

Carcinoma, Non-Small-Cell Lung

NCT01982955 2022-11-08

Tepotinib With Gefitinib in Participants With Locally Advanced or Metastatic NSCLC (INSIGHT)

88 enrolled 45 charts

Carcinoma, Non-Small-Cell Lung

NCT02039674 2022-11-08

MK-3475-021

267 enrolled 24 charts

Carcinoma, Non-Small-Cell Lung

NCT03085914 2022-09-23

A Study of Epacadostat in Combination With Pembrolizumab and Chemotherapy in Participants With Advanced or Metastatic Solid Tumors (ECHO-207/KEYNOTE-723)

70 enrolled 17 charts

GastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Colorectal Neoplasms

NCT03562871 2022-04-21

IO102 With Pembrolizumab, With or Without Chemotherapy, as First-line Treatment of Metastatic NSCLC

109 enrolled

NSCLC

NCT02347917 2022-04-12

A Study of BBI608 in Combination With Pemetrexed and Cisplatin in Adult Patients With Malignant Pleural Mesothelioma

Other solid neoplasmThoracic

28 enrolled 23 charts

Mesothelioma, Malignant, Carcinoma, Non-Small-Cell Lung

NCT04430933 2021-08-18

A Safety and Tolerability Study of NC318 in Combination With Chemotherapy for Subjects With Advanced or Metastatic NSCLC

Phase 1/2 Withdrawn

Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis

NCT00700336 2021-07-20

Study of CBP501 + Pemetrexed + Cisplatin on MPM (Phase I/II)