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Phase

Phase 2 6Phase 3 5Phase 1 5Phase 1/2 2Phase 2/3 1

Status

Completed 5

Sponsor Class

NIH 3OTHER 1NETWORK 1

Study Type

Interventional 5

Sponsor

Cancer Type

Thoracic 2Other solid neoplasm 2Gynecologic 1

Conditions

Lung Neoplasms 2Uterine Cervical Neoplasms 1Unspecified Childhood Solid Tumor, Protocol Specific 1Unspecified Adult Solid Tumor, Protocol Specific 1Carcinoma, Non-Small-Cell Lung 1Adenocarcinoma of Lung 1

Interventions

Cyclophosphamide 626pembrolizumab 505Paclitaxel 456Gemcitabine 439Carboplatin 437Cisplatin 420Radiotherapy 382fludarabine 367Nivolumab 340Docetaxel 278Bevacizumab 276Irinotecan 258Magnetic Resonance Spectroscopy 245Fluorouracil 229Dexamethasone 225Specimen Handling 222Capecitabine 218Rituximab 206Oxaliplatin 201Cytarabine 201Ipilimumab 198Temozolomide 197Biopsy 197fludarabine phosphate 194Etoposide 181Lenalidomide 176Doxorubicin 175Leucovorin 174Cetuximab 171Injections 170

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Phase 1 × Interventional × Tirapazamine × Clear all
NCT00005078 2015-06-08

Tirapazamine, Carboplatin, and Paclitaxel in Treating Patients With Advanced Malignant Solid Tumors

City of Hope Medical Center

Phase 1 Completed
44 enrolled
Other solid neoplasm

Unspecified Adult Solid Tumor, Protocol Specific

NCT00098995 2013-06-26

Tirapazamine, Cisplatin, and Radiation Therapy in Treating Patients With Stage IB, Stage II, Stage III, or Stage IVA Cervical Cancer

National Cancer Institute (NCI)

Phase 1 Completed
22 enrolled
Gynecologic

Uterine Cervical Neoplasms

NCT00003288 2013-02-05

Tirapazamine Plus Cyclophosphamide in Treating Children With Refractory Solid Tumors

National Cancer Institute (NCI)

Phase 1 Completed
12 enrolled
Other solid neoplasm

Unspecified Childhood Solid Tumor, Protocol Specific

NCT00006487 2012-10-04

S0004: Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Limited-stage Small Cell Lung Cancer

SWOG Cancer Research Network

Phase 1 Completed
30 enrolled
Thoracic

Lung Neoplasms

NCT00033410 2009-02-09

Chemotherapy, Tirapazamine, and Radiation Therapy in Treating Patients With Non-Small Cell Lung Cancer

National Cancer Institute (NCI)

Phase 1 Completed
30 enrolled
Thoracic

Adenocarcinoma of Lung, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

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