Clinical Trials

36 enrolled

Fibrosis, Carcinoma, Hepatocellular, Cholangiocarcinoma

NCT06760481 2026-04-15

Phase I/Ib Trial of TIraGolumab, AtEzolizumab, and RadScopal Radiation in Patients With Advanced Solid Malignancies (TIGER)

7 enrolled

Advanced Solid Malignancies

NCT03528642 2026-04-13

Telaglenastat With Radiation Therapy and Temozolomide in Treating Patients With IDH-Mutated Diffuse Astrocytoma or Anaplastic Astrocytoma

40 enrolled

CNSLymphoid

Astrocytoma, Lymphoma, Follicular

NCT04052555 2026-04-13

Testing the Addition of an Anti-cancer Drug, Berzosertib, to the Usual Treatment (Radiation Therapy) for Chemotherapy-Resistant Triple-Negative and Estrogen and/or Progesterone Receptor Positive, HER2 Negative Breast Cancer

42 enrolled

Breast

Breast Neoplasms, Triple Negative Breast Neoplasms

NCT05172245 2026-04-13

Testing the Addition of Ipatasertib to Usual Chemotherapy and Radiation for Head and Neck Cancer

46 enrolled

Carcinoma, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Oropharyngeal Neoplasms

NCT06116786 2026-04-13

A Study of JNJ-86974680 in Participants With Advanced Non-small Cell Lung Cancer

126 enrolled

Carcinoma, Non-Small-Cell Lung

NCT02819752 2026-04-09

PEACH

3 enrolled 12 charts

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell

NCT06344130 2026-04-09

Hypofractionation Trial of Re-irradiation in Good Prognosis Recurrent Glioblastoma

28 enrolled

Astrocytoma, Glioblastoma, Glioma

NCT06848465 2026-04-03

LDRT Combined With Immunochemotherapy for Colorectal Cancer With Liver Metastasis

9 enrolled

Colorectal Neoplasms

NCT06110195 2026-03-31

Study of Xevinapant With Radiation and Chemotherapy for Patients With Head and Neck Cancer

42 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT06934889 2026-03-30

Study of ABBV-637 or ABBV-155 With ERAS-801 for People With Glioblastoma

60 enrolled

CNSSarcoma

Glioblastoma, Gliosarcoma

NCT03605550 2026-03-27

A Phase 1b Study of PTC596 in Children With Newly Diagnosed Diffuse Intrinsic Pontine Glioma and High Grade Glioma

64 enrolled

Diffuse Intrinsic Pontine Glioma, Glioma

NCT03739411 2026-03-27

Hyperpolarized Imaging in Diagnosing Participants With Glioma

140 enrolled

Glioma

NCT01783587 2026-03-25

Safety Study of Afatinib and Postoperative Radiation Therapy to Treat Head and Neck Cancer

29 enrolled

Phase 1 Not yet recruiting

Squamous Cell Carcinoma of Head and Neck

NCT07478679 2026-03-23

Radiation to Treat Joint Damage Caused by Cancer Immunotherapy

20 enrolled

Arthritis, Joint Diseases

NCT04484909 2026-03-20

NBTXR3 Activated by Radiation Therapy for the Treatment of Locally Advanced or Borderline-Resectable Pancreatic Cancer

Phase 1 Suspended

Pancreatic Neoplasms

NCT04732065 2026-03-17

PNOC023

208 enrolled

Ependymoma, Glioblastoma, Central Nervous System Neoplasms

NCT05813327 2026-03-17

Neoadjuvant ADI-PEG 20 + Ifosfamide + Radiotherapy in Soft Tissue Sarcoma

6 enrolled

Sarcoma, Ichthyosis, X-Linked

NCT05109728 2026-03-16

A Dose Finding Study of [177Lu]Lu-DOTA-TATE in Newly Diagnosed Glioblastoma in Combination With Standard of Care and in Recurrent Glioblastoma as a Single Agent.

65 enrolled

Glioblastoma

NCT02287428 2026-03-12

Personalized NeoAntigen Cancer Vaccine w RT Plus Pembrolizumab for Patients With Newly Diagnosed GBM

56 enrolled

Glioblastoma

NCT06894979 2026-03-12

Testing the Addition of an Anti-Cancer Drug, AZD1390, During Radiation Therapy for Newly Diagnosed High Grade Glioma, Diffuse Midline Glioma, or Diffuse Intrinsic Pontine Glioma

54 enrolled

Astrocytoma

NCT03968406 2026-03-11

Talazoparib and Radiation Therapy in Treating Patients With Locally Recurrent Gynecologic Cancers

Gynecologic

Uterine Cervical Neoplasms, Fallopian Tube Neoplasms, Ovarian Neoplasms, Vaginal Neoplasms, Endometrial Neoplasms

NCT04505267 2026-03-11

NBTXR3 and Radiation Therapy for the Treatment of Inoperable Recurrent Non-small Cell Lung Cancer

34 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT02402920 2026-03-10

Pembrolizumab and Concurrent Chemoradiotherapy or Radiation Therapy in Treating Patients With Small Cell Lung Cancer

