Clinical Trials

Phase 3 Active not recruiting

Glioblastoma

NCT04210115 2026-05-13

KEYNOTE 975

703 enrolled

Adenocarcinoma Of Esophagus, Parkinson Disease 4, Autosomal Dominant Lewy Body, Esophageal Squamous Cell Carcinoma

NCT04892173 2026-05-11

JNJ-90301900 (NBTXR3) Activated by Radiotherapy With or Without Cetuximab in LA-HNSCC

Phase 3 Recruiting

500 enrolled

Head & Neck

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell

NCT06667908 2026-05-11

CONVERGE

Phase 2 Recruiting

130 enrolled

Phase 3 Active not recruiting

Carcinoma, Non-Small-Cell Lung

NCT04557059 2026-05-08

PRIMORDIUM

692 enrolled

Genitourinary

Prostatic Neoplasms

NCT06116786 2026-05-08

A Study of JNJ-86974680 in Participants With Advanced Non-small Cell Lung Cancer

126 enrolled

Phase 1/2 Active not recruiting

Carcinoma, Non-Small-Cell Lung

NCT03491683 2026-05-04

INO-5401 and INO-9012 Delivered by Electroporation (EP) in Combination With Cemiplimab (REGN2810) in Newly-Diagnosed Glioblastoma (GBM)

52 enrolled

Phase 2 Active not recruiting

Glioblastoma

NCT05765812 2026-04-28

A Study of Debio 0123 in Combination With Temozolomide in Adult Participants With Recurrent or Progressive Glioblastoma and of Debio 0123 in Combination With Temozolomide and Radiotherapy in Adult Participants With Newly Diagnosed Glioblastoma

Phase 1/2 Recruiting

116 enrolled

CNSLymphoid

Astrocytoma, Glioblastoma, Lymphoma, Follicular

NCT05009069 2026-04-21

A Study of Atezolizumab With or Without Tiragolumab Following Neoadjuvant Chemoradiotherapy in Participants With Locally Advanced Rectal Cancer

58 enrolled

Rectal Neoplasms

NCT03957590 2026-04-13

A Study to Investigate Tislelizumab (BGB-A317) Versus Placebo in Combination With Concurrent Chemoradiotherapy in Participants With Localized Esophageal Squamous Cell Carcinoma

370 enrolled 17 charts

Esophageal Squamous Cell Carcinoma

NCT05124912 2026-02-20

REMASTer: REcurrent Brain Metastases After SRS Trial

Phase NA Recruiting

261 enrolled

Phase 2 Active not recruiting

Brain Neoplasms, Neoplasm Metastasis, Recurrence

NCT03407144 2026-02-19

MK-3475-667

340 enrolled

Lymphoid

Hodgkin Disease

NCT05491317 2026-02-19

A Safety and Antitumor Activity Trial of Immunoradiotherapy Combinations as a Treatment Option for Subjects With Metastatic Solid Tumors

Phase 1/2 Terminated

13 enrolled

Non-CNS Tumor

NCT06459869 2026-02-17

FORTRESS

30 enrolled

Locally Advanced Rectal Cancer (LARC)

NCT05415215 2026-02-10

ProHer

346 enrolled 20 charts

Breast

Breast Neoplasms, Patient Preference, Inflammatory Breast Neoplasms

NCT03040999 2026-02-04

KEYNOTE-412

804 enrolled 20 charts

Head & Neck

Parkinson Disease 4, Autosomal Dominant Lewy Body, Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT04504942 2026-01-23

Basket Study of Leronlimab (PRO 140) in Patients With CCR5+ Locally Advanced or Metastatic Solid Tumors

16 enrolled 16 charts

Other solid neoplasm

Solid Tumor, Adult

NCT03423628 2025-12-22

A Study to Assess the Safety and Tolerability of AZD1390 Given With Radiation Therapy in Patients With Brain Cancer

180 enrolled

Phase 1/2 Not yet recruiting

Brain Neoplasms, Glioblastoma, Inhibition, Psychological, Meningeal Neoplasms, Hereditary Sensory and Autonomic Neuropathies

NCT04373785 2025-10-21

NG101m Adjuvant Therapy in Glioblastoma Patients

52 enrolled

Phase 2 Active not recruiting

Glioblastoma

NCT07192588 2025-09-25

GuARD

273 enrolled

Breast

Breast Neoplasms, Radiodermatitis

NCT03444714 2025-09-15

Phase I Study of RiMO-301 With Radiation in Advanced Tumors

32 enrolled

Advanced Tumors

NCT01107522 2025-09-09

Safety and Tolerability of Carboxyamidotriazole Orotate (CTO) in Solid Tumors or With Temodar® in Glioblastoma or Other Recurrent Malignant Gliomas or in Combination With Temodar® and Radiation Therapy for Patients With Newly Diagnosed Glioblastoma and Malignant Gliomas

