Clinical Trials

673 enrolled 38 charts

Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis

NCT06280196 2025-12-02

A Study to Evaluate PK, Efficacy, and Safety of BAT3306 Plus Chemo and Compare With Keytruda®(EU/US) in Participants With IV nqNSCLC

162 enrolled

Carcinoma, Non-Small-Cell Lung

NCT04524689 2025-10-29

CARMEN-LC05

57 enrolled 26 charts

Non-squamous Non-small-cell Lung Cancer (NSQ NSCLC)

NCT05469178 2025-10-29

A Clinical Study of Bemcentinib With Standard of Care Chemoimmunotherapy in Untreated Advanced/Metastatic Non-small Cell Lung Cancer Patients With a Mutation in the STK11 Gene

26 enrolled 13 charts

Carcinoma, Non-Small-Cell Lung

NCT04717375 2025-08-07

Study of SAR444881 Administered Alone and in Combination With Other Therapeutics in Participants With Advanced Solid Tumors

125 enrolled

Tumor-Agnostic

Neoplasms

NCT03777124 2025-07-04

Phase II Study of SHR-1210(Anti-PD-1 Antibody) Combination With Apatinib Versus Pemetrexed and Carboplatin in Subjects With KRAS Mutant Stage IV Non-squamous Non-small Cell Lung Cancer

25 enrolled

Carcinoma, Non-Small-Cell Lung

NCT02093962 2025-05-16

Study of TH-302 or Placebo in Combination With Pemetrexed in Patients With Non-squamous Non-small Cell Lung Cancer

265 enrolled 8 charts

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT06094296 2025-04-16

A Study of BMS-986315 and Nivolumab in Combination With Chemotherapy in Participants With First-line Stage IV or Recurrent Non-small Cell Lung Cancer (NSCLC)

1 enrolled 4 charts

Lung Neoplasms

NCT04786964 2025-04-02

CONTERNO

25 enrolled 10 charts

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm Metastasis

NCT00979576 2025-03-06

BIBF 1120 in Combination With Pemetrexed in Advanced Non Small Cell Lung Cancer (NSCLC)

19 enrolled 16 charts

Carcinoma, Non-Small-Cell Lung

NCT05241873 2025-02-10

(Concerto) Study of BLU-451 in Advanced Cancers With EGFR Exon 20 Insertion Mutations

103 enrolled

CNSThoracic

Adenocarcinoma, Brain Neoplasms, Bronchial Neoplasms, Carcinoma, Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, Lung Diseases, Lung Neoplasms, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Thoracic Neoplasms

NCT05583188 2024-07-19

VIGOR

Phase 4 Terminated

5 enrolled

Lung Diseases, Lung Neoplasms, Thoracic Neoplasms

NCT05493501 2024-05-02

Aumolertinib With Chemotherapy or Alone Compared With Osimertinib in Patients With Epidermal Growth Factor Receptor-Mutant Non-Small Cell Lung Cancer

8 enrolled 7 charts

NSCLC

NCT03866980 2024-04-03

A Study of Anti-PD-1 AK105 in Patients With Metastatic Nonsquamous Non-small Cell Lung Cancer

164 enrolled

Carcinoma, Non-Small-Cell Lung

NCT04816214 2024-03-05

GEOMETRY-E

6 enrolled 20 charts

Carcinoma, Carcinoma, Non-Small-Cell Lung

NCT02654587 2024-02-02

ATALANTE-1

219 enrolled 22 charts

Carcinoma, Non-Small-Cell Lung

NCT03840902 2024-01-16

M7824 With cCRT in Unresectable Stage III Non-small Cell Lung Cancer (NSCLC)

153 enrolled 13 charts

Carcinoma, Non-Small-Cell Lung

NCT03317496 2023-08-29

Safety And Efficacy Study Of Avelumab Plus Chemotherapy With Or Without Other Anti-Cancer Immunotherapy Agents In Patients With Advanced Malignancies

67 enrolled 24 charts

Carcinoma, Non-Small-Cell Lung

NCT05153408 2023-06-18

(HARMONY) Study of BLU-701 in EGFR-mutant NSCLC

20 enrolled

Adenocarcinoma, Bronchial Neoplasms, Carcinoma, Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, Lung Diseases, Lung Neoplasms, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Nerve Tissue, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Thoracic Neoplasms

NCT03138889 2023-03-10

PROPEL

162 enrolled 21 charts

Carcinoma, Non-Small-Cell Lung

NCT03838848 2023-03-02

KN046 in Patients With Advanced Non-small Cell Lung Cancer

120 enrolled

Carcinoma, Non-Small-Cell Lung

NCT04022876 2022-10-10

A Study of ALRN-6924 for the Prevention of Chemotherapy-induced Side Effects (Chemoprotection)