83 enrolled 13 charts

EndocrineNET

Neuroendocrine Tumors

NCT04420975 2026-03-10

Nivolumab and BO-112 Before Surgery for the Treatment of Resectable Soft Tissue Sarcoma

14 enrolled

Phase 1 Not yet recruiting

Leiomyosarcoma, Sarcoma, Sarcoma, Synovial, Dermatofibrosarcoma, Neurofibrosarcoma, Histiocytoma, Malignant Fibrous

NCT07457307 2026-03-09

INSIGHT MRL

20 enrolled

Glioma

NCT02959463 2026-03-06

Pembrolizumab After Radiation Therapy in Treating Patients With Pleural Malignant Mesothelioma

Other solid neoplasmThoracic

24 enrolled 11 charts

Mesothelioma, Malignant

NCT04013542 2026-03-05

Ipilimumab and Nivolumab in Combination With Radiation Therapy in Treating Patients With Stage 2-3 Non-small Lung Cancer

21 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT04170946 2026-03-05

Talazoparib

Lung Neoplasms, Small Cell Lung Carcinoma

NCT04522336 2026-03-05

Pembrolizumab and Chemoradiotherapy for the Treatment of Unresectable Gastroesophageal Cancer

16 enrolled

Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8

NCT06459869 2026-02-17

FORTRESS

30 enrolled

Locally Advanced Rectal Cancer (LARC)

NCT06678269 2026-02-12

A Study of Abemaciclib and Radiation Therapy in People With Metastatic Breast Cancer

28 enrolled

Breast

Breast Neoplasms

NCT07222735 2026-02-09

Hypofractionated Radiation in Combination With B7-H3-CAR T Cells for Pediatric Patients With Relapsed/Refractory Sarcomas

42 enrolled

Sarcoma, Sarcoma, Ewing

NCT05443971 2026-02-06

Durvalumab and Grid Therapy for Non-small Cell Lung Cancer in Progression During or After Treatment With PACIFIC Regimen

4 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT04754321 2026-02-02

Combining Immunotherapy Salvage Surgery & IORT Tx Persistent/Recurrent Head & Neck Cancer

45 enrolled

Squamous Cell Carcinoma of Head and Neck

NCT04391049 2026-01-30

Testing the Addition of the Anti-cancer Viral Therapy Telomelysin™ to Chemoradiation for Patients With Advanced Esophageal Cancer and Are Not Candidates for Surgery

16 enrolled 15 charts

Carcinoma, Squamous Cell, Neoplasms, Squamous Cell

NCT05116254 2026-01-23

SADDRIN-1

12 enrolled

NCT04523818 2026-01-14

Short-Course Chemoradiotherapy Followed by Chemotherapy for the Treatment of Resectable Gastric Adenocarcinoma

25 enrolled

Clinical Stage I Gastric Cancer AJCC v8

NCT05236036 2026-01-14

Mycophenolate Mofetil in Combination With Standard of Care for the Treatment of Glioblastoma

60 enrolled

Astrocytoma, Glioblastoma

NCT05083754 2026-01-09

Carmustine Wafer in Combination With Retifanlimab and Radiation With/Without Temozolomide in Subjects With Glioblastoma

50 enrolled

Glioblastoma

NCT04616248 2026-01-07

In Situ Immunomodulation With CDX-301, Radiation Therapy, CDX-1140 and Poly-ICLC in Patients w/ Unresectable and Metastatic Solid Tumors

BreastDermatologicSarcoma

14 enrolled

Bone Neoplasms, Breast Neoplasms, Carcinoma, Basal Cell, Melanoma, Sarcoma, Osteosarcoma, Carcinoma, Merkel Cell

NCT02560636 2026-01-06

PLUMMB

34 enrolled

Tumor-Agnostic

Neoplasm Metastasis

NCT06494189 2025-12-29

Low-dose Radiotherapy Plus Tislelizumab in Combination With Afatinib for Neoadjuvant Treatment of Surgically Resectable Head and Neck Squamous Carcinoma

9 enrolled

Head and Neck Neoplasms

NCT03423628 2025-12-22

A Study to Assess the Safety and Tolerability of AZD1390 Given With Radiation Therapy in Patients With Brain Cancer

180 enrolled

Brain Neoplasms, Glioblastoma, Inhibition, Psychological, Meningeal Neoplasms, Hereditary Sensory and Autonomic Neuropathies

NCT01407198 2025-12-19

Nilotinib With Radiation for High Risk Chordoma

23 enrolled

Chordoma

NCT01746238 2025-12-19

Bevacizumab/Doxorubicin/Radiation for Sarcoma

14 enrolled

NCT04550104 2025-12-19

CONCORDE

200 enrolled

Carcinoma, Non-Small-Cell Lung

NCT06349837 2025-12-17

Safety and Tolerability of LDRT Plus Concurrent Partial SBRT and Tislelizumab in Patients With Bulky Tumors

Other solid neoplasm

Solid Tumor

NCT03542175 2025-12-08

A Study of Rucaparib Administered With Radiation in Patients With Triple Negative Breast Cancer With an Incomplete Response Following Chemotherapy

31 enrolled 12 charts

Breast

Breast Neoplasms, Triple Negative Breast Neoplasms

NCT07269899 2025-12-08

Reboot-107