Clinical Trials Browser

Phase 3 × Completed × Sirolimus × Clear all

NCT01231412 2026-04-30

Graft-Versus-Host Disease Prophylaxis in Treating Patients With Hematologic Malignancies Undergoing Unrelated Donor Peripheral Blood Stem Cell Transplant

Phase 3 Completed

174 enrolled 12 charts

LymphoidMyeloidOther hematologic neoplasmPlasma cell

Hodgkin Disease, Waldenstrom Macroglobulinemia, Multiple Myeloma, Myelodysplastic Syndromes, Myeloproliferative Disorders, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Prolymphocytic, T-Cell, Leukemia, Prolymphocytic, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Lymphoma, Large B-Cell, Diffuse, Hematologic Neoplasms, Lymphoma, Mantle-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00133887 2025-12-26

TUMORAPA 1: Efficacy of Rapamycin in Secondary Prevention of Skin Cancers in Kidney Transplant Recipients

Phase 3 Completed

Carcinoma, Squamous Cell, Skin Neoplasms

NCT03112603 2025-08-12

A Study of Ruxolitinib vs Best Available Therapy (BAT) in Patients With Steroid-refractory Chronic Graft vs. Host Disease (GvHD) After Bone Marrow Transplantation (REACH3)

Phase 3 Completed

330 enrolled 32 charts 1 FDA

Bronchiolitis Obliterans Syndrome, Graft vs Host Disease

NCT00414648 2023-11-02

MILES

Phase 3 Completed

89 enrolled 15 charts

Lymphangioleiomyomatosis

NCT00406393 2023-01-04

BMT CTN 0402

Phase 3 Completed

304 enrolled 20 charts

LymphoidMyeloidOther hematologic neoplasm

Myelodysplastic Syndromes, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00382109 2019-08-07

Tacrolimus and Methotrexate With or Without Sirolimus in Preventing Graft-Versus-Host Disease in Young Patients Undergoing Donor Stem Cell Transplant for Acute Lymphoblastic Leukemia in Complete Remission

Phase 3 Completed

146 enrolled 14 charts

LymphoidOther hematologic neoplasm

Graft vs Host Disease, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00928018 2019-02-01

Tacrolimus/Sirolimus/Methotrexate vs Tacrolimus/Methotrexate or Cyclosporine/Mycophenolate Mofetil for GVHD Prophylaxis After Reduced Intensity Allogeneic Stem Cell Transplantation for Patients With Lymphoma

Phase 3 Completed

139 enrolled 11 charts

Graft vs Host Disease, Hodgkin Disease, Lymphoma, Non-Hodgkin

NCT03140449 2017-05-04

Topical Rapamycin and Calcitriol for Angiofibroma of Tuberous Sclerosis

Phase 3 Completed

Tuberous Sclerosis

NCT00355862 2014-07-30

Immunosuppression in Patients Undergoing Liver Transplantation for Hepatocellular Carcinoma

Phase 3 Completed

Gastrointestinal

Carcinoma, Hepatocellular

NCT00928798 2012-03-08

Topical Rapamycin for Fibrofolliculomas

Phase 3 Completed

Birt-Hogg-Dube Syndrome