Clinical Trials Browser

Phase 1/2 × Completed × Pemetrexed × Clear all

NCT05664971 2025-12-02

JS004 Combined With Toripalimab and With Standard Chemotherapy Treat Patients With Advanced Lung Cancer

Phase 1/2 Completed

Advanced Lung Cancer

NCT05407675 2025-10-03

A Study to Evaluate the Safety and Tolerability of BMS-986408 Alone and in Combination With Nivolumab or Nivolumab and Ipilimumab in Participants With Advanced Solid Tumors

Phase 1/2 Completed

68 enrolled 27 charts

Neoplasms

NCT05289908 2025-05-04

Intrathecal Pemetrexed for Leptomeningeal Metastasis

Phase 1/2 Completed

Meningeal Carcinomatosis

NCT03267316 2024-08-22

CANFOUR

Phase 1/2 Completed

BreastGastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Neoplasms, Colorectal Neoplasms, Triple Negative Breast Neoplasms

NCT04647344 2024-04-25

A Study of AK104 in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer

Phase 1/2 Completed

Lung Cancer Non-Small Cell Stage IIIB/IIIC/IV

NCT02439450 2023-09-21

A Study of Combination Therapies With Viagenpumatucel-L (HS-110) in Patients With Non-Small Cell Lung Cancer

Phase 1/2 Completed

121 enrolled 11 charts

Carcinoma, Non-Small-Cell Lung, Neoplasms

NCT03840915 2023-08-21

M7824 in Combination With Chemotherapy in Stage IV Non-small Cell Lung Cancer (NSCLC)

Phase 1/2 Completed

70 enrolled 17 charts

Carcinoma, Non-Small-Cell Lung

NCT01126736 2023-06-22

Eribulin Mesylate Administered in Combination With Pemetrexed Versus Pemetrexed Alone as Second Line Therapy in Patients With Stage IIIB or IV Nonsquamous Non Small Cell Lung Cancer

Phase 1/2 Completed

98 enrolled 15 charts

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT02983045 2023-03-13

PIVOT-02

Phase 1/2 Completed

557 enrolled 22 charts

BreastDermatologicGastrointestinalGenitourinaryThoracic

Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Melanoma, Neoplasm Metastasis, Stomach Neoplasms, Colorectal Neoplasms, Triple Negative Breast Neoplasms

NCT01982955 2022-11-08

Tepotinib With Gefitinib in Participants With Locally Advanced or Metastatic NSCLC (INSIGHT)

Phase 1/2 Completed

88 enrolled 45 charts

Carcinoma, Non-Small-Cell Lung

NCT02039674 2022-11-08

MK-3475-021

Phase 1/2 Completed

267 enrolled 24 charts

Carcinoma, Non-Small-Cell Lung

NCT03085914 2022-09-23

A Study of Epacadostat in Combination With Pembrolizumab and Chemotherapy in Participants With Advanced or Metastatic Solid Tumors (ECHO-207/KEYNOTE-723)

Phase 1/2 Completed

70 enrolled 17 charts

GastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Colorectal Neoplasms

NCT03562871 2022-04-21

IO102 With Pembrolizumab, With or Without Chemotherapy, as First-line Treatment of Metastatic NSCLC

Phase 1/2 Completed

NSCLC

NCT02347917 2022-04-12

A Study of BBI608 in Combination With Pemetrexed and Cisplatin in Adult Patients With Malignant Pleural Mesothelioma

Phase 1/2 Completed

28 enrolled 23 charts

Other solid neoplasmThoracic

Mesothelioma, Malignant, Carcinoma, Non-Small-Cell Lung

NCT00700336 2021-07-20

Study of CBP501 + Pemetrexed + Cisplatin on MPM (Phase I/II)

Phase 1/2 Completed

69 enrolled 9 charts

Other solid neoplasmThoracic

Mesothelioma, Malignant

NCT02574078 2021-05-06

CheckMate370

Phase 1/2 Completed

341 enrolled 28 charts

Carcinoma, Non-Small-Cell Lung

NCT01397305 2020-09-09

An Extended Feasibility Phase I/II Study of Methylenetetrahydrofolate (Arfolitixorin) and Pemetrexed Single Agent, Given as Neoadjuvant Treatment in Patients With Resectable Rectal Cancer

Phase 1/2 Completed

Gastrointestinal

Digestive System Diseases, Digestive System Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Neoplasms, Neoplasms by Site, Rectal Diseases, Rectal Neoplasms, Colorectal Neoplasms

NCT03507244 2019-12-26

Concurrent Intrathecal-pemetrexed and Involved-field Radiotherapy for Leptomeningeal Metastasis From Solid Tumors

Phase 1/2 Completed

Meningeal Carcinomatosis

NCT00389805 2018-10-31

Bortezomib and Pemetrexed Disodium in Treating Patients With Advanced Non-Small Cell Lung Cancer or Other Solid Tumors

