Clinical Trials

74 enrolled

Glioblastoma

NCT02311920 2023-01-10

Ipilimumab and/or Nivolumab in Combination With Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma or Gliosarcoma

32 enrolled

Sarcoma

Gliosarcoma

NCT00994071 2019-12-09

A Phase I Study of ABT-888, an Oral Inhibitor of Poly(ADP-ribose) Polymerase and Temozolomide in Children With Recurrent/Refractory CNS Tumors

9 enrolled

Astrocytoma, Brain Neoplasms, Ependymoma, Medulloblastoma, Neuroectodermal Tumors, Primitive

NCT01119599 2015-09-29

RO4929097, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Malignant Glioma

22 enrolled

Astrocytoma, Craniopharyngioma, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Meningioma, Neuroma, Acoustic, Oligodendroglioma, Pinealoma, Choroid Plexus Neoplasms, Neuroectodermal Tumors, Primitive, Glioma, Subependymal, Gliosarcoma

NCT00020150 2015-04-29

Temozolomide and O6-benzylguanine in Treating Children With Solid Tumors

CNSGastrointestinalGenitourinaryGynecologicSarcoma

Familial ependymoma, Ovarian Germ Cell Cancer, Astrocytoma, Kidney Neoplasms, Liver Neoplasms, Medulloblastoma, Wilms Tumor, Neuroblastoma, Oligodendroglioma, Ovarian Neoplasms, Sarcoma, Osteosarcoma, Teratoma, Testicular Neoplasms, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral, Optic Nerve Glioma

NCT00049387 2015-04-15

Tipifarnib, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme or Gliosarcoma

19 enrolled

Glioblastoma, Gliosarcoma

NCT02227901 2014-12-23

Tipifarnib, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

19 enrolled

Glioblastoma, Gliosarcoma

NCT00946335 2014-07-09

ABT-888 and Temozolomide in Treating Young Patients With Recurrent or Refractory CNS Tumors

31 enrolled

Familial ependymoma, Astrocytoma, Medulloblastoma, Oligodendroglioma, Spinal Cord Neoplasms, Choroid Plexus Neoplasms, Rhabdoid Tumor, Optic Nerve Glioma

NCT00650923 2014-05-30

Aflibercept, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed or Recurrent Glioblastoma Multiforme, Gliosarcoma, or Other Malignant Glioma

61 enrolled

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Gliosarcoma

NCT01141244 2014-04-10

Temsirolimus, Irinotecan Hydrochloride, and Temozolomide in Treating Younger Patients With Relapsed or Refractory Solid Tumors

72 enrolled

Other solid neoplasm

Unspecified Childhood Solid Tumor, Protocol Specific

NCT00052780 2013-09-30

Temozolomide and O6-Benzylguanine in Treating Children With Recurrent Brain Tumors

72 enrolled

Familial ependymoma, Astrocytoma, Medulloblastoma, Oligodendroglioma, Choroid Plexus Neoplasms, Optic Nerve Glioma

NCT00003747 2013-09-20

Carboplatin and Temozolomide in Treating Patients With Unresectable or Metastatic Melanoma

Phase 1 Unknown

30 enrolled

Dermatologic

Melanoma

NCT00016055 2013-09-20

Biological Therapy and Temozolomide in Treating Patients With Metastatic Melanoma

Phase 1 Unknown

18 enrolled

Dermatologic

Melanoma

NCT00098436 2013-07-18

Temozolomide and VNP40101M in Treating Patients With Relapsed or Refractory Leukemias

LymphoidOther hematologic neoplasm

25 enrolled

Congenital Abnormalities, Blast Crisis, Leukemia, Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00077454 2013-06-05

Erlotinib and Temozolomide in Treating Young Patients With Recurrent or Refractory Solid Tumors

95 enrolled

Familial ependymoma, Astrocytoma, Medulloblastoma, Neuroblastoma, Osteosarcoma

NCT01076530 2013-05-03

Vorinostat and Temozolomide in Treating Young Patients With Relapsed or Refractory Primary Brain Tumors or Spinal Cord Tumors

27 enrolled

CNSEndocrine

Familial ependymoma, Astrocytoma, Medulloblastoma, Oligodendroglioma, Paraganglioma, Extra-Adrenal, Spinal Cord Neoplasms, Choroid Plexus Neoplasms, Rhabdoid Tumor, Optic Nerve Glioma

NCT00316849 2013-04-10

Temsirolimus, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

56 enrolled

Glioblastoma, Gliosarcoma

NCT00005637 2013-04-04

Combination Chemotherapy Following Radiation Therapy in Treating Patients With Malignant Glioma

Astrocytoma, Ependymoma, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

NCT00303940 2012-03-15

Talabostat Combined With Temozolomide or Carboplatin in Treating Young Patients With Relapsed or Refractory Brain Tumors or Other Solid Tumors