Clinical Trials

46 enrolled

Breast

Breast Neoplasms

NCT05616650 2026-04-16

Focal Therapy With Stereotactic Body Radiation Therapy (SBRT) for Patients With a Single Prostate Tumor

42 enrolled

Prostatic Neoplasms

NCT04693377 2026-04-15

Cryoablation Combined With Stereotactic Body Radiation Therapy for the Treatment of Painful Bone Metastases, the CROME Trial

DermatologicGastrointestinalGenitourinaryHead & NeckSarcoma

40 enrolled

Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Melanoma, Neoplasm Metastasis, Prostatic Neoplasms, Sarcoma, Thyroid Neoplasms, Colorectal Neoplasms

NCT06649058 2026-04-15

EXCLAIM: Exploring Combined Local and Systemic Approaches In Brain Metastasis: a Multi-cohort Randomized Phase II Study Evaluating Initial Response to Systemic Therapy and Subsequent Integration of Stereotactic Radiosurgery in Patients With Low-risk Brain Metastases and Central Nervous System-active

316 enrolled

Brain Neoplasms

NCT07126158 2026-04-15

Stereotactic Body Radiotherapy Plus FAK and RAF/MEK Inhibition in Advanced Pancreatic Adenocarcinoma

36 enrolled

Pancreatic Neoplasms

NCT07530172 2026-04-15

REVERT

146 enrolled

Heptocellular Cancer

NCT03550391 2026-04-14

Stereotactic Radiosurgery Compared With Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) Plus Memantine for 5 or More Brain Metastases

206 enrolled

Brain Neoplasms

NCT06641791 2026-04-14

Palliative Steroeotactic Body Radiotherapy vs Palliative Standard Radiotherapy in Patients With Advanced Head and Neck Cancer

196 enrolled

Head & Neck

Head and Neck Neoplasms

NCT05222620 2026-04-13

SRS Compared With FSRS for Treatment of Intact Metastatic Brain Disease, FRACTIONATE Trial

90 enrolled

Brain Neoplasms, Neoplasm Metastasis

NCT06741085 2026-04-13

A Study of Stereotactic Radiosurgery (SRS) and Standard Treatment in People With Lung Cancer That Has Spread to the Brain

56 enrolled

Non Small Cell Lung Cancer Metastatic

NCT05178472 2026-04-09

Vertebroplasty With Radiation Therapy for Spine Metastatic Cancer Patients With Indeterminate Lesion (SINS Criteria)

Other hematologic neoplasm

200 enrolled

Hematologic Neoplasms

NCT07293468 2026-04-09

BIIRTH

Phase 2/3 Recruiting

106 enrolled

Carcinoma, Hepatocellular

NCT05987644 2026-04-08

DURABLE

Phase 1/2 Recruiting

56 enrolled

CNSThoracic

Brain Neoplasms, Lung Neoplasms

NCT06248606 2026-04-08

Adagrasib + SRS for Patients With Metastatic KRAS G12C-mutated NSCLC With Untreated Brain Metastases

30 enrolled

Carcinoma, Non-Small-Cell Lung

NCT07166406 2026-04-08

Testing Immunotherapy With or Without Stereotactic Body Radiation Therapy in Patients With Advanced Liver Cancer, HELIO-RT Trial

226 enrolled

Carcinoma, Hepatocellular

NCT05361798 2026-04-06

A Phase II Study Evaluating T-Cell Clonality After Stereotactic Body Radiation Therapy Alone and in Combination With the Immunocytokine PDS01ADC in Localized High and Intermediate Risk Prostate Cancer Treated With Androgen Deprivation Therapy

65 enrolled

Prostatic Neoplasms

NCT04423211 2026-04-03

Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging

804 enrolled

Prostatic Neoplasms

NCT04804644 2026-04-03

Testing if High Dose Radiation Only to the Sites of Brain Cancer Compared to Whole Brain Radiation That Avoids the Hippocampus is Better at Preventing Loss of Memory and Thinking Ability

200 enrolled

CNSThoracic

Brain Neoplasms, Lung Neoplasms, Small Cell Lung Carcinoma

NCT05624996 2026-04-03

Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer

474 enrolled

Lung Neoplasms

NCT05946213 2026-04-03

Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer

1,209 enrolled

Prostatic Neoplasms

NCT06500455 2026-04-03

Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain

BreastCNSDermatologicGenitourinaryThoracic

269 enrolled

Brain Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Lung Neoplasms, Melanoma, Neoplasm Metastasis

NCT06325046 2026-03-31

Adaptive Radiation Therapy (ART) Stereotactic Ablative Body Radiotherapy (SABR) for Primary Localized Prostate Cancer

144 enrolled

Prostatic Neoplasms

NCT02016248 2026-03-30

SBRT Boost for Unfavorable Prostate Cancer'