Phase 1 Unknown

100 enrolled

Phase 3 Active not recruiting

Glioblastoma, Glioma

NCT03725059 2025-07-11

KEYNOTE-756

1,240 enrolled

Breast

Breast Neoplasms

NCT04121455 2025-06-25

GLORIA

Phase 1/2 Active not recruiting

117 enrolled

Brain Neoplasms, Glioblastoma

NCT02667587 2025-06-18

CheckMate548

716 enrolled 15 charts

Brain Neoplasms

NCT02655601 2025-06-08

BMX-HGG

177 enrolled 34 charts

Phase 1 Active not recruiting

Astrocytoma, Glioblastoma, Glioma

NCT05704985 2025-05-29

Evaluating Safety and Biomarkers Using DK210 (EGFR) for Locally Advanced or Metastatic EGFR+ Tumors

39 enrolled

DermatologicGastrointestinalGenitourinaryHead & NeckThoracic

Carcinoma, Non-Small-Cell Lung, Head and Neck Neoplasms, Kidney Neoplasms, Neoplasms, Pancreatic Neoplasms, Skin Neoplasms, Colorectal Neoplasms

NCT03724890 2025-04-10

Study of Avelumab-M3814 Combinations

57 enrolled 56 charts

Tumor-Agnostic

Neoplasms

NCT01249352 2025-03-31

NICE

Phase 2/3 Completed

104 enrolled

Adenocarcinoma, Esophageal Neoplasms

NCT01345084 2025-03-28

NICAP

Phase 3 Withdrawn

Head & Neck

Carcinoma, Head and Neck Neoplasms

NCT06069570 2025-03-05

Safety Study for a Gamma Delta T Cell Product Used With Low Dose Radiotherapy in Patients With Locally Advanced or Metastatic NSCLC or Solid Tumors With Bone Metastases

48 enrolled

Carcinoma, Carcinoma, Non-Small-Cell Lung

NCT03576612 2025-02-14

GMCI

41 enrolled

Glioblastoma, Glioma

NCT05191667 2025-02-13

AN0025 and Chemoradiotherapy Combination in Esophageal Cancer

Phase 1 Suspended

32 enrolled

Esophageal Neoplasms

NCT03515538 2024-11-04

PREVLAR

53 enrolled 15 charts

Head & NeckOther

Head and Neck Neoplasms, Mouth Neoplasms, Stomatitis, Mucositis

NCT04866017 2024-10-31

A Study to Compare Ociperlimab Plus Tislelizumab Versus Durvalumab Following Concurrent Chemoradiotherapy (cCRT) in Participants With Stage III Unresectable Non-Small Cell Lung Cancer

Phase 3 Terminated

63 enrolled 15 charts

Carcinoma, Non-Small-Cell Lung

NCT04324840 2024-07-26

A Study of CC-90010 in Combination With Temozolomide With or Without Radiation Therapy in Participants With Newly Diagnosed Glioblastoma

Phase 1 Terminated

184 enrolled

Metatropic dwarfism, Glioblastoma

NCT03250299 2024-06-24

Microtubule-Targeted Agent BAL101553 and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma

Phase 1 Terminated

26 enrolled 17 charts

Brain Neoplasms, Glioblastoma

NCT02383498 2024-05-20

QUILT-3.011 Phase 2 Yeast-Brachyury Vaccine Chordoma

24 enrolled 8 charts

Sarcoma

Chordoma

NCT03165994 2024-05-02

APX005M With Concurrent Chemoradiation for Resectable Esophageal and Gastroesophageal Junction Cancers

34 enrolled 18 charts

Esophageal Neoplasms

NCT03776071 2024-04-22

A Trial of Enzastaurin Plus Temozolomide During and Following Radiation Therapy in Patients With Newly Diagnosed Glioblastoma With or Without the Novel Genomic Biomarker, DGM1

260 enrolled

Glioblastoma

NCT06368960 2024-04-16

BM201-1001

Phase 1 Unknown

36 enrolled

Other solid neoplasm

Advanced Solid Tumors

NCT02880410 2024-04-12

FLAG

Phase 1 Terminated

3 enrolled

Glioblastoma

NCT00589875 2024-04-03

BrTK02

52 enrolled 10 charts

Astrocytoma, Glioblastoma, Glioma

NCT04551950 2024-03-08

Bintrafusp Alfa Combination Therapy in Participants With Cervical Cancer (INTR@PID 046)

25 enrolled 14 charts

Gynecologic

Uterine Cervical Neoplasms, Camurati-Engelmann Syndrome

NCT02567799 2024-01-25

NSCLC

21 enrolled 32 charts

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT00634231 2023-08-25

A Phase I Study of AdV-tk + Prodrug Therapy in Combination With Radiation Therapy for Pediatric Brain Tumors

8 enrolled

Astrocytoma, Ependymoma, Glioblastoma, Glioma

NCT02617589 2023-03-28

CheckMate 498

560 enrolled 14 charts

Brain Neoplasms

NCT03770689 2023-03-21

Study of Peposertib in Combination With Capecitabine and RT in Rectal Cancer

19 enrolled 21 charts

Locally Advanced Rectal Cancer

NCT02990468 2023-03-15

BMX-HN

29 enrolled 14 charts

Head & NeckOther

Head and Neck Neoplasms, Xerostomia, Mucositis

NCT03867123 2023-02-21

A Study to Evaluate the Safety of LAM561 Added to Standard of Care in Newly-diagnosed Glioblastoma Patients

18 enrolled