NCT05821556 2026-04-14
Valproic Acid/Simvastatin Plus Gemcitabine/Nab-paclitaxel Based Regimens in Untreated Metastatic Pancreatic Adenocarcinoma Patients
National Cancer Institute, Naples
Phase 2 Recruiting
Clinical Trials
33 trialsNCT02968810 2026-04-13
Simvastatin in Preventing Liver Cancer in Patients With Liver Cirrhosis
National Cancer Institute (NCI)
Phase 2 Active not recruiting
NCT05586360 2026-03-04
T-reg Function Changes: a Novel Immune Regulatory Effect Underlying Benefit of Statin Use on Lethal Prostate Cancer
Medical University of South Carolina
Phase 2 Recruiting
NCT03400826 2025-07-14
Effects of Simvastatin on Uterine Leiomyoma Size
Johns Hopkins University
Phase 2 Recruiting
NCT07003815 2025-06-04
Envafolimab With Chemotherapy and Simvastatin in Advanced Biliary Tract Cancer
Tongji Hospital
Phase 2 Not yet recruiting
NCT03324425 2025-02-27
SIMPHONY
Baylor Breast Care Center
Phase 2 Active not recruiting
NCT05550415 2024-10-03
The Role of Simvastatin in the Epithelial-Mesenchymal Transition Process of Breast Cancer
Indonesia University
Phase 2 Recruiting
NCT02096588 2024-07-09
Detection and Prevention of Anthracycline-Related Cardiac Toxicity With Concurrent Simvastatin
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Phase 2 Terminated
NCT03454529 2023-08-01
The Effect of Simvastatin on Breast Cancer Cell Growth in Women With Stage I-II Breast Cancer
Barbara Ann Karmanos Cancer Institute
Phase 2 Completed
NCT01156545 2022-04-06
BIBW 2992 Plus Simvastatin vs. BIBW 2992 in Previously Treated Patients With Advanced Non-adenocarcinomatous NSCLC
National Cancer Center, Korea
Phase 2 Completed
NCT01441349 2022-04-06
Irinotecan/Cisplatin With or Without Simvastatin in Chemo-naive Patients With Extensive Disease-small Cell Lung Cancer
National Cancer Center, Korea
Phase 2 Unknown
NCT04985201 2021-08-09
Combined Simvastatin and Irinotecan in Treating ES-SCLC Patients Relapsed From 1st Chemotherapy
Shanghai Pulmonary Hospital, Shanghai, China
Phase 2 Unknown
NCT04698941 2021-07-29
Combined Simvastatin and Albumin Paclitaxel in Treating ES-SCLC Patients Relapsed From 1st Chemotherapy
Shanghai Pulmonary Hospital, Shanghai, China
Phase 2 Unknown
NCT04418089 2020-06-05
Simvastatin Effect in Combination With Neoadjuvant Chemotherapy to Clinical Response and Tumor-Free Margin in Locally Advanced Breast Cancer
Indonesia University
Phase 2 Completed
NCT02161822 2020-03-25
Capecitabine Plus Simvastatin in Locally Advanced Rectal Cancer Patients
Samsung Medical Center
Phase 2 Unknown
NCT00334542 2019-04-03
Simvastatin in Preventing a New Breast Cancer in Women at High Risk for a New Breast Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Phase 2 Completed
NCT02026583 2018-01-17
A Single Arm, Phase II Study of Simvastatin Plus XELOX and Bevacizumab as First-line Chemotherapy in Metastatic Colorectal Cancer Patients
Samsung Medical Center
Phase 2 Completed
NCT01332617 2017-12-29
Phase II Study of Simvastatin for Relapsed/Refractory Myeloma
University of Louisville
Phase 2 Withdrawn
NCT00452244 2017-08-25
Gefitinib With or Without Simvastatin in Non-Small Cell Lung Cancer (NSCLC)
National Cancer Center, Korea
Phase 2 Completed
NCT00944463 2017-02-17
Trial of Simvastatin and Gemcitabine in Pancreatic Cancer Patients
Samsung Medical Center
Phase 2 Completed
NCT02360618 2016-07-11
Metformin and Simvastatin Use in Bladder Cancer
London Health Sciences Centre
Phase 2 Unknown
NCT02104193 2016-02-17
Simvastatin Effect on Radiation Therapy of Brain Metastases
Ain Shams University
Phase 2 Completed
NCT00575965 2015-12-16
Simvastatin in Waldenstrom's Macroglobulinemia
Dana-Farber Cancer Institute
Phase 2 Terminated
NCT01561482 2015-07-22
Study of Metformin With Simvastatin for Men With Prostate Carcinoma
Baylor College of Medicine
Phase 2 Withdrawn
NCT00503763 2015-04-16
PSMMSS
Meir Medical Center
Phase 2 Withdrawn
NCT01500577 2014-06-18
A Prevention Trial in Subjects at High Risk for Breast Cancer
European Institute of Oncology
Phase 2 Completed
NCT00807950 2014-01-22
Phase II Study of Simvastatin in Primary Breast Cancer; Test of Its Potential Selectivity on Basal Subtype Breast Cancer
National University Hospital, Singapore
Phase 2 Unknown
NCT01110785 2013-09-17
Simvastatin and Panitumumab in Treating Patients With Advanced or Metastatic Colorectal Cancer
National Cancer Institute (NCI)
Phase 2 Unknown
NCT01190462 2013-08-12
Cetuximab and Simvastatin in Treating Patients With Advanced or Metastatic Colorectal Cancer
National Cancer Institute (NCI)
Phase 2 Unknown
NCT00354640 2013-06-24
Simvastatin and Anastrozole in Treating Postmenopausal Women With Ductal Carcinoma In Situ or Invasive Breast Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Phase 2 Completed
NCT00452634 2013-06-19
Irinotecan/Cisplatin Plus Simvastatin in Extensive Disease-Small Cell Lung Cancer (ED-SCLC)
National Cancer Center, Korea
Phase 2 Completed
NCT00313859 2012-02-02
Phase II Study of Simvastatin Plus Irinotecan, Fluorouracil, and Leucovorin(FOLFIRI) for Metastatic CRC
Samsung Medical Center
Phase 2 Completed
NCT00399867 2006-12-20
Simvastatin as Inhibitor of Cell Adhesion Mediated Drug Resistance in Patients With Refractory Multiple Myeloma.
Ludwig-Maximilians - University of Munich
Phase 2 Completed