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Phase

Phase 4 2Phase 2 2Phase 2/3 1

Status

Completed 5Unknown 2

Sponsor Class

OTHER 4NIH 1

Study Type

Interventional 5

Sponsor

Cancer Type

Gastrointestinal 2Other hematologic neoplasm 1Lymphoid 1Genitourinary 1Breast 1

Conditions

Prostatic Neoplasms 1Precursor Cell Lymphoblastic Leukemia-Lymphoma 1Leukemia 1Gastrointestinal Neoplasms 1Drug-Related Side Effects and Adverse Reactions 1Colorectal Neoplasms 1Cardiotoxicity 1Breast Neoplasms 1

Interventions

Cyclophosphamide 1499Cisplatin 1435Paclitaxel 1340Radiotherapy 1310Carboplatin 1267Gemcitabine 1226Docetaxel 1133Bevacizumab 1070Fluorouracil 906Doxorubicin 805Dexamethasone 755Rituximab 744Capecitabine 735Oxaliplatin 709pembrolizumab 700Etoposide 679Irinotecan 639Filgrastim 624Cytarabine 587Nivolumab 586Leucovorin 583Vincristine 517Cetuximab 479Prednisone 478Bortezomib 474Trastuzumab 468Erlotinib Hydrochloride 467Surveys and Questionnaires 460Methotrexate 444Lenalidomide 436

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Completed × Silymarin × Clear all
NCT04434404 2020-06-16

Evaluation of the Cardioprotective Effect of L-carnitine and Silymarin in Patients Receiving Anthracycline Chemotherapy

Horus University

Phase 4 Completed
83 enrolled
Breast

Breast Neoplasms, Cardiotoxicity

NCT03130634 2020-05-13

The Efficacy of Silymarin as Adjuvant Therapy on Colorectal Cancer Patients Undergoing FOLFIRI Treatment

Kaohsiung Medical University Chung-Ho Memorial Hospital

Phase 4 Completed
70 enrolled
Gastrointestinal

Colorectal Neoplasms

NCT01829178 2015-05-13

Evaluation of Effects of Silymarin on Cisplatin Induced Nephrotoxicity in Upper Gastrointestinal Adenocarcinoma

Tehran University of Medical Sciences

Phase 2/3 Completed
30 enrolled
Gastrointestinal

Gastrointestinal Neoplasms

NCT00487721 2014-03-31

The Effect of High-dose Silybin-phytosome in Men With Prostate Cancer

University of Colorado, Denver

Phase 2 Completed
12 enrolled 10 charts
Genitourinary

Prostatic Neoplasms

NCT00055718 2013-12-18

Silymarin (Milk Thistle Extract) in Treating Patients With Acute Lymphoblastic Leukemia Who Are Receiving Chemotherapy

National Cancer Institute (NCI)

Phase 2 Completed
50 enrolled
LymphoidOther hematologic neoplasm

Leukemia, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Drug-Related Side Effects and Adverse Reactions

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