Clinical Trials

160 enrolled

Brain Neoplasms, Craniopharyngioma

NCT01512589 2026-04-15

Proton Beam Therapy (PBT) Versus Intensity-Modulated Radiation Therapy (IMRT) Trial

147 enrolled

Gastrointestinal

Adenocarcinoma, Carcinoma, Squamous Cell, Esophageal Neoplasms

NCT03323463 2026-04-13

Major De-escalation to 30 Gy for Select Human Papillomavirus Associated Oropharyngeal Carcinoma

316 enrolled

Head & Neck

Squamous Cell Carcinoma of Head and Neck

NCT03482791 2026-04-02

Proton Beam Therapy in the Treatment of Esophageal Cancer

22 enrolled 29 charts

Gastrointestinal

Esophageal Neoplasms

NCT03281889 2026-03-19

Proton Craniospinal Irradiation With Bone Sparing to Decrease Growth Decrement From Radiation

20 enrolled

Brain Neoplasms

NCT04190446 2026-03-16

A Study to Evaluate Hypofractionated Proton Therapy or IMRT for Recurrent, Oligometastatic Prostate Cancer

84 enrolled

Prostatic Neoplasms

NCT07450560 2026-03-10

Research on Real-time Proton Therapy Guidance Through Monitoring Proton Range Using All-digital PET

Active not recruiting

30 enrolled

Other solid neoplasm

Solid Tumor

NCT00496522 2026-03-09

Proton Beam Therapy for Chondrosarcoma

Phase 1/2 Active not recruiting

15 enrolled

Sarcoma

Chondrosarcoma

NCT01629498 2026-03-09

Image-Guided, Intensity-Modulated Photon or Proton Beam Radiation Therapy in Treating Patients With Stage II-IIIB Non-small Cell Lung Cancer

146 enrolled

Thoracic

Carcinoma, Non-Small-Cell Lung

NCT01893307 2026-02-24

Intensity-Modulated Proton Beam Therapy or Intensity-Modulated Photon Therapy in Treating Patients With Stage III-IVB Oropharyngeal Cancer

Phase 3 Active not recruiting

440 enrolled

Head & Neck

Squamous Cell Carcinoma of Head and Neck

NCT02125786 2026-02-24

A Trial of Surgery and Fractionated Re-Irradiation for Recurrent Ependymoma

68 enrolled 11 charts

Ependymoma

NCT01946529 2026-02-23

Therapeutic Trial for Patients With Ewing Sarcoma Family of Tumor and Desmoplastic Small Round Cell Tumors

24 enrolled 11 charts

Neuroectodermal Tumors, Primitive, Peripheral, Desmoplastic Small Round Cell Tumor

NCT05320406 2026-02-12

REVELUTION

94 enrolled 13 charts

Prostatic Neoplasms

NCT01049230 2026-02-11

Proton Beam Radiation Therapy for Central Nervous System (CNS) Germ Cell Tumors

45 enrolled

Neoplasms, Germ Cell and Embryonal

NCT03624660 2026-02-10

PR11

100 enrolled

Prostatic Neoplasms

NCT01617161 2026-01-22

PARTIQoL

454 enrolled

Phase 3 Active not recruiting

Prostatic Neoplasms

NCT04443413 2026-01-16

Phase III Study of 5tx vs 15tx of RT (X-rays or Protons) Including RNI in Breast Cancer Patients

146 enrolled

Breast

Anatomic Stage I Breast Cancer AJCC v8

NCT02179086 2026-01-14

Dose-Escalated Photon IMRT or Proton Beam Radiation Therapy Versus Standard-Dose Radiation Therapy and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma

606 enrolled

Phase 1/2 Active not recruiting

Glioblastoma

NCT01950351 2025-12-22

Hypofractionated Proton Beam Therapy for Localized Prostate Cancer

241 enrolled

Stage I Prostate Adenocarcinoma AJCC v7

NCT01245712 2025-12-17

Radiation Therapy in Treating Patients With Stage 0-II Breast Cancer

200 enrolled

Breast

Breast Carcinoma In Situ, Breast Neoplasms, Carcinoma, Intraductal, Noninfiltrating

NCT01871766 2025-12-17

Risk-Adapted Focal Proton Beam Radiation and/or Surgery in Patients With Low, Intermediate and High Risk Rhabdomyosarcoma Receiving Standard or Intensified Chemotherapy

115 enrolled

Sarcoma

Rhabdomyosarcoma

NCT00496119 2025-12-16

Proton Beam Therapy for Chordoma Patients

19 enrolled

Sarcoma

Chordoma

NCT01358058 2025-12-10

Proton Radiation Therapy for Gliomas

63 enrolled

Brain Neoplasms, Glioma

NCT01419067 2025-10-20

A Phase II Trial of Limited Surgery and Proton Therapy for Craniopharyngioma or Observation After Radical Resection

112 enrolled

Phase 1/2 Active not recruiting

Craniopharyngioma

NCT02444741 2025-10-09

Pembrolizumab and Stereotactic Body Radiation Therapy or Non-Stereotactic Wide-Field Radiation Therapy in Treating Patients With Non-small Cell Lung Cancer

126 enrolled

Thoracic

Carcinoma, Non-Small-Cell Lung

NCT01352429 2025-07-17

Mild Hypofractionation With Proton Therapy or IMRT for Intermediate-Risk Prostate Cancer

Active not recruiting

303 enrolled

Prostate Adenocarcinoma

NCT03180502 2025-07-11

Proton Beam or Intensity-Modulated Radiation Therapy in Preserving Brain Function in Patients With IDH Mutant Grade II or III Glioma

120 enrolled

Astrocytoma, Glioma, Oligodendroglioma

NCT03018418 2024-09-19

Proton Therapy in Reducing Toxicity in Anal Cancer