Phase 1/2 Completed

27 enrolled 7 charts

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT01139775 2018-05-18

A Study in Non Small Cell Lung Cancer

Phase 1/2 Completed

76 enrolled 24 charts

Other solid neoplasmThoracic

Carcinoma, Carcinoma, Non-Small-Cell Lung, Mesothelioma

NCT01211275 2017-02-28

N08CPA

Phase 1/2 Completed

Other solid neoplasmThoracic

Mesothelioma, Malignant, Mesothelioma

NCT00059865 2016-12-07

Gemcitabine Plus Pemetrexed Disodium in Treating Patients With Unresectable or Metastatic Biliary Tract or Gallbladder Cancer

Phase 1/2 Completed

Gastrointestinal

Bile Duct Neoplasms, Gallbladder Neoplasms, Liver Neoplasms

NCT00216203 2016-09-29

Pemetrexed Plus Cetuximab in Patients With Recurrent Non Small Cell Lung Cancer

Phase 1/2 Completed

36 enrolled 12 charts

Carcinoma, Non-Small-Cell Lung

NCT01666977 2016-06-03

Phase 1b/2 Trial of AMG386 With Pemetrexed and Carboplatin in Non-Small Cell Lung Cancer

Phase 1/2 Completed

Carcinoma, Non-Small-Cell Lung

NCT00768755 2015-10-28

Evaluation Of The Efficacy Of The Combination Of Axitinib With Pemetrexed And Cisplatin In The Treatment Of Non-Squamous Non-Small Cell Lung Cancer

Phase 1/2 Completed

180 enrolled 13 charts

Carcinoma, Non-Small-Cell Lung

NCT00529100 2013-07-09

Concurrent Pemetrexed, Cisplatin and Radiation Therapy in Patients With Stage IIIA/B Non Small Cell Lung Cancer

Phase 1/2 Completed

49 enrolled 18 charts

Carcinoma, Non-Small-Cell Lung

NCT00297089 2013-01-31

A Phase 1/2 Study Evaluating ABT-751 in Combination With Alimta in Advanced Non-Small Cell Lung Cancer

Phase 1/2 Completed

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT00482014 2012-11-27

A Study of Pemetrexed Plus Carboplatin, or Pemetrexed Plus Cisplatin With Radiation Therapy Followed by Pemetrexed in Patients With Inoperable Non-Small-Cell Lung Cancer

Phase 1/2 Completed

120 enrolled 17 charts

Carcinoma, Non-Small-Cell Lung

NCT00408226 2012-01-20

Safety Study of MKC-1 Combined With Pemetrexed to Treat Advanced Cancer and Non-Small Cell Lung Cancer

Phase 1/2 Completed

Carcinoma, Non-Small-Cell Lung

NCT00489359 2011-06-16

Trial of Pemetrexed and Carboplatin in Patients With Recurrent Ovarian or Primary Peritoneal Cancer

Phase 1/2 Completed

86 enrolled 23 charts

Ovarian Neoplasms

NCT00166465 2011-03-14

Stage IV Colorectal CA ALIMTA

Phase 1/2 Completed

Gastrointestinal

Colorectal Neoplasms

NCT00374868 2010-11-04

Pemetrexed Plus Cisplatin Bi-Weekly, in Patients With Urothelial Cancer (Metastatic, Locally Advanced or Non-Resectable)

Phase 1/2 Completed

59 enrolled 17 charts

Urologic Neoplasms

NCT00387322 2010-03-29

Pemetrexed Disodium and Erlotinib in Treating Patients With Advanced Non-Small Cell Lung Cancer or Other Solid Tumors

Phase 1/2 Completed

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT00684099 2009-12-15

Docetaxel/Pemetrexed as 1st Line Treatment in Patients With Non Small Cell Lung Cancer (NSCLC)

Phase 1/2 Completed

Carcinoma, Non-Small-Cell Lung

NCT00190671 2009-11-20

A Study of Pemetrexed and Cyclophosphamide Given Every 21 Days in Advanced Breast Cancer Patients

Phase 1/2 Completed

103 enrolled 19 charts

Breast Neoplasms

NCT00320515 2009-09-28

Study of Pemetrexed Plus Cisplatin in Advanced Gastric Cancer

Phase 1/2 Completed

89 enrolled 12 charts

Gastrointestinal

Stomach Neoplasms

NCT00071136 2007-01-26

Pemetrexed and Gemcitabine in Patients With Advanced Non-Small Cell Lung Cancer (NSCLC)

Phase 1/2 Completed

Lung Neoplasms

NCT00101842 2006-08-29

Gemcitabine and Platinol Followed by Pemetrexed and Gemcitabine in Patients With Advanced or Metastatic Bladder Cancer

Phase 1/2 Completed

Carcinoma, Transitional Cell

NCT00034502 2006-07-19

A Trial of ALIMTA (Pemetrexed) Plus Irinotecan in Patients Who Have Been Previously Treated For Metastatic Colorectal Cancer.

Phase 1/2 Completed

Gastrointestinal

Colorectal Neoplasms

NCT00097383 2006-07-19

Study of Alimta and Epirubicin Administered in Patients With Locally Advanced or Metastatic Breast Cancer

Phase 1/2 Completed

Breast Neoplasms