Announcements Trials
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Phase

Phase 1 5Phase EARLY_PHASE1 2Phase 2 2

Status

Completed 5Withdrawn 1

Sponsor Class

OTHER 4NIH 1

Study Type

Interventional 5

Sponsor

Cancer Type

Tumor-Agnostic 2Other hematologic neoplasm 1Head & Neck 1CNS 1

Conditions

Neoplasms 2Squamous Cell Carcinoma of Head and Neck 1Leukemia, Myeloid, Acute 1Head and Neck Neoplasms 1Central Nervous System Neoplasms 1Brain Neoplasms 1

Interventions

Paclitaxel 291Gemcitabine 254Carboplatin 253Cisplatin 250Radiotherapy 219Cyclophosphamide 218Irinotecan 184pembrolizumab 180Docetaxel 174Bevacizumab 166Capecitabine 148Nivolumab 141Fluorouracil 132Dexamethasone 125Bortezomib 123Oxaliplatin 115Cytarabine 113Erlotinib Hydrochloride 112Temozolomide 110Sorafenib 110Doxorubicin 106Rituximab 105Leucovorin 105Etoposide 105Filgrastim 99Everolimus 97Lenalidomide 95Ipilimumab 90Pemetrexed 89fludarabine phosphate 84

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Phase 1 × Completed × Tetrahydrouridine × Clear all
NCT01534598 2026-02-10

FdCyd and THU for Advanced Solid Tumors

National Institutes of Health Clinical Center (CC)

Phase 1 Completed
59 enrolled
Tumor-Agnostic

Neoplasms

NCT00077051 2016-12-15

Cytochlor and Tetrahydrouridine as Radiosensitizers and Cisplatin Combined With Radiation Therapy in Treating Patients With Advanced Squamous Cell Carcinoma of the Oral Cavity (Mouth) or Oropharynx (Throat)

University of Miami

Phase 1 Completed
1 enrolled
Head & Neck

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT01041443 2015-06-08

5-Fluoro-2'-Deoxycytidine and Tetrahydrouridine in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndromes

City of Hope Medical Center

Phase 1 Completed
25 enrolled
Other hematologic neoplasm

Leukemia, Myeloid, Acute

NCT00359606 2015-05-06

5-Fluoro-2'-Deoxcyctidine and Tetrahydrouridine to Treat Patients With Advanced Cancer

City of Hope Medical Center

Phase 1 Completed
58 enrolled
Tumor-Agnostic

Neoplasms

NCT00521183 2014-11-25

Cytochlor, Tetrahydrouridine, and External-Beam Radiation Therapy in Treating Patients With Cancer That Has Spread to the Brain

University of Miami

Phase 1 Completed
2 enrolled
CNS

Brain Neoplasms, Central Nervous System Neoplasms

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