Announcements Trials
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Phase

Phase 3 3Phase 2/3 1

Status

Completed 4

Sponsor Class

OTHER 2NETWORK 2

Study Type

Interventional 4

Sponsor

Cancer Type

Head & Neck 3Other 1Breast 1

Conditions

Head and Neck Neoplasms 3Xerostomia 2Tongue Neoplasms 1Squamous Cell Carcinoma of Head and Neck 1Sexuality 1Sexual Dysfunction, Physiological 1Salivary Gland Neoplasms 1Oropharyngeal Neoplasms 1Neoplasms 1Nasopharyngeal Neoplasms 1Mouth Neoplasms 1Lymphoid Interstitial Pneumonia 1Laryngeal Neoplasms 1Hypopharyngeal Neoplasms 1Breast Neoplasms 1

Interventions

Cyclophosphamide 1499Cisplatin 1435Paclitaxel 1340Radiotherapy 1310Carboplatin 1267Gemcitabine 1226Docetaxel 1133Bevacizumab 1070Fluorouracil 906Doxorubicin 805Dexamethasone 755Rituximab 744Capecitabine 735Oxaliplatin 709pembrolizumab 700Etoposide 679Irinotecan 639Filgrastim 624Cytarabine 587Nivolumab 586Leucovorin 583Vincristine 517Cetuximab 479Prednisone 478Bortezomib 474Trastuzumab 468Erlotinib Hydrochloride 467Surveys and Questionnaires 460Methotrexate 444Lenalidomide 436

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Completed × Pilocarpine × Clear all
NCT00656513 2019-11-19

Acupuncture-Like Transcutaneous Electrical Nerve Stimulation (ALTENS) or Pilocarpine in Treating Early Dry Mouth in Patients Undergoing Radiation Therapy for Head and Neck Cancer

Radiation Therapy Oncology Group

Phase 2/3 Completed
196 enrolled 13 charts
Head & Neck

Head and Neck Neoplasms, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Nasopharyngeal Neoplasms, Oropharyngeal Neoplasms, Salivary Gland Neoplasms, Tongue Neoplasms, Xerostomia

NCT00343382 2016-08-12

Pilocarpine in Treating Vaginal Dryness in Patients With Breast Cancer

Alliance for Clinical Trials in Oncology

Phase 3 Completed
201 enrolled 11 charts
BreastOther

Breast Neoplasms, Sexual Dysfunction, Physiological, Sexuality

NCT00003139 2015-11-17

Pilocarpine in Preventing Mucositis and Dry Mouth in Patients Receiving Radiation Therapy for Head and Neck Cancer

Radiation Therapy Oncology Group

Phase 3 Completed
249 enrolled
Head & Neck

Lymphoid Interstitial Pneumonia, Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT00168181 2011-04-18

Trial Comparing Oral Pilocarpine (Salagen) Versus Submandibular Salivary Gland Transfer Protocol, For the Prevention of Radiation (XRT) Induced Xerostomia in Head and Neck Cancer Patients

AHS Cancer Control Alberta

Phase 3 Completed
220 enrolled
Head & Neck

Head and Neck Neoplasms, Neoplasms, Xerostomia

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