Announcements Trials
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Phase

Phase 2 44Phase 1/2 31Phase 1 20Phase 3 13Phase EARLY_PHASE1 5Phase NA 2Phase 2/3 2

Status

Completed 7Recruiting 5Active not recruiting 3Withdrawn 2Terminated 1

Sponsor Class

OTHER 5

Study Type

Interventional 5

Sponsor

Cancer Type

CNS 5

Conditions

Glioma 2Glioblastoma 2Rhabdoid Tumor 1Pyloric Stenosis, Hypertrophic 1Pinealoma 1Neuroectodermal Tumors, Primitive 1Neuroblastoma 1Medulloblastoma 1Brain Neoplasms 1

Interventions

Magnetic Resonance Spectroscopy 17Cyclophosphamide 16fludarabine 12Specimen Handling 12Fluorodeoxyglucose F18 7pembrolizumab 6X-Rays 6Nivolumab 6Temozolomide 5Radiotherapy 5Immunotherapy, Adoptive 5lenvatinib 4Paclitaxel 4Leukapheresis 4Immune Checkpoint Inhibitors 4Etoposide 4Cisplatin 4Carboplatin 4ruxolitinib 3fluciclovine F-18 3Tirzepatide 3Surgical Procedures, Operative 3Doxorubicin 3Dasatinib 3Cholecalciferol 3Biopsy 368Ga-FAPI 32-phenyl-6-(2'-(4'-(ethoxycarbonyl)thiazolyl))thiazolo(3,2-b)(1,2,4)triazole 3tislelizumab 2palbociclib 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Phase EARLY_PHASE1 × Recruiting × Temozolomide × Clear all
NCT03122197 2026-04-16

Study of Letrozole in Recurrent Gliomas

University of Cincinnati

Phase EARLY_PHASE1 Recruiting
39 enrolled
CNS

Brain Neoplasms

NCT06942039 2026-02-27

Pilot Study of IT Topotecan and Maintenance Chemotherapy for HR-EBTs in Children < 6 Years, Post Consolidation

C17 Council

Phase EARLY_PHASE1 Recruiting
15 enrolled
CNS

Medulloblastoma, Neuroblastoma, Pinealoma, Neuroectodermal Tumors, Primitive, Rhabdoid Tumor, Pyloric Stenosis, Hypertrophic

NCT07025226 2026-01-26

Senolytics

Mayo Clinic

Phase EARLY_PHASE1 Recruiting
10 enrolled
CNS

Glioma

NCT06072586 2025-11-20

A Phase 0/1 Study of BDTX-1535 in Recurrent High-Grade Glioma (rHGG) and Newly Diagnosed Glioblastoma (nGBM) Participants With EGFR Alterations or Fusions

St. Joseph's Hospital and Medical Center, Phoenix

Phase EARLY_PHASE1 Recruiting
82 enrolled
CNS

Glioblastoma, Glioma

NCT06831526 2025-11-12

Neoadjuvant Chemoradiotherapy With or Without Concurrent Azeliragon in Patients With Newly Diagnosed Glioblastoma

Washington University School of Medicine

Phase EARLY_PHASE1 Recruiting
12 enrolled
CNS

Glioblastoma

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