Announcements Trials
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Phase

Phase 1 3Phase EARLY_PHASE1 2

Status

Recruiting 2Completed 2Withdrawn 1

Sponsor Class

OTHER 5

Study Type

Interventional 5

Sponsor

Cancer Type

Lymphoid 5Other hematologic neoplasm 1

Conditions

Lymphoma, B-Cell 2Motor Activity 1Lymphoma, Large B-Cell, Diffuse 1Lymphoma 1Leukemia 1Advanced B-cell Lymphoid Malignancies 1

Interventions

Cyclophosphamide 2042Radiotherapy 1859Cisplatin 1825Carboplatin 1533Gemcitabine 1434Paclitaxel 1289Bevacizumab 1270Docetaxel 1202pembrolizumab 1199Oxaliplatin 1160Capecitabine 1144Fluorouracil 1061Dexamethasone 971Rituximab 919Nivolumab 908Magnetic Resonance Spectroscopy 862Etoposide 839Doxorubicin 823Drug Therapy 792Radiosurgery 776Irinotecan 775Cytarabine 736fludarabine 716Leucovorin 676Lenalidomide 608fludarabine phosphate 564Temozolomide 552Radiation 541Filgrastim 540Cetuximab 537

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
OTHER × Interventional × Roflumilast × Clear all
NCT06643221 2026-06-05

Allo-X

University of Arizona

Phase EARLY_PHASE1 Recruiting
200 enrolled
LymphoidOther hematologic neoplasm

Leukemia, Lymphoma, Motor Activity

NCT06977711 2025-08-05

Loncastuximab and Roflumilast Added to R-CHOP (Lo-(Rituximab and Roflumilast) RR-CHOP) for Naïve High-Risk Diffuse Large B-cell Lymphoma (DLBCL)

The University of Texas Health Science Center at San Antonio

Phase 1 Recruiting
10 enrolled
Lymphoid

Lymphoma, Large B-Cell, Diffuse

NCT05796271 2024-02-29

Clinical Trial of Roflumilast Added to Standard Chemoimmunotherapy

The University of Texas Health Science Center at San Antonio

Phase 1 Withdrawn
Lymphoid

Lymphoma, B-Cell

NCT03458546 2024-02-21

Study of Roflumilast in Combination With Standard Chemotherapy for High-risk Diffuse Large B-cell Lymphoma

The University of Texas Health Science Center at San Antonio

Phase 1 Completed
14 enrolled
Lymphoid

Lymphoma, B-Cell

NCT01888952 2017-02-27

Phase 0/1 Biomarker and Pharmacodynamic Study of Roflumilast in Patients With Advanced B-Cell Hematologic Malignancies (CTRC# 13-0013)

The University of Texas Health Science Center at San Antonio

Phase EARLY_PHASE1 Completed
10 enrolled 4 charts
Lymphoid

Advanced B-cell Lymphoid Malignancies

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