Clinical Trials

Prostatic Neoplasms, Castration-Resistant

NCT02133625 2026-03-30

A Study of Pioglitazone and Carboplatin in Patients With Advanced Solid Tumors

Phase 1 Completed

14 enrolled

Tumor-Agnostic

Neoplasm Metastasis

NCT04794127 2026-02-18

TRABEPIO

Phase 2 Active not recruiting

10 enrolled

Sarcoma

Liposarcoma, Liposarcoma, Myxoid

NCT05919147 2025-07-04

TRACE-1

24 enrolled

Lung Neoplasms

NCT05013255 2025-04-08

Pioglitazone Therapy Targeting Fatigue in Breast Cancer

Phase 2 Recruiting

30 enrolled

Breast

Breast Neoplasms

NCT02852486 2025-03-30

EDI-PIO

31 enrolled

Leukemia, Myelogenous, Chronic, BCR-ABL Positive

NCT02942758 2024-05-08

AML-ViVA

Other hematologic neoplasm

10 enrolled

Leukemia, Myeloid, Acute

NCT05394142 2024-04-22

SPIOMET4HEALTH

Phase 2 Recruiting

364 enrolled

Polycystic Ovary Syndrome

NCT05098327 2023-08-15

Pioglitazone and Insulin Resistance in ADT

Phase 3 Withdrawn

Diabetes Mellitus, Type 2, Insulin Resistance, Prostatic Neoplasms

NCT04995978 2023-06-23

Insulin Resistance and Androgen Deprivation Therapy

Phase 2 Withdrawn

Phase EARLY_PHASE1 Withdrawn

Insulin Resistance, Prostatic Neoplasms

NCT04658849 2023-05-15

Insulin Resistance Following ADT for Prostate CA

Phase EARLY_PHASE1 Recruiting

Insulin Resistance, Prostatic Neoplasms

NCT00203996 2023-03-21

Polycystic Ovary Syndrome (PCOS) and Sleep Apnea

Phase 4 Terminated

37 enrolled 15 charts

Insulin Resistance, Polycystic Ovary Syndrome, Glucose Intolerance, Sleep Apnea, Obstructive, Metabolic Syndrome

NCT05753657 2023-03-03

A Pilot Study of Monitoring Insulin Levels and Treating Hyperinsulinemia and Hyperglycemia With Pioglitazone in Patients Treated With Alpelisib for Metastatic Breast Cancer.

30 enrolled

Breast

Breast Neoplasms, Hyperinsulinism

NCT05519813 2022-08-29

Effects of Pioglitazone Combined With Metformin on Gonadal and Metabolic Profiles in Chinese Nonobese PCOS Patients.

Phase 4 Unknown

60 enrolled

Polycystic Ovary Syndrome

NCT00099021 2022-02-11

Pioglitazone Hydrochloride in Preventing Head and Neck Cancer in Patients With Oral Leukoplakia

21 enrolled 6 charts

Head & Neck

Head and Neck Neoplasms, Leukoplakia, Oral

NCT04867252 2021-09-13

Effects of Combined Resveratrol and Myo-inositol on Altered Metabolic, Endocrine Parameters and Perceived Stress in Patients With Polycystic Ovarian Syndrome

88 enrolled

Polycystic Ovary Syndrome

NCT04883125 2021-05-12

Value of Using Pioglitazone in Chronic Myeloid Leukemia Treatment

90 enrolled

Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Chronic-Phase

NCT01838317 2021-03-01

A Phase II Study of Pioglitazone for Patients With Cancer of the Pancreas

Other hematologic neoplasm

14 enrolled 8 charts

Gastrointestinal

Pancreatic Neoplasms

NCT02767063 2020-08-07

ACTIW

Phase 1/2 Unknown

100 enrolled

Leukemia, Myeloid, Chronic-Phase

NCT02347813 2020-06-23

Preventing Squamous Cell Skin Cancer

Phase EARLY_PHASE1 Completed

12 enrolled 10 charts

Dermatologic

Carotid Intimal Medial Thickness 1, Carcinoma, Squamous Cell, Skin Neoplasms

NCT03117517 2020-03-02

Treatment With Metformin and Combination of Metformin and Pioglitazone in Polycystic Ovarian Syndrome

106 enrolled 7 charts

Polycystic Ovary Syndrome

NCT02689843 2019-11-12

AntiPCO

Phase EARLY_PHASE1 Completed

90 enrolled

Inflammation, Polycystic Ovary Syndrome

NCT00694759 2019-09-09

Cortisol Regulation in Polycystic Ovary Syndrome (PCOS)

Phase NA Completed

37 enrolled

Insulin Resistance, Polycystic Ovary Syndrome

NCT02730195 2019-01-09

Pioglitazone and Tyrosine Kinase Inhibitor in Treating Patients With Relapsed Chronic Myeloid Leukemia

9 enrolled 8 charts

Phase EARLY_PHASE1 Terminated

Leukemia, Myelogenous, Chronic, BCR-ABL Positive

NCT00867126 2018-11-26

Pioglitazone as Second-Line in Patients With Metastatic Pancreatic Cancer After Treatment With Gemcitabine

6 enrolled

Gastrointestinal

Pancreatic Neoplasms

NCT01151670 2018-08-01

Pioglitazone Hydrochloride in Preventing Radiation-Induced Cognitive Dysfunction in Treating Patients With Brain Tumors

Phase 1 Completed

18 enrolled

CNS

Astrocytoma, Brain Neoplasms, Glioblastoma, Memory Disorders, Meningioma, Cognitive Dysfunction

NCT02889003 2018-03-22

PIO2STOP

Phase 2 Unknown

26 enrolled

Leukemia, Myelogenous, Chronic, BCR-ABL Positive

NCT02852083 2018-01-18

ModuLung

Phase 2 Unknown

86 enrolled

Carcinoma, Non-Small-Cell Lung

NCT01342770 2017-12-05

Pioglitazone Hydrochloride in Treating Patients With Stage IA-IIIA Non-small Cell Lung Cancer

6 enrolled 12 charts

Carcinoma, Non-Small-Cell Lung

NCT01655719 2017-10-26

Pioglitazone in Thyroid Cancers

1 enrolled 6 charts

EndocrineHead & Neck

Thyroid Cancers That Contain the PAX8-PPARgamma Fusion Gene

NCT01911728 2017-06-26

Drug-drug Interaction Study With MDV3100 and a Cocktail of Substrates

Phase 1 Completed

14 enrolled

Pharmacokinetics of MDV3100

NCT00427999 2016-11-21

INV342

67 enrolled 6 charts

Prostatic Neoplasms

NCT00868140 2016-06-10

PCOS

Phase NA Terminated

51 enrolled 10 charts

Polycystic Ovary Syndrome

NCT00951379 2016-04-06

Pioglitazone for Oral Premalignant Lesions

52 enrolled 23 charts

Head & Neck

Leukoplakia, Oral

NCT02687425 2016-02-22

SESPI

Phase 2 Unknown

20 enrolled

Leukemia, Myelogenous, Chronic, BCR-ABL Positive

NCT01223196 2016-01-11

PIO-TACE

Phase 4 Completed

60 enrolled 8 charts

Diabetes Mellitus, Type 2, Insulin Resistance

NCT00923949 2015-09-30

Pioglitazone to Treat Adults Undergoing Surgery for Non-small Cell Lung Cancer

1 enrolled 7 charts