150 enrolled

Prostatic Neoplasms

NCT04235777 2026-03-27

Bintrafusp Alfa (M7824) and PDS01ADC Alone and in Combination With Stereotactic Body Radiation Therapy (SBRT) in Adults With Metastatic Non-Prostate Genitourinary Malignancies

100 enrolled

Urinary Bladder Neoplasms, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Urogenital Neoplasms

NCT06391242 2026-03-27

Stereotactic Body Radiotherapy vs Conventional Palliative Radiotherapy for Painful Non-Spine Bone Metastases

230 enrolled

Tumor-Agnostic

Neoplasm Metastasis

NCT05702749 2026-03-24

VS PREHAB

36 enrolled

Neuroma, Acoustic

NCT07426055 2026-03-23

PRO-BOOST-LC

Phase 2/3 Recruiting

1,200 enrolled

Adenocarcinoma, Prostatic Neoplasms

NCT06738160 2026-03-20

The Efficacy and Safety of Narlumosbart in Combination With Stereotactic Body Radiation Therapy to Improve the Efficacy of First-line Chemotherapy Combined With Immunotherapy in Patients With Bone Metastases From Advanced Non-small Cell Lung Cancer

27 enrolled

NSCLC

NCT07189598 2026-03-19

ORION

390 enrolled

Prostatic Neoplasms

NCT06211335 2026-03-12

Losartan, Pembrolizumab and Stereotactic Body Radiation Therapy for the Treatment of Patients With Locally Recurrent, Refractory or Oligometastatic Head and Neck Squamous Cell Carcinoma

24 enrolled

Head & Neck

Squamous Cell Carcinoma of Head and Neck

NCT06523634 2026-03-12

STEREOBED

284 enrolled

Prostatic Neoplasms

NCT06369246 2026-03-09

PRORAD-5 PROstate RADiation in 5 Fractions: Phase II Five Fraction Radiotherapy for Patients With Advanced Prostate Cancer.

70 enrolled

Advanced Prostate Cancer

NCT01803542 2026-03-06

SBRT Lung

200 enrolled

Carcinoma, Non-Small-Cell Lung

NCT07112170 2026-03-05

CURB-Melanoma

52 enrolled

Dermatologic

Melanoma

NCT07451795 2026-03-05

SHARP

66 enrolled

Prostatic Neoplasms

NCT05068232 2026-03-04

Durvalumab and Ablative Radiation in Small Cell Lung Cancer (DARES)

49 enrolled

Lung Neoplasms, Small Cell Lung Carcinoma

NCT05789589 2026-03-04

ADORATION

Phase 1/2 Recruiting

46 enrolled

Brain Neoplasms, Neoplasm Metastasis, Neoplasms

NCT06823375 2026-03-04

SBRT With Immunotherapy and Atezo-Bev in HCC With Major Portal Vein Thrombosis

40 enrolled

HCC

NCT06218420 2026-03-03

TRANSRAD-01

139 enrolled

Carcinoma, Hepatocellular

NCT06492954 2026-03-02

AflacST2301

12 enrolled

Sarcoma

Osteosarcoma

NCT07150546 2026-03-02

Combination External Radiation and PRRT for Large GI Neuroendocrine Tumors.

EndocrineGastrointestinalNET

15 enrolled

Gastro-enteropancreatic neuroendocrine tumor

NCT06835725 2026-02-27

ADAPT-25

100 enrolled

Prostate CA

NCT07429422 2026-02-24

SBRT Technique Implementation for Spinal Metastases Irradiation

100 enrolled

Spinal Cord Neoplasms

NCT05488522 2026-02-20

SBRT With Atezo/Bev for HCC

18 enrolled

Carcinoma, Hepatocellular

NCT02984761 2026-02-19

Bronchial Neoplasms, Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, Lung Diseases, Lung Neoplasms, Neoplasms, Neoplasms by Site, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Thoracic Neoplasms

NCT05674396 2026-02-19

3-5 FrAction Stereotactic Body Radiation Therapy for Palliation of Head and Neck Squamous Cell Carcinoma: the FAST Phase II Randomized Trial

108 enrolled

Head & Neck

Squamous Cell Carcinoma of Head and Neck

NCT04983095 2026-02-17

METRO

118 enrolled

Prostate Cancer Metastatic

NCT05419076 2026-02-11

A Study of Stereotactic Radiosurgery (SRS) for People With Lung Cancer That Has Spread to the Brain

62 enrolled

CNSThoracic

Brain Neoplasms, Lung Neoplasms, Small Cell Lung Carcinoma

NCT03073278 2026-02-06

Focal Radiotherapy for Previously Treated Prostate Cancer Patients

36 enrolled

Locally Recurrent Prostate Cancer

NCT04923542 2026-02-06

Stereotactic Radiation & Abemaciclib in the Management of HR+/HER2- Breast Cancer Brain Metastases

Phase 1/2 Recruiting

31 enrolled