Clinical Trials

TP53 Y220C Mutation

NCT07088913 2026-03-03

A Study to Investigate the Effect of Capivasertib on the Pharmacokinetics of Oral Rosuvastatin in Healthy Participants

20 enrolled

Healthy Participants

NCT07235748 2026-02-17

Drug-drug Interaction Study of Vorasidenib With Bupropion, Repaglinide, Flurbiprofen, Omeprazole, Midazolam, and Rosuvastatin in Healthy Adult Participants

28 enrolled

Healthy Adult Participants

NCT05828303 2025-04-01

A Phase 1 Study to Evaluate the Potential Drug Interactions Between Repotrectinib and Metformin, Digoxin, and Rosuvastatin in Patients With Advanced Solid Tumors

Phase 1 Withdrawn

Tumor-Agnostic

Neoplasm Metastasis

NCT04542382 2025-03-30

BCRPmarker

11 enrolled

Healthy Volunteers

NCT06677957 2025-01-03

A Clinical Trial to Investigate the Clinical Drug-Drug Interaction of Divarasib With Probe Substrates of P-Glycoprotein and Breast Cancer Resistance Protein in Healthy Participants

19 enrolled

Healthy Participants

NCT05926180 2024-12-13

Assessing the Effect of DZD9008 on the Pharmacokinetics of the Cocktail Probes Representative for CYP3A4, P-gp, BCRP and OATP1B1 in Patients with EGFR or HER2 Mutant Advanced Non-small Cell Lung Cancer (WU-KONG19)

25 enrolled

Carcinoma, Non-Small-Cell Lung

NCT04094519 2024-11-20

A Study to Evaluate the Effect of Multiple Doses of Enzalutamide on the Pharmacokinetics of Substrates of P-glycoprotein (Digoxin) and Breast Cancer Resistant Protein (Rosuvastatin) in Male Subjects With Prostate Cancer

24 enrolled

Genitourinary

Prostatic Neoplasms

NCT03864042 2024-09-27

Pharmacokinetic Drug-drug Interaction Study of Encorafenib and Binimetinib on Probe Drugs in Patients With BRAF V600-mutant Melanoma or Other Advanced Solid Tumors

56 enrolled 158 charts

Dermatologic

Melanoma

NCT06329895 2024-07-05

A Study to Learn About How BAY2927088 Affects the Level of Dabigatran or Rosuvastatin in the Blood When These Drugs Are Taken Together in Healthy Participants

15 enrolled

Advanced Non-small Cell Lung Cancer

NCT04887194 2024-05-08

PK Study to Assess Drug-drug Interaction and QTc Between Sitravatinib and a Cocktail of Substrates

40 enrolled

Advanced Solid Tumor

NCT06348290 2024-04-04

Study to Evaluate the Drug-drug Interaction of JMKX001899 in Healthy Subjects

Phase 1 Unknown

72 enrolled

Solid Tumor, Adult

NCT05395117 2023-12-13

A Study to Assess the Effect of AZD5462 on the Pharmacokinetics of Midazolam, Rosuvastatin and Digoxin

32 enrolled

Healthy Participants

NCT05045638 2023-08-14

Effect of Coadministration of Sotorasib on the Pharmacokinetics of Rosuvastatin in Healthy Participants

13 enrolled 14 charts

Healthy Participants

NCT04889287 2023-08-09

A Study to Learn How Much Rosuvastatin Gets Into the Blood When Taken With or Without Elinzanetant and to Learn About the Safety of Elinzanetant in Healthy Participants

16 enrolled

Endocrine

Multiple Endocrine Neoplasia Type 1

NCT03954366 2023-06-08

Drug-Drug Interaction Study of Rucaparib, Rosuvastatin and Oral Contraceptives

36 enrolled

Tumor-Agnostic

Neoplasms

NCT05708573 2023-04-14

Potential Drug Interaction Between ALXN2040 and Rosuvastatin

20 enrolled

Healthy Participants

NCT05368805 2022-10-06

Fruquintinib DDI Study With P-gp and BCRP Substrates

32 enrolled

Gastrointestinal

Colorectal Neoplasms

NCT04428086 2022-07-26

A Pharmacokinetic Interaction Study Between Apatinib and Rosuvastatin or Metformin in Solid Tumor Subjects.

19 enrolled

Solid Tumor, Adult

NCT04252300 2021-03-11

Study to Learn the Effect of Drug BAY1817080 on the Way the Body Absorbs, Distributes and Excretes Another Drug Rosuvastatin in Healthy Adult Participants

14 enrolled

Chronic Cough, Pain

NCT02626234 2020-12-10

A Drug-drug Interaction (DDI) Study to Assess the Effect of INC280 on the Pharmacokinetics of Digoxin and Rosuvastatin in Patients With cMET-dysregulated Advanced Solid Tumors

32 enrolled

cMET-dysregulated Advanced Solid Tumors

NCT04621669 2020-11-09

Drug-durg Interaction of SHR3680 With Digoxin, Rosuvastatin Calcium and Metformin Hydrochloride

Phase 1 Unknown

18 enrolled

Drug-drug Interaction,SHR3680

NCT00966472 2020-04-21

Phase I Study of a Statin + Erlotinib for Advanced Solid Malignancies With Focus on Squamous Cell Carcinomas and NSCLC

24 enrolled

Carcinoma, Non-Small-Cell Lung, Carcinoma, Squamous Cell

NCT02106845 2019-06-07

Effect of Regorafenib on Digoxin and Rosuvastatin in Patients With Advanced Solid Malignant Tumors.

42 enrolled

Tumor-Agnostic

Neoplasms

NCT01051401 2018-08-01

Rosuvastatin in Treating Women With Cardiovascular Complications Who Are Undergoing Chemotherapy For Breast Cancer

Phase 1 Terminated

5 enrolled

Breast

Breast Neoplasms

NCT02317016 2018-07-31

Study to Assess the Effect of AZD9291 on the Blood Levels of Rosuvastatin, in Patients With EGFRm+ Non-small Cell Lung Cancer

44 enrolled 20 charts

Carcinoma, Non-Small-Cell Lung, Neoplasms

NCT02483871 2017-06-05

Dose Optimization of Rosuvastatin in Early Stage and Metastatic Estrogen Receptor Positive Breast Cancer Patients on Endocrine Therapy

Phase 1 Withdrawn

Breast

Breast Neoplasms

NCT02671097 2016-09-08

Drug-drug Interaction Study Using Rosuvastatin as a Breast Cancer Resistant Protein (Efflux Transporter), Organic Anion-transporting Polypeptide (OATP)1B1, and OATP1B3 (Uptake Transporters) Probe Substrate

30 enrolled

Healthy Volunteers

NCT02300363 2015-07-09

DDI Study With Multiple-dose LX4211 and Single Dose Rosuvastatin