Clinical Trials Browser

Completed × Tiragolumab × Clear all

Carcinoma, Non-Small-Cell Lung

NCT04619797 2026-06-03

SKYSCRAPER-06

Phase 2/3 Completed

542 enrolled 28 charts

Thoracic

Carcinoma, Non-Small-Cell Lung

NCT04665843 2026-05-05

SKYSCRAPER-09

Phase 2 Completed

123 enrolled 22 charts

Head & Neck

Squamous Cell Carcinoma of Head and Neck

NCT03563716 2026-05-04

A Study of Tiragolumab in Combination With Atezolizumab in Chemotherapy-Naïve Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer

Phase 2 Completed

135 enrolled 19 charts

Thoracic

Carcinoma, Non-Small-Cell Lung

NCT04540211 2026-04-09

SKYSCRAPER-08

Phase 3 Completed

461 enrolled 24 charts

Gastrointestinal

Esophageal Neoplasms

NCT04256421 2026-04-03

SKYSCRAPER-02

Phase 3 Completed

490 enrolled 33 charts

Thoracic

Small Cell Lung Carcinoma

NCT04300647 2026-03-12

SKYSCRAPER-04

Phase 2 Completed

172 enrolled 27 charts

Gynecologic

Uterine Cervical Neoplasms

NCT05661578 2026-02-09

SKYSCRAPER-11

Phase 2 Completed

64 enrolled

Other solid neoplasm

PD-L1-selected Solid Tumors

NCT06267001 2026-02-03

SKYSCRAPER-15

Phase 3 Completed

56 enrolled

Thoracic

Carcinoma, Non-Small-Cell Lung

NCT04294810 2026-01-30

SKYSCRAPER-01

Phase 3 Completed

620 enrolled

Thoracic

Carcinoma, Non-Small-Cell Lung

NCT03869190 2026-01-22

Study Evaluating the Efficacy and Safety of Multiple Immunotherapy-Based Treatments and Combinations in Patients With Urothelial Carcinoma (MORPHEUS-UC)

Phase 1/2 Completed

272 enrolled

Genitourinary

Urinary Bladder Neoplasms, Carcinoma, Transitional Cell

NCT03281369 2025-12-15

A Study of Multiple Immunotherapy-Based Treatment Combinations in Patients With Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction Cancer (G/GEJ) or Esophageal Cancer (Morpheus-Gastric and Esophageal Cancer)

Phase 1/2 Completed

214 enrolled

Gastrointestinal

Esophageal Neoplasms

NCT05908786 2025-12-11

A Study Evaluating The Efficacy and Safety of Neoadjuvant Immunotherapy Combinations in Patients With Surgically Resectable Hepatocellular Carcinoma

Phase 1/2 Completed

62 enrolled

Gastrointestinal

Carcinoma, Hepatocellular

NCT03193190 2025-11-21

A Study of Multiple Immunotherapy-Based Treatment Combinations in Participants With Metastatic Pancreatic Ductal Adenocarcinoma (Morpheus-Pancreatic Cancer)

Phase 1/2 Completed

341 enrolled 28 charts

Gastrointestinal

Pancreatic Adenocarcinoma

NCT05459129 2025-09-15

A Study Evaluating Efficacy and Safety of Multiple Treatment Combinations in Patients With Locally Advanced Squamous Cell Carcinoma of the Head and Neck (Morpheus-Head and Neck Cancer)

Phase 1/2 Completed

12 enrolled 18 charts

Head & Neck

Squamous Cell Carcinoma of Head and Neck

NCT03977467 2025-08-27

Atezolizumab and Tiragolumab in Patients With NSCLC or Advanced Solid Tumors Having Had Prior Treatment With a PD-1 Inhibitor

Phase 2 Completed

46 enrolled 12 charts

Thoracic

Carcinoma, Non-Small-Cell Lung

NCT05116202 2025-07-18

A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Melanoma (Morpheus-Melanoma)

Phase 1/2 Completed

110 enrolled 27 charts

Dermatologic

Melanoma

NCT04632992 2025-01-08

MyTACTIC

Phase 2 Completed

252 enrolled 27 charts

Advanced Unresectable or Metastatic Solid Malignancy

NCT02794571 2024-12-05

Safety and Pharmacokinetics (PK) of Escalating Doses of Tiragolumab as a Single Agent and in Combination With Atezolizumab and/or Other Anti-Cancer Therapies in Locally Advanced or Metastatic Tumors

Phase 1 Completed

518 enrolled

Tumor-Agnostic

Neoplasm Metastasis

NCT04584112 2023-03-15

A Study of the Safety, Efficacy, and Pharmacokinetics of Tiragolumab in Combination With Atezolizumab and Chemotherapy in Participants With Triple-Negative Breast Cancer

Phase 1 Completed

83 enrolled

Breast

Triple Negative Breast Neoplasms

Clinical Trials

SKYSCRAPER-03

SKYSCRAPER-06

SKYSCRAPER-09

A Study of Tiragolumab in Combination With Atezolizumab in Chemotherapy-Naïve Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer

SKYSCRAPER-08

SKYSCRAPER-02

SKYSCRAPER-04

SKYSCRAPER-11

SKYSCRAPER-15

SKYSCRAPER-01

Study Evaluating the Efficacy and Safety of Multiple Immunotherapy-Based Treatments and Combinations in Patients With Urothelial Carcinoma (MORPHEUS-UC)

A Study of Multiple Immunotherapy-Based Treatment Combinations in Patients With Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction Cancer (G/GEJ) or Esophageal Cancer (Morpheus-Gastric and Esophageal Cancer)

A Study Evaluating The Efficacy and Safety of Neoadjuvant Immunotherapy Combinations in Patients With Surgically Resectable Hepatocellular Carcinoma

A Study of Multiple Immunotherapy-Based Treatment Combinations in Participants With Metastatic Pancreatic Ductal Adenocarcinoma (Morpheus-Pancreatic Cancer)

A Study Evaluating Efficacy and Safety of Multiple Treatment Combinations in Patients With Locally Advanced Squamous Cell Carcinoma of the Head and Neck (Morpheus-Head and Neck Cancer)

Atezolizumab and Tiragolumab in Patients With NSCLC or Advanced Solid Tumors Having Had Prior Treatment With a PD-1 Inhibitor

A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Melanoma (Morpheus-Melanoma)

MyTACTIC

Safety and Pharmacokinetics (PK) of Escalating Doses of Tiragolumab as a Single Agent and in Combination With Atezolizumab and/or Other Anti-Cancer Therapies in Locally Advanced or Metastatic Tumors

A Study of the Safety, Efficacy, and Pharmacokinetics of Tiragolumab in Combination With Atezolizumab and Chemotherapy in Participants With Triple-Negative Breast Cancer