A Study to Investigate the Effects of Multiple Doses of Rezatapopt on the Pharmacokinetics of Metformin, Rosuvastatin, Repaglinide, and Midazolam in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation.
Phase 1 Recruiting
14 enrolled
Dose Escalation and Cohort Expansion Study of Niraparib and Dostarlimab in Paediatric Participants With Solid Tumors (SCOOP)
Phase 1 Terminated
47 enrolled 43 charts
Study to Evaluate the Safety, Tolerate, Pharmacokinetics and Preliminary Efficacy of CYH33
Phase 1 Completed
206 enrolled
A Mass Balance Study of [14C]-Nanatinostat and Relative Bioavailability Study of Nanatinostat in Patients With Advanced Cancers
Phase 1 Terminated
8 enrolled
A Crossover Bioequivalence Study of Olaparib Tablets, 150 mg (Lek Pharmaceuticals d.d.) and Lynparza® (Olaparib) Tablets 150 mg (AstraZeneca Pharmaceuticals LP), in Patients With Breast Cancer Gene (BRCA) Mutated Ovarian Cancer, Recurrent Ovarian Cancer or Metastatic Breast Cancer
Phase 1 Completed
70 enrolled 13 charts
GM-CLAG in Relapsed/Refractory FLT3-mutated AML
Phase 1 Withdrawn
Dose Escalation Pan-FGFR (Fibroblast Growth Factor Receptor) Inhibitor (Rogaratinib)
Phase 1 Completed
168 enrolled 59 charts
Determination of the Relative Bioavailability of ARQ 197 Tablet Formulation With Capsule C Formulation as a Reference in Subjects With Advanced Solid Tumors
Phase 1 Completed
24 enrolled
Weekly Administration of (bi-)Daily Oral Docetaxel in Combination With Ritonavir
Phase 1 Completed
57 enrolled
A Study to Compare the Pharmacokinetics and Safety/Tolerability of BR-UPS (Ulipristal Acetate) 5 mg Tablet With Inisia (Ulipristal Acetate) 5 mg Tablet
Phase 1 Withdrawn
Ipatasertib (GDC-0068) Study to Evaluate Formulation Change and Food Effect on Bioavailability in Healthy Subjects
Phase 1 Completed
18 enrolled
Study to Determine the Safety, Maximum Tolerated Dose, Pharmacokinetics of Sorafenib (BAY43-9006)
Phase 1 Completed
158 enrolled 17 charts
Study of Granisetron Hydrochloride Nasal Spray (GNS) in Healthy Volunteers
Phase 1 Completed
50 enrolled
Rapamycin Plus Bevacizumab in Advanced Cancers
Phase 1 Completed
28 enrolled
Bioequivalence of An Oral Mercaptopurine Suspension 100 Mg / 5 Ml Versus Tablet in Healthy Male Subjects Under Fasting Conditions
Phase 1 Completed
70 enrolled