Clinical Trials

160 enrolled

Brain Neoplasms, Craniopharyngioma

NCT04671667 2026-04-17

Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma

188 enrolled

Head & Neck

Squamous Cell Carcinoma of Head and Neck

NCT01512589 2026-04-15

Proton Beam Therapy (PBT) Versus Intensity-Modulated Radiation Therapy (IMRT) Trial

147 enrolled

Adenocarcinoma, Carcinoma, Squamous Cell, Esophageal Neoplasms

NCT03323463 2026-04-13

Major De-escalation to 30 Gy for Select Human Papillomavirus Associated Oropharyngeal Carcinoma

316 enrolled

Head & Neck

Squamous Cell Carcinoma of Head and Neck

NCT03164460 2026-03-20

Stereotactic Body Radiation Therapy or Intensity Modulated Radiation/Proton Therapy in Treating Patients With Recurrent Head and Neck Cancer

Phase 2 Suspended

68 enrolled

Head & Neck

Recurrent Head and Neck Carcinoma

NCT04190446 2026-03-16

A Study to Evaluate Hypofractionated Proton Therapy or IMRT for Recurrent, Oligometastatic Prostate Cancer

84 enrolled

Prostatic Neoplasms

NCT00496522 2026-03-09

Proton Beam Therapy for Chondrosarcoma

15 enrolled

Chondrosarcoma

NCT02125786 2026-02-24

A Trial of Surgery and Fractionated Re-Irradiation for Recurrent Ependymoma

68 enrolled 11 charts

Ependymoma

NCT01946529 2026-02-23

Therapeutic Trial for Patients With Ewing Sarcoma Family of Tumor and Desmoplastic Small Round Cell Tumors

24 enrolled 11 charts

Neuroectodermal Tumors, Primitive, Peripheral, Desmoplastic Small Round Cell Tumor

NCT05320406 2026-02-12

REVELUTION

94 enrolled 13 charts

Prostatic Neoplasms

NCT03624660 2026-02-10

PR11

100 enrolled

Prostatic Neoplasms

NCT04968990 2026-01-23

Treatment of Newly Diagnosed Patient's With Wilm's Tumor Requiring Abdominal Radiation Delivered With Proton Beam Irradiation

260 enrolled

Wilms Tumor

NCT02179086 2026-01-14

Dose-Escalated Photon IMRT or Proton Beam Radiation Therapy Versus Standard-Dose Radiation Therapy and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma

606 enrolled

Glioblastoma

NCT01245712 2025-12-17

Radiation Therapy in Treating Patients With Stage 0-II Breast Cancer

200 enrolled

Breast

Breast Carcinoma In Situ, Breast Neoplasms, Carcinoma, Intraductal, Noninfiltrating

NCT01871766 2025-12-17

Risk-Adapted Focal Proton Beam Radiation and/or Surgery in Patients With Low, Intermediate and High Risk Rhabdomyosarcoma Receiving Standard or Intensified Chemotherapy

115 enrolled

Rhabdomyosarcoma

NCT00496119 2025-12-16

Proton Beam Therapy for Chordoma Patients

19 enrolled

Chordoma

NCT03132532 2025-11-25

Platinum Doublet Chemotherapy and Proton Beam Radiation Therapy in Treating Patients With Stage II-III Non-small Cell Lung Cancer That Cannot Be Removed by Surgery

20 enrolled 20 charts

Thoracic

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT06008730 2025-11-10

Proton Beam Radiation Therapy After Treatment for Resected N2 Non-Small Cell Lung Cancer

20 enrolled

Resectable Lung Non-Small Cell Carcinoma

NCT01419067 2025-10-20

A Phase II Trial of Limited Surgery and Proton Therapy for Craniopharyngioma or Observation After Radical Resection

112 enrolled

Craniopharyngioma

NCT02598349 2025-09-09

Proton Radiation for Unresectable, Borderline Resectable, or Medically Inoperable Carcinoma of the Pancreas

60 enrolled

Pancreatic Neoplasms

NCT03180502 2025-07-11

Proton Beam or Intensity-Modulated Radiation Therapy in Preserving Brain Function in Patients With IDH Mutant Grade II or III Glioma

120 enrolled

Astrocytoma, Glioma, Oligodendroglioma

NCT03778294 2025-07-03

18F-DOPA-PET/MRI Scan in Imaging Elderly Patients With Newly Diagnosed Grade IV Malignant Glioma or Glioblastoma During Planning for a Short Course of Proton Beam Radiation Therapy

43 enrolled 19 charts

Glioblastoma, Glioma

NCT03018418 2024-09-19

Proton Therapy in Reducing Toxicity in Anal Cancer

14 enrolled 14 charts

Anus Neoplasms

NCT06462378 2024-06-17

Proton Therapy for Locally Advanced Cervical Cancer

55 enrolled

Gynecologic

Uterine Cervical Neoplasms, Radiation Injuries

NCT02073968 2024-01-25

PAINT

35 enrolled 13 charts

CNSThoracic

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung

NCT00895622 2023-09-08

Observation or Radiation Therapy in Treating Patients With Grade I, Grade II, or Grade III Meningioma

244 enrolled 15 charts

Brain Neoplasms, Meningioma, Central Nervous System Neoplasms

NCT01730950 2022-12-29

Bevacizumab With or Without Radiation Therapy in Treating Patients With Recurrent Glioblastoma

182 enrolled 19 charts

CNSSarcoma

Brain Neoplasms, Glioblastoma, Gliosarcoma

NCT01821729 2020-09-25

Proton w/FOLFIRINOX-Losartan for Pancreatic Cancer

Phase 2 Unknown

50 enrolled 11 charts

Pancreatic Neoplasms

NCT00915005 2020-05-26

Trial of Image-Guided Adaptive Conformal Photon vs Proton Therapy, With Concurrent Chemotherapy, for Locally Advanced Non-Small Cell Lung Carcinoma: Treatment Related Pneumonitis and Locoregional Recurrence

275 enrolled 16 charts

Thoracic

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT01019278 2020-04-03

Proton Beam Radiation Therapy and Cisplatin in Treating Patients With Stage IB, Stage II, Stage III, or Stage IVA Cervical Cancer and Positive Lymph Nodes

Phase 2 Withdrawn

Gynecologic

Uterine Cervical Neoplasms

NCT03234842 2018-12-21

ES01

Phase 2 Withdrawn

Esophageal Neoplasms

NCT01553019 2017-09-06

PC03

2 enrolled

Pancreatic Neoplasms

NCT00585962 2017-09-05

Proton Beam Radiation Therapy for Early Stage Adenocarcinoma of the Prostate

57 enrolled

Prostatic Neoplasms

NCT00881595 2017-02-10

SA02

Phase 2 Withdrawn