35 enrolled

Carcinoma, Non-Small-Cell Lung, Small Cell Lung Carcinoma

NCT04861948 2022-10-04

IBI188 Combination Therapy in Solid Tumors

9 enrolled

SarcomaThoracic

Adenocarcinoma of Lung, Osteosarcoma

NCT04265534 2022-09-21

KEAPSAKE

40 enrolled

Carcinoma, Non-Small-Cell Lung

NCT03064854 2022-08-15

PDR001 in Combination With Platinum-doublet Chemotherapy and Other Immunology Agents in PD-L1 Unselected, Metastatic NSCLC Patients

111 enrolled

Carcinoma, Non-Small-Cell Lung

NCT00794417 2020-12-10

A Study of Aflibercept Administered in Combination With Pemetrexed and Cisplatin in Participants With Advanced Carcinoma

60 enrolled 24 charts

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT00538681 2020-11-05

Study for Participants With Advanced, Not Amenable to Surgery, or Metastatic Lung Cancer Comparing Treatment With Pemetrexed + Cisplatin + Enzastaurin Versus Pemetrexed + Cisplatin + Placebo

35 enrolled 14 charts

Lung Neoplasms

NCT01774578 2020-05-28

Immunotherapy Study in Progressive or Relapsed Non-Small Cell Lung Cancer

Phase 2/3 Terminated

135 enrolled

Carcinoma, Non-Small-Cell Lung, Recurrence

NCT02357147 2020-03-17

ARTEMIS

Other solid neoplasmThoracic

124 enrolled 10 charts

Severe combined immunodeficiency with sensitivity to ionizing radiation, Mesothelioma, Malignant

NCT03460678 2020-03-05

Randomized Comparative Study of Erlotinib and Pemetrexed in the Maintenance Treatment of Advanced Lung Cancer Patients.

Phase 4 Terminated

9 enrolled

Carcinoma, Non-Small-Cell Lung

NCT02117024 2020-02-05

A Phase 2 Study of Viagenpumatucel-L (HS-110) in Patients With Non-Small Cell Lung Cancer

66 enrolled 17 charts

Carcinoma, Non-Small-Cell Lung, Neoplasms

NCT02322281 2019-08-14

TIGER-3: Open Label, Multicenter Study of Rociletinib (CO-1686) Mono Therapy Versus Single-agent Cytotoxic Chemotherapy in Patients With Mutant EGFR NSCLC Who Have Failed at Least One Previous EGFR-Directed TKI and Platinum-doublet Chemotherapy

149 enrolled 17 charts

Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis, Neoplasms, Recurrence

NCT01646125 2019-07-24

An Open-label, Randomized Phase II Study to Evaluate the Efficacy of AUY922 vs Pemetrexed or Docetaxel in NSCLC Patients With EGFR Mutations

59 enrolled 9 charts

Adenocarcinoma of Lung, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT03348904 2019-06-13

Nivolumab and Epacadostat With Platinum Doublet Chemotherapy Versus Platinum Doublet Chemotherapy in Non-Small Cell Lung Cancer

2 enrolled 6 charts

Other solid neoplasmThoracic

Parkinson Disease 4, Autosomal Dominant Lewy Body, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT01907100 2019-03-18

Nintedanib (BIBF 1120) in Mesothelioma

Phase 2/3 Terminated

545 enrolled 15 charts

Mesothelioma

NCT01376310 2019-02-19

GSK1120212 Rollover Study

159 enrolled 9 charts

Tumor-Agnostic

Neoplasms

NCT02119650 2018-02-13

Ruxolitinib in Combination With Pemetrexed/Cisplatin in Non Small Cell Lung Cancer

76 enrolled 13 charts

Carcinoma, Non-Small-Cell Lung

NCT02087241 2017-03-29

Ph II Trial of Carboplatin and Pemetrexed With or Without AZD1775 for Untreated Lung Cancer

22 enrolled 15 charts

Lung Neoplasms

NCT01383148 2017-01-05

TIME

Phase 2/3 Terminated

222 enrolled

Carcinoma, Non-Small-Cell Lung

NCT02083679 2016-10-25

Sym004 in Subjects With Stage IV Non-small Cell Lung Cancer

15 enrolled 10 charts

Carcinoma, Non-Small-Cell Lung

NCT01714037 2015-04-08

HALO

82 enrolled

Carcinoma, Non-Small-Cell Lung

NCT01313663 2014-10-27

A Study to Evaluate Pazopanib in Comparison to Pemetrexed in Maintenance Setting in Non-progressing Subjects With Metastatic Stage IVA and IVB Non-squamous Non-small Cell Lung Cancer (NSCLC) Population

20 enrolled 21